Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ivy H.N. Wong"'
Publikováno v:
Annals of the New York Academy of Sciences. 945:36-50
Circulating tumor DNA in plasma and serum has been demonstrated to reflect the biological characteristics of tumors, including the rates of apoptosis and necrosis. Aberrant promoter methylation has increasingly emerged as a fundamental molecular abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d29d56067111fb7e8990b1cdf5e16cb
https://doi.org/10.1111/j.1749-6632.2001.tb03862.x
https://doi.org/10.1111/j.1749-6632.2001.tb03862.x
Autor:
Ivy H.N. Wong, Y.M. Dennis Lo
Publikováno v:
Current Oncology Reports. 4:471-477
Circulating tumor nucleic acids in blood have been demonstrated to reflect the biologic characteristics of tumors. During tumor progression, aberrant DNA methylation can lead to transcriptional silencing of tumor suppressor genes, DNA repair genes, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffc4e7d04cd580746860cb135b52912
https://doi.org/10.1007/s11912-002-0058-3
https://doi.org/10.1007/s11912-002-0058-3
Publikováno v:
Cancer Letters. 167:183-191
We assessed whether current therapies could lead to hematogenous dissemination of malignant hepatocytes in hepatocellular carcinoma (HCC) patients using semi-quantitative reverse transcription–polymerase chain reaction (RT-PCR) for alpha-fetoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e63e1ab66a3a078b5d2c4b7bfa0146c
https://doi.org/10.1016/s0304-3835(01)00455-4
https://doi.org/10.1016/s0304-3835(01)00455-4
Publikováno v:
ResearcherID
We prospectively analyzed the circulating tumor burden in colorectal cancer patients using semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) for carcinoembryonic antigen (CEA) and cytokeratin 19 (CK19 ). We distinguished the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b588a27c5fd1a723ee01c92e20827658
https://doi.org/10.1016/s0304-3835(00)00630-3
https://doi.org/10.1016/s0304-3835(00)00630-3
Publikováno v:
Blood. 95:1942-1949
We prospectively analyzed p15 and p16 promoter methylation patterns using methylation-specific polymerase chain reaction (PCR) in patients with adult and childhood acute leukemias and studied the association of methylation patterns with chromosomal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc6d300b4e9675901fdc5c16d96236cd
https://doi.org/10.1182/blood.v95.6.1942
https://doi.org/10.1182/blood.v95.6.1942
Autor:
Amanda Kan, Kenny I.K. Lei, Yuk-Fei Chung, Joseph Chuen-Kwan Lee, Margaret H.L. Ng, Kwok Wai Lo, Ivy H.N. Wong, Nicolas William Rupert Wickham
Publikováno v:
The American Journal of Pathology. 154:15-22
To gain insight into the real incidence of the numeric chromosomal aberrations and the cell lineage involvement of the neoplastic process in multiple myeloma (MM), we examined 18 Chinese MM patients by May-Grunwald-Giemsa (MGG) staining and fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cd5d127f22fb7bd35724fa2f94394d
https://doi.org/10.1016/s0002-9440(10)65245-5
https://doi.org/10.1016/s0002-9440(10)65245-5
Publikováno v:
Leukemia & Lymphoma. 34:463-472
In contrast to classical mutations, DNA methylation is a mechanism of changing the base sequence without altering the coding function of a gene. The interplay between this epigenetic modification and classical mutations plays an important role in tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c38b63a602e0766383ddb3e7d6c02a5
https://doi.org/10.3109/10428199909058473
https://doi.org/10.3109/10428199909058473
Autor:
Ivy H.N. Wong
Publikováno v:
Clinical Chemistry. 49:1429-1431
The biological cascade of cancer progression starts from uncontrolled proliferation of cells to generate a tumor mass. The enlarging tumor acquires vasculature through which malignant cells detach from the primary site and disseminate into blood, inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a99f8e476770543b9a4c98e5d7a2b44
https://doi.org/10.1373/49.9.1429
https://doi.org/10.1373/49.9.1429
Publikováno v:
Clinical Chemistry. 46:1420-1422
Detection of tumor-derived genetic and epigenetic alterations in plasma and serum may have a profound impact on the noninvasive diagnosis of cancers among high-risk populations (1)(2)(3). Chronic hepatitis infection and cirrhosis are well-documented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecf653f79612607b540ca10a2c32aab3
https://doi.org/10.1093/clinchem/46.9.1420
https://doi.org/10.1093/clinchem/46.9.1420
