Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ivonne Nel"'
Autor:
Benjamin Wolf, Laura Weydandt, Nadja Dornhöfer, Grit Gesine Ruth Hiller, Anne Kathrin Höhn, Ivonne Nel, Rakesh K. Jain, Lars-Christian Horn, Bahriye Aktas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract In cancer of the uterine cervix, the role of desmoplasia, i.e., peritumoral stromal remodeling characterized by fibroblast activation and increased extracellular matrix deposition, is not established. We conducted a retrospective cohort stud
Externí odkaz:
https://doaj.org/article/cb97ab287df94154846202d14a5e95f8
Autor:
Ivonne Nel, Carolin Münch, Saikal Shamkeeva, Mitja L. Heinemann, Berend Isermann, Bahriye Aktas
Publikováno v:
Diagnostics, Vol 13, Iss 24, p 3670 (2023)
Background: The “Liquid Biopsy” has become a powerful tool for cancer research during the last decade. Circulating cell-free DNA (cfDNA) that originates from tumors has emerged as one of the most promising analytes. In contrast to plasma-derived
Externí odkaz:
https://doaj.org/article/01896e1361f444a5a0f9e9df0ac1f934
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 7, p 208 (2022)
Background: Disseminated tumor cells (DTCs) in bone marrow aspirates of patients with primary breast cancer may serve as independent prognostic markers associated with impaired survival. Due to limited therapy options and high risk of recurrence part
Externí odkaz:
https://doaj.org/article/4fa5e621b0a047ef804b4113f50e84ba
Autor:
Anke Schlüter, Patrick Weller, Oliver Kanaan, Ivonne Nel, Lukas Heusgen, Benedikt Höing, Pia Haßkamp, Sebastian Zander, Magis Mandapathil, Nina Dominas, Judith Arnolds, Boris A. Stuck, Stephan Lang, Agnes Bankfalvi, Sven Brandau
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Patients suffering from squamous cell carcinoma of the larynx (LSCC) with lymphatic metastasis have a relatively poor prognosis and often require radical therapeutic management. The mechanisms which drive metastasis to the lymph n
Externí odkaz:
https://doaj.org/article/c714c62e803c4494b6d19fb9807a7376
Autor:
Ivonne Nel, Thomas C Gauler, Kira Bublitz, Lazaros Lazaridis, André Goergens, Bernd Giebel, Martin Schuler, Andreas-Claudius Hoffmann
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153018 (2016)
PURPOSE:Due to their minimal-invasive yet potentially current character circulating tumor cells (CTC) might be useful as a "liquid biopsy" in solid tumors. However, successful application in metastatic renal cell carcinoma (mRCC) has been very limite
Externí odkaz:
https://doaj.org/article/04022db292e54bfeaf9aad293d4530a3
Autor:
Patrick Weller, Ivonne Nel, Philipp Hassenkamp, Thomas Gauler, Anke Schlueter, Stephan Lang, Paulette Dountsop, Andreas-Claudius Hoffmann, Götz Lehnerdt
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113706 (2014)
BACKGROUND:Since image based diagnostic tools fail to detect early metastasis in head and neck squamous cell carcinoma (HNSCC) it is crucial to develop minimal invasive diagnostic methods. A promising approach is to identify and characterize circulat
Externí odkaz:
https://doaj.org/article/ec098fdb25c1400990d96689f5b457ea
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 568
Volume 15
Issue 3
Pages: 568
Background: Patients with hormone-receptor-positive (HR+) breast cancer are at increased risk for late recurrence. One reason might be disseminated tumor cells (DTCs), which split off in the early stages of the disease and metastasize into the bone m
Publikováno v:
Cancer Research. 82:P1-03
Background: All initial therapeutic decisions in early breast cancer are commonly based on the expression profiles of estrogen (ER), progesterone (PR) and the human epidermal growth factor 2 (HER2) receptors. However, breast cancer is a very heteroge
Publikováno v:
Cancers; Volume 14; Issue 17; Pages: 4101
In breast cancer, the genetic profiling of circulating cell-free DNA (cfDNA) from blood plasma was shown to have good potential for clinical use. In contrast, only a few studies were performed investigating urinary cfDNA. In this pilot study, we anal
Autor:
Carolin Münch, Saikal Shamkeeva, Mitja Heinemann, Berend Isermann, Sabine Kasimir-Bauer, Bahriye Aktas, Ivonne Nel
Publikováno v:
Cancer Research. 83:6693-6693
Background: The so-called “liquid biopsy” has become a powerful tool for cancer research in the recent years, with circulating cell-free DNA (cfDNA) that originates from tumors as one of the most promising analytes. In contrast to plasma derived