Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Ivonne M. C. M. Rietjens"'
Autor:
Haomiao Wang, Sjef Boeren, Wouter Bakker, Ivonne M. C. M. Rietjens, Edoardo Saccenti, Liang Zheng
Publikováno v:
npj Science of Food, Vol 8, Iss 1, Pp 1-16 (2024)
Abstract This study aimed to highlight the molecular and biochemical changes induced by methylglyoxal (MGO) exposure in SH-SY5Y human neuroblastoma cells, and to explore how these changes contribute to its neurotoxicity, utilizing an integrated prote
Externí odkaz:
https://doaj.org/article/3e5ae6e50ff64b4b8d5e9f5b3c0d0b32
Publikováno v:
npj Science of Food, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract This study aimed to evaluate human neurotoxicity and genotoxicity risks from dietary and endogenous methylglyoxal (MGO), utilizing physiologically based kinetic (PBK) modeling-facilitated reverse dosimetry as a new approach methodology (NAM)
Externí odkaz:
https://doaj.org/article/f93960b95b5c4e1bb10e42887bd371cd
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Over 1,000 pyrrolizidine alkaloids (PAs) and their N-oxides (PA-N-oxides) occur in 3% of all flowering plants. PA-N-oxides are toxic when reduced to their parent PAs, which are bioactivated into pyrrole intermediates that generate protein- and DNA-ad
Externí odkaz:
https://doaj.org/article/63f7fb95d1a64398938a6ffc22f9263f
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2658 (2023)
The composition, viability and metabolic functionality of intestinal microbiota play an important role in human health and disease. Studies on intestinal microbiota are often based on fecal samples, because these can be sampled in a non-invasive way,
Externí odkaz:
https://doaj.org/article/95044b564c0c4100b568a2e600751af9
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1544 (2023)
Purpurin is a major anthraquinone present in the roots of Rubia cordifolia (madder). Purpurin is known to activate Nrf2 (Nuclear transcription factor erythroid 2-related factor 2) EpRE (electrophile responsive element) mediated gene expression as a p
Externí odkaz:
https://doaj.org/article/382401b0b7754ea4a1efc052efe60a49
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
(-)-Epicatechin (EC) is one of the most popular polyphenols present in various food products in daily life. Upon intake, it is intensively metabolized by microbiota in the large intestine. In the present study, intra- and inter-individual variations
Externí odkaz:
https://doaj.org/article/9990b8ac7ee54284a3029d030082ecbb
Autor:
Mebrahtom Gebrelibanos Hiben, Laura de Haan, Bert Spenkelink, Sebastiaan Wesseling, Jacques Vervoort, Ivonne M. C. M. Rietjens
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background The health benefits of botanicals is linked to their phytochemicals that often exert pleiotropic effects via targeting multiple molecular signaling pathways such as the peroxisome proliferator-activated receptors (PPARs) and the n
Externí odkaz:
https://doaj.org/article/d609817e58924b9f96099135efd6df99
Publikováno v:
Journal of Ethnic Foods, Vol 6, Iss 1, Pp 1-8 (2019)
Abstract Background Wild edible plants are valuable resources for improving food and nutritional security. Besides, they may provide important health benefits since the health-promoting components of plant-based foods usually exist at higher levels i
Externí odkaz:
https://doaj.org/article/598c0deab3d74e4bbd973f06fbb18b03
Publikováno v:
Toxins, Vol 14, Iss 3, p 199 (2022)
In order to evaluate the potential differences between 3-Ac-DON and 15-Ac-DON in the human intestinal microbial metabolism, human fecal samples were anaerobically cultured in vitro. Quantitative fecal microbiota characteristics were obtained by 16S r
Externí odkaz:
https://doaj.org/article/6d75a9095979491e8faad5d48c752322
Autor:
Ashraf Abdelkhaliq, Meike van der Zande, Ans Punt, Richard Helsdingen, Sjef Boeren, Jacques J. M. Vervoort, Ivonne M. C. M. Rietjens, Hans Bouwmeester
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Upon ingestion, nanoparticles can interact with the intestinal epithelial barrier potentially resulting in systemic uptake of nanoparticles. Nanoparticle properties have been described to influence the protein corona formation and
Externí odkaz:
https://doaj.org/article/c017b77a57de4b5ab731a9f29856a460