Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ivory J. Mintah"'
Autor:
Rene C. Adam, Ivory J. Mintah, Corey A. Alexa-Braun, Lisa M. Shihanian, Joseph S. Lee, Poulabi Banerjee, Sara C. Hamon, Hye In Kim, Jonathan C. Cohen, Helen H. Hobbs, Cristopher Van Hout, Jesper Gromada, Andrew J. Murphy, George D. Yancopoulos, Mark W. Sleeman, Viktoria Gusarova
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 9, Pp 1271-1286 (2020)
Angiopoietin-like protein (ANGPTL)3 regulates plasma lipids by inhibiting LPL and endothelial lipase (EL). ANGPTL3 inactivation lowers LDL-C independently of the classical LDLR-mediated pathway and represents a promising therapeutic approach for indi
Externí odkaz:
https://doaj.org/article/b763cbeadcc34b4ca47920889e1ab457
Autor:
Jorge F. Haller, Ivory J. Mintah, Lisa M. Shihanian, Panayiotis Stevis, David Buckler, Corey A. Alexa-Braun, Sandra Kleiner, Serena Banfi, Jonathan C. Cohen, Helen H. Hobbs, George D. Yancopoulos, Andrew J. Murphy, Viktoria Gusarova, Jesper Gromada
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1166-1173 (2017)
Angiopoietin-like (ANGPTL)3 and ANGPTL8 are secreted proteins and inhibitors of LPL-mediated plasma triglyceride (TG) clearance. It is unclear how these two ANGPTL proteins interact to regulate LPL activity. ANGPTL3 inhibits LPL activity and increase
Externí odkaz:
https://doaj.org/article/8517d94a54094b40856d902cae268ec6
Autor:
Viktoria Gusarova, Corey A. Alexa, Yan Wang, Ashique Rafique, Jee Hae Kim, David Buckler, Ivory J. Mintah, Lisa M. Shihanian, Jonathan C. Cohen, Helen H. Hobbs, Yurong Xin, David M. Valenzuela, Andrew J. Murphy, George D. Yancopoulos, Jesper Gromada
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 7, Pp 1308-1317 (2015)
Angiopoietin-like protein 3 (ANGPTL3) is a circulating protein synthesized exclusively in the liver that inhibits LPL and endothelial lipase (EL), enzymes that hydrolyze TGs and phospholipids in plasma lipoproteins. Here we describe the development a
Externí odkaz:
https://doaj.org/article/275672f16b71425392895eda92f8dd5f
Autor:
Mark W. Sleeman, Lisa M. Shihanian, George D. Yancopoulos, Joseph Lee, Andrew J. Murphy, Jonathan Cohen, Jesper Gromada, Helen H. Hobbs, Corey A. Alexa-Braun, Viktoria Gusarova, Cristopher V. Van Hout, Sara Hamon, Poulabi Banerjee, Hye In Kim, Ivory J. Mintah, Rene C. Adam
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 9, Pp 1271-1286 (2020)
Journal of Lipid Research
Journal of Lipid Research
Angiopoietin-like protein (ANGPTL)3 regulates plasma lipids by inhibiting LPL and endothelial lipase (EL). ANGPTL3 inactivation lowers LDL-C independently of the classical LDLR-mediated pathway and represents a promising therapeutic approach for indi
Autor:
Jee Hae Kim, Lisa M. Shihanian, Buckler David R, Jonathan C. Cohen, Andrew J. Murphy, Viktoria Gusarova, Yan Wang, Ashique Rafique, Yurong Xin, David M. Valenzuela, Corey A. Alexa, George D. Yancopoulos, Helen H. Hobbs, Ivory J. Mintah, Jesper Gromada
Publikováno v:
Journal of Lipid Research. 56:1308-1317
Angiopoietin-like protein 3 (ANGPTL3) is a circulating protein synthesized exclusively in the liver that inhibits LPL and endothelial lipase (EL), enzymes that hydrolyze TGs and phospholipids in plasma lipoproteins. Here we describe the development a
Autor:
Helen H. Hobbs, Corey A. Alexa-Braun, Lisa M. Shihanian, Jesper Gromada, Buckler David R, Jonathan C. Cohen, Sandra Kleiner, Viktoria Gusarova, George D. Yancopoulos, Panayiotis Stevis, Andrew J. Murphy, Ivory J. Mintah, Serena Banfi, Jorge F. Haller
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1166-1173 (2017)
Angiopoietin-like (ANGPTL)3 and ANGPTL8 are secreted proteins and inhibitors of LPL-mediated plasma triglyceride (TG) clearance. It is unclear how these two ANGPTL proteins interact to regulate LPL activity. ANGPTL3 inhibits LPL activity and increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816f1c0ad053d6b3b385c016068627bd
https://europepmc.org/articles/PMC5454515/
https://europepmc.org/articles/PMC5454515/
Autor:
Viktoria Gusarova, Brian Zambrowicz, Andrew J. Murphy, Qi Su, Serena Banfi, Lisa M. Shihanian, Ivory J. Mintah, Helen H. Hobbs, Corey A. Alexa-Braun, Jesper Gromada, Vishal Kamat, Yurong Xin, Joseph Lee, George D. Yancopoulos, Jonathan C. Cohen
Publikováno v:
Endocrinology. 158(5)
Angiopoietin-like protein (ANGPTL)8 is a negative regulator of lipoprotein lipase-mediated plasma triglyceride (TG) clearance. In this study, we describe a fully human monoclonal antibody (REGN3776) that binds monkey and human ANGPTL8 with high affin