Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ivonne, Naumann"'
Autor:
Michael Strupp, Grant C. Churchill, Ivonne Naumann, Ulrich Mansmann, Amani Al Tawil, Anastasia Golentsova, Nicolina Goldschagg
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundBetahistine was registered in Europe in the 1970s and approved in more than 80 countries as a first-line treatment for Menière's disease. It has been administered to more than 150 million patients. However, according to a Cochrane systemat
Externí odkaz:
https://doaj.org/article/461639fe2ac04f599647a45524256226
Autor:
Simone Fulda, Klaus-Michael Debatin, Daniela Bertele, Maxi Schneider, Ivonne Naumann, Daniela Opel
Purpose: Because we recently identified Akt activation as a novel poor prognostic indicator in neuroblastoma, we investigated whether phosphoinositide 3′-kinase (PI3K) inhibition sensitizes neuroblastoma cells for TRAIL-induced apoptosis.Experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40db9ecebe8b02dd0444b40775cc7a49
https://doi.org/10.1158/1078-0432.c.6518233.v1
https://doi.org/10.1158/1078-0432.c.6518233.v1
Supplementary Figures S1-S4; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a83242a7ef16c451d0a03c3f77827f
https://doi.org/10.1158/1078-0432.22441258.v1
https://doi.org/10.1158/1078-0432.22441258.v1
Purpose: Searching for novel strategies to modulate apoptosis in neuroblastoma, we investigated the potential of the proteasome inhibitor bortezomib.Experimental Design: The effect of bortezomib on TRAIL (TNF-related apoptosis-inducing ligand)-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12a4b3415becdfe97748942c799ea63
https://doi.org/10.1158/1078-0432.c.6518371
https://doi.org/10.1158/1078-0432.c.6518371
Autor:
Simone Fulda, Klaus-Michael Debatin, Daniela Bertele, Maxi Schneider, Ivonne Naumann, Daniela Opel
Supplementary Figures S1-S5; Supplementary Materials and Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646b61a8101770030945c40984065148
https://doi.org/10.1158/1078-0432.22441051.v1
https://doi.org/10.1158/1078-0432.22441051.v1
Autor:
Diana Marklein, Ulrike Graab, Ivonne Naumann, Tiandong Yan, Rosalie Ridzewski, Frauke Nitzki, Albert Rosenberger, Kai Dittmann, Jürgen Wienands, Leszek Wojnowski, Simone Fulda, Heidi Hahn
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52898 (2012)
We searched for a drug capable of sensitization of sarcoma cells to doxorubicin (DOX). We report that the dual PI3K/mTOR inhibitor PI103 enhances the efficacy of DOX in several sarcoma cell lines and interacts with DOX in the induction of apoptosis.
Externí odkaz:
https://doaj.org/article/020fc499aaa144d3854f585b67f7895b
Autor:
Kristina Hauer, Günther H.S. Richter, Thomas G. P. Grunewald, Ivonne Naumann, Sabine Rössler, Simone Fulda, Martin S. Staege, Stefan Burdach, Colette Berns, Irene Esposito, Annette Fasan
Publikováno v:
The Journal of Pathology. 230:70-81
Metastatic spread in Ewing sarcomas (ES) is frequent and haematogenous. G-protein coupled receptor 64 (GPR64), an orphan receptor with normal expression restricted to human epididymis is specifically over-expressed in ES among sarcoma, but also up-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287d611a6fb97710751a79b307c01769
https://doi.org/10.1002/path.4170
https://doi.org/10.1002/path.4170
Autor:
Wolfgang Nachbauer, Ilaria Giordano, Ingrid Berger, Jens Claassen, Christine Adrion, Ivonne Naumann, Otmar Bayer, Thomas Klopstock, Ulrich Mansmann, Bart P.C. van de Warrenburg, Thomas Klockgether, Claudia Stendel, Katharina Feil, Heike Jacobi, Julian Teufel, Michael Strupp, Sylvia Bösch, Hans-Helge Müller, Ludger Schöls, Holger Hengel, Ellen Uslar
Publikováno v:
BMC Neurology
BMC Neurology, 17, 7
BMC neurology 17(1), 7 (2017). doi:10.1186/s12883-016-0786-x
BMC Neurology, 17, 1, pp. 7
BMC Neurology, 17, 7
BMC neurology 17(1), 7 (2017). doi:10.1186/s12883-016-0786-x
BMC Neurology, 17, 1, pp. 7
Cerebellar ataxia (CA) is a frequent and often disabling condition that impairs motor functioning and impacts on quality of life (QoL). No medication has yet been proven effective for the symptomatic or even causative treatment of hereditary or non-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353436a27b7732aec3d7b06a70edd90b
https://pubmed.ncbi.nlm.nih.gov/28068987
https://pubmed.ncbi.nlm.nih.gov/28068987
Autor:
Barbara C, Klein, Sebastian J, Bartel, Kai H, Darsow, Ivonne, Naumann, Christian, Walter, Rainer, Buchholz, Harald A, Lange
Publikováno v:
Journal of phycology. 47(3)
Antioxidant agents from natural sources are currently the focus of scientific interest and are part of several natural product screenings. Coenzymes Q (CoQ, ubiquinones) are integral parts of the electron transport chain of the inner mitochondrial me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f598b1d7bcd6eb7f01452a9580aac7a
https://pubmed.ncbi.nlm.nih.gov/27021998
https://pubmed.ncbi.nlm.nih.gov/27021998
Autor:
Kai H. Darsow, Ivonne Naumann, Barbara C. Klein, Rainer Buchholz, Harald A. Lange, Sebastian Bartel
Publikováno v:
Rapid Communications in Mass Spectrometry. 25:2517-2523
The pharmaceutical industry is interested in identifying novel target compounds. Due to their versatile pharmacological activities (e.g. antiviral, anti-carcinogen and immunosuppressive) sulfoquinovosyldiacylglycerides (SQDGs) are potential drug cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961bc8e1ecd540c92794a85a79f27c3e
https://doi.org/10.1002/rcm.5137
https://doi.org/10.1002/rcm.5137