Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ivona Hančlová"'
Autor:
Jiří Jiráček, Miloš Buděšínský, Miloslav Sanda, Pavel Fiedler, Ivona Hančlová, Jan Pícha, Václav Vaněk
Publikováno v:
Tetrahedron. 65:6090-6103
In the present work, we describe in detail an efficient solution synthesis of norleucine-derived phosphonopeptides mimicking the peptide sequences Nle-Gly(Ala) and Nle-Gly(Ala)-Val. The most efficient strategy involved use of the benzyl group. The sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e20c3ca45bc563a84170719b74fadd
https://doi.org/10.1016/j.tet.2009.05.051
https://doi.org/10.1016/j.tet.2009.05.051
Autor:
Lenka Zakova, Milos Budesínský, Ludmila Kazdova, Miloslav Sanda, Eva Protivinska, Jiri Jiracek, Ivona Hančlová
Publikováno v:
Biochemistry. 47:5858-5868
In this study, we prepared several shortened and full-length insulin analogues with substitutions at position B26. We compared the binding affinities of the analogues for rat adipose membranes with their ability to lower the plasma glucose level in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99a8a7479ab9f7bad7248b515a7b78f
https://doi.org/10.1021/bi702086w
https://doi.org/10.1021/bi702086w
Publikováno v:
Tetrahedron Letters. 49:5629-5631
We present herein a straightforward synthesis of N -Fmoc-protected synthons derived from a phosphinic analogue of methionine. These precursors were used successfully for the solid-phase synthesis of methionine-mimic phosphinopeptides using BOP-cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577871d1c83bb64eab5db7ca3d3c9d0d
https://doi.org/10.1016/j.tetlet.2008.07.062
https://doi.org/10.1016/j.tetlet.2008.07.062
Autor:
Milos Budesínský, Vaclav Vanek, Ivona Hančlová, Markos Koutmos, Miloslav Sanda, Ivan Rosenberg, Jiri Brynda, Jana Mládková, Petra Kabeleová, Timothy A. Garrow, Jiri Jiracek, Milan Kozisek
Publikováno v:
Journal of medicinal chemistry. 52(12)
Betaine-homocysteine S-methyltransferase (BHMT) catalyzes the transfer of a methyl group from betaine to l-homocysteine, yielding dimethylglycine and l-methionine. In this study, we prepared a new series of BHMT inhibitors. The inhibitors were design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0f22e380dc5336ea6cebabbdf54ba3
https://pubmed.ncbi.nlm.nih.gov/19534555
https://pubmed.ncbi.nlm.nih.gov/19534555
Autor:
Miloslav Sanda, Daniel Zyka, Andrzej M. Brzozowski, Jan Ježek, Lenka Žáková, Ivona Hančlová, Jiří Jiráček
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 13(5)
In this paper, we present the detailed synthetic protocol and characterization of Fmoc-Lys(Pac)-OH, its use for the preparation of octapeptides H-Gly-Phe-Tyr-N-MePhe-Thr-Lys(Pac)-Pro-Thr-OH and H-Gly-Phe-Phe-His-Thr-Pro-Lys(Pac)-Thr-OH by solid-phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37019fc0b966b894ab22e38e7ae4c4e1
https://pubmed.ncbi.nlm.nih.gov/17436342
https://pubmed.ncbi.nlm.nih.gov/17436342
Autor:
Václav Vaněk, Miloš Buděšínský, Petra Kabeleová, Miloslav Šanda, Milan Kožíšek, Ivona Hančlová, Jana Mládková, Jiří Brynda, Ivan Rosenberg, Markos Koutmos, Timothy A. Garrow, Jiří Jiráček
Publikováno v:
Journal of Medicinal Chemistry; Jun2009, Vol. 52 Issue 12, p3652-3665, 14p