Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ivona T. Olszak"'
Autor:
David T. Scadden, Byeong-Chel Lee, Ivona T. Olszak, Daniel A. Haber, Julie Hancock, David Dombkowski, Eyal C. Attar, Nobuyuki Miura, Andrew D. Luster, Sean Bong Lee, Yoriko Saito, Douglas P. Olson, Peter S. Choi, Gregor B. Adams, Tao Cheng
Publikováno v:
Genes & Development. 17:1592-1604
Hematopoiesis in mammals undergoes a developmental shift in location from fetal liver to bone marrow accompanied by a gradual transition from highly proliferative to deeply quiescent stem cell populations. P2Y receptors are G-protein-coupled nucleoti
Autor:
Mark C. Poznansky, Ivona T. Olszak, Richard H. Evans, Zhengyu Wang, Russell B. Foxall, Douglas P. Olson, Kathryn Weibrecht, Andrew D. Luster, David T. Scadden
Publikováno v:
Journal of Clinical Investigation. 109:1101-1110
Autor:
Mark C. Poznansky, Ivona T. Olszak, Richard H. Evans, Martin R. Pollak, Douglas P. Olson, David T. Scadden, Edward M. Brown, Claudine H. Kos
Publikováno v:
Journal of Clinical Investigation. 105:1299-1305
Recruitment of macrophages to sites of cell death is critical for induction of an immunologic response. Calcium concentrations in extracellular fluids vary markedly, and are particularly high at sites of injury or infection. We hypothesized that extr
Autor:
David T. Scadden, Mark C. Poznansky, Richard H. Evans, Ivona T. Olszak, Andrew D. Luster, Russell B. Foxall
Publikováno v:
Nature Medicine. 6:543-548
Movement towards or away from a given stimulus guides the directional migration of prokaryotes, simple eukaryotes and neurons. As bi-directional cues may influence entry and exit of immune effector cells from tissue sites, we evaluated the migratory
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 83(10)
Chemotaxis or active movement of leukocytes toward a stimulus has been shown to occur in response to chemokinetic agents including members of the recently identified superfamily of proteins called chemokines. Leukocyte chemotaxis is thought to play a
Autor:
David T. Scadden, Anita H. Piascik, Gregor B. Adams, Richard H. Evans, Tao Cheng, Mark C. Poznansky, Ivona T. Olszak, Russell B. Foxall
Publikováno v:
Experimental hematology. 29(6)
Objective The translocation from fetal liver hematopoiesis to secondary organs occurs during the second trimester of human gestation. It has been hypothesized that stem cells migrate and acquire lineage potential based on cues specific to the adopted
Autor:
David T. Scadden, Tao Cheng, Zhijian Lu, Steven H. Herrmann, Ivona T. Olszak, Hongmei Shen, Eduardo A. Garcia-Zepeda, Robert Fallon, Andrew D. Luster
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 166(8)
The chemokine stroma-derived factor (SDF)-1, and its receptor, CXCR-4, have been shown to be essential for the translocation of hemopoietic stem cells from the fetal liver to the bone marrow (BM). We hypothesized that if CXCR-4 plays a crucial role i
Autor:
David T. Scadden, Karissa T. Chabner, Russell B. Foxall, Thomas H. Meyer, Spyros A. Kalams, Kelly E. Hartman, Christian Brander, Mark J. Pykett, Ivona T. Olszak, Anita H. Piascik, Richard H. Evans, Mark C. Poznansky, Michael Rosenzweig
Publikováno v:
Nature biotechnology. 18(7)
Biocompatible inorganic matrices have been used to enhance bone repair by integrating with endogenous bone architecture. Hypothesizing that a three-dimensional framework might support reconstruction of other tissues as well, we assessed the capacity
Autor:
Ivona T. Olszak, Sarah Turner, Gregor B. Adams, Myra O. McClure, Mark C. Poznansky, Madeleine C. McMullen, David T. Scadden
Publikováno v:
Journal of acquired immune deficiency syndromes (1999). 21(1)
A proposed hemopoietic stem cell gene therapy for treatment for HIV infection would involve transduction of CD34+ hemopoietic stem cells with vectors encoding anti-HIV constructs. Peripheral blood has proved to be a useful source of these hemopoietic