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Akademický článek

Choice of step and near step profiles from splice loss analysis of trapezoidal index single mode fibers leading to a proposal of a longitudinal displacement sensor

Autor: Anirban Roy Chowdhury, Ivy Dutta, Jayee Sinha, Somenath Sarkar

Publikováno v: Results in Optics, Vol 12, Iss , Pp 100450- (2023)

In this paper, an in-depth investigation is carried out on the effect of aspect ratio on splice loss between a pair of identical single mode trapezoidal index fibers in the presence of longitudinal and transverse misalignments. Splice loss is, intere

Externí odkaz: https://doaj.org/article/f5c93aa552e444bba2e3c6d01999f73c

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CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function

Publikováno v: Science translational medicine 14 (2022). doi:10.1126/scitranslmed.abg8027
info:cnr-pdr/source/autori:Ruggiero, Eliana; Carnevale, Erica; Prodeus, Aaron; Magnani, Zulma Irene; Camisa, Barbara; Merelli, Ivan; Politano, Claudia; Stasi, Lorena; Potenza, Alessia; Cianciotti, Beatrice Claudia; Manfredi, Francesco; Di Bono, Mattia; Vago, Luca; Tassara, Michela; Mastaglio, Sara; Ponzoni, Maurilio; Sanvito, Francesca; Liu, Dai; Balwani, Ishina; Galli, Rossella; Genua, Marco; Ostuni, Renato; Doglio, Matteo; O'Connell, Daniel; Dutta, Ivy; Yazinski, Stephanie Ann; McKee, Mark; Arredouani, Mohamed Simo; Schultes, Birgit; Ciceri, Fabio; Bonini, Chiara/titolo:CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function/doi:10.1126%2Fscitranslmed.abg8027/rivista:Science translational medicine/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume:14

T cell receptor (TCR)–based therapy has the potential to induce durable clinical responses in patients with cancer by targeting intracellular tumor antigens with high sensitivity and by promoting T cell survival. However, the need for TCRs specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721e152e0f9ed32a72141cc049879e3a
https://pubmed.ncbi.nlm.nih.gov/35138911

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Prediction of unknown aspect ratio of a single mode trapezoidal index fiber using splice loss technique considering angular misalignment

Autor: Ivy Dutta, Somenath Sarkar, Dharmadas Kumbhakar

Publikováno v: Optik. 170:132-139

We use the splice loss measurement technique in absence and presence of angular misalignment and report a simple and accurate method to predict the unknown aspect ratio of a supplied circular core trapezoidal index single mode fiber. We, first, propo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2dab08257872f6d30cff8181e5b0dfda
https://doi.org/10.1016/j.ijleo.2018.05.056

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Prediction of power transmission coefficient and the aspect ratio of a single mode trapezoidal index fiber by using splice loss technique

Autor: Ivy Dutta, Anirban Roy Chowdhury, Somenath Sarkar, Aswini Kumar Mallick

Publikováno v: Optik - International Journal for Light and Electron Optics. 153:1-8

Based on the splice loss analysis between two perfectly aligned single mode step and trapezoidal index fibers, we propose a simple empirical relation of power transmission coefficient in terms of normalised frequency and aspect ratio, using a recentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec8e024fd05c52e2e5f7ea61207b040b
https://doi.org/10.1016/j.ijleo.2017.09.027

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A Novel Strategy for Off-the-Shelf T Cell Therapy Which Evades Allogeneic T Cell and NK Cell Rejection

Autor: Utsav Jetley, Daniel O′Connell, Reynald Lescarbeau, Surbhi Goel, Birgit Schultes, Marie Keenan, Palak Sharma, Simo M Arredouani, Priya Venkatesan, John Averill, Yiyang Tan, Ishina Balwani, Matthew Roy, Utkarsha Ranade, Ivy Dutta, Yong Zhang, Dai Liu, Aaron Prodeus

Publikováno v: Blood. 138:1711-1711

Introduction. Despite the success of autologous chimeric antigen receptor (CAR)-T cells, barriers to a more widespread use of this potentially curative therapy include manufacturing failures and the high cost of individualized production. There is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5621d94c5b5008ec12b414b2ef8b9d8
https://doi.org/10.1182/blood-2021-152999

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Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG

Autor: Bhushan S. Pattni, Vladimir P. Torchilin, Alexei Degterev, James D. Baleja, Aditi Jhaveri, Ivy Dutta

Publikováno v: International Journal of Pharmaceutics. 532:149-156

Cancer cells increase their metabolism to produce the energy and biomolecules necessary for growth and proliferation. Thus, energy metabolism pathways may serve as targets for anti-cancer therapy. NCL-240 is a second generation anti-cancer drug belon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fce46fab837b3cc6b95ca3f9f74399
https://doi.org/10.1016/j.ijpharm.2017.08.095

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NTLA5001, a T Cell Product Candidate with CRISPR-Based Targeted Insertion of a High-Avidity, Natural, WT1-Specific TCR, Shows Efficacy in In Vivo Models of AML and ALL

Autor: Aaron Prodeus, Amy M. Becker, Laura Sepp-Lorenzino, Maxwell Foisey, Birgit Schultes, Mark D. McKee, Simo M Arredouani, Eliana Ruggiero, Chiara Bonini, Ishina Balwani, Fabio Ciceri, Ivy Dutta, Qingzhan Zhang, Dai Liu

Publikováno v: Blood. 136:32-33

Adoptive cell therapy using T cells expressing transgenic (tg) tumor antigen-targeting T cell receptors (TCRs) has become an attractive modality to treat hematological and solid cancers due to a broader array of accessible targets relative to CAR-T c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ac5926d3af5e83428284188fe3ade30
https://doi.org/10.1182/blood-2020-143119

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NOR and NAND gates using two photon absorption in silicon wire waveguide

Autor: Anirban Roy Chowdhury, Dharmadas Kumbhakar, Ivy Dutta

Publikováno v: Optical and Quantum Electronics. 45:1319-1327

Ultrafast all-optical NOR gate based on two photon absorption (2PA) process in SOI waveguide is already established. We have designed NAND gate also based on this process with a novel waveguide coupler structure. Power attenuation due to 2PA process

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bb682153b84c70e97a66dd9d75a37bc
https://doi.org/10.1007/s11082-013-9755-4

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An Exact Analysis of the Fundamental and First Higher Order Mode in Graded Index Fibers with Direct Power Series Method

Autor: Anirban Roy Chowdhury, Dharmadas Kumbhakar, Ivy Dutta

Publikováno v: Optics and Photonics Journal. :169-177

An exact and fast analytic method based on power series is established to predict the modal field distributions, Petermann-2 spot size, the normalized propagation constant corresponding to fundamental and first higher order mode in graded index fiber

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acc1d9d67e28c2330c767c77d7acfd30
https://doi.org/10.4236/opj.2013.32028

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