Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ivonne Renner"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114288 (2014)
Here we show that designed transcription activator-like effectors (TALEs) that bind to defined areas of the interferon beta promoter are capable to induce IFN-beta expression and signaling in human cells. Importantly, TALE-mediated IFN-beta signaling
Externí odkaz:
https://doaj.org/article/a619913d851442849c733ed5ab90a026
Autor:
Rene Geissler, Nancy Funk, Jan van Lunzen, Jan Chemnitz, Martina Behrens, Sven-Erik Behrens, Ilona Hauber, Heidi Baum, Ivonne Renner, Helga Hofmann-Sieber, Annekatrin Richter, Jens Boch, Joachim Hauber
Publikováno v:
Virology. 486
The major obstacle to cure infections with human immunodeficiency virus (HIV-1) is integrated proviral genomes, which are not eliminated by antiretroviral therapies (ART). Treatment approaches with latency-reversing agents (LRAs) aim at inducing prov
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114288 (2014)
PLoS ONE
PLoS ONE
Here we show that designed transcription activator-like effectors (TALEs) that bind to defined areas of the interferon beta promoter are capable to induce IFN-beta expression and signaling in human cells. Importantly, TALE-mediated IFN-beta signaling