Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ivo P van de Peppel"'
Autor:
Hoi W. Wu, Ivo P. Van de Peppel, Julie W. Rutten, J. Wouter Jukema, Emmelien Aten, Ingrid M. Jazet, Tamara T. Koopmann, Daniela Q. C. M. Barge-Schaapveld, Nina Ajmone Marsan
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 11, Iss 3, p 86 (2024)
Mutations in the LMNA-gene can cause a variety of ‘laminopathies’. These laminopathies are associated with a range of phenotypes, including disorders affecting the adipose tissue, peripheral nerves, the heart, such as dilated cardiomyopathy and c
Externí odkaz:
https://doaj.org/article/7b2661c41f3e4d7c917a28c9fadb7283
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/4e000804aa8c4eea8990986f9f37ec82
Autor:
Cristy R.C. Verzijl, Ivo P. van de Peppel, Roos E. Eilers, Vincent W. Bloks, Justina C. Wolters, Martijn Koehorst, Niels J. Kloosterhuis, Rick Havinga, Mathilde Jalving, Dicky Struik, Johan W. Jonker
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114270- (2023)
The RAS-MAPK signaling pathway is one of the most frequently dysregulated pathways in human cancer. Small molecule inhibitors directed against this pathway have clinical activity in patients with various cancer types and can improve patient outcomes.
Externí odkaz:
https://doaj.org/article/608ee46f4cd848a994c092ece029b800
Autor:
Ivo P. van de Peppel, Anna Bertolini, Theo H. van Dijk, Albert K. Groen, Johan W. Jonker, Henkjan J. Verkade
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1562-1572 (2019)
Transintestinal cholesterol excretion (TICE) is a major route for eliminating cholesterol from the body and a potential therapeutic target for hypercholesterolemia. The underlying mechanism, however, is largely unclear, and its contribution to choles
Externí odkaz:
https://doaj.org/article/981e13cd35934e3b9f41e82dcafc4319
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Non-alcoholic fatty liver disease (NAFLD) or metabolic (dysfunction) associated liver disease (MAFLD), is, with a global prevalence of 25%, the most common liver disorder worldwide. NAFLD comprises a spectrum of liver disorders ranging from simple st
Externí odkaz:
https://doaj.org/article/5d12fd4abeac4241be543e3792e96a39
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Non-alcoholic fatty liver disease (NAFLD) is a major growing worldwide health problem. We previously reported that interruption of the enterohepatic circulation of bile acids using a non-absorbable apical sodium-dependent bile acid transporter inhibi
Externí odkaz:
https://doaj.org/article/1345c9e4115d4a459454d761cc73e0a9
Publikováno v:
Expert opinion on investigational drugs, 29(2), 1-9. Taylor & Francis Ltd
Introduction: Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and is strongly associated with obesity and insulin resistance. NAFLD refers to a spectrum of disorders ranging from asymptomatic hepatic steatosis (non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7937c2b05feca435096f3f2242a5b671
https://doi.org/10.1080/13543784.2020.1708898
https://doi.org/10.1080/13543784.2020.1708898
Autor:
Theo H. van Dijk, Anna Bertolini, Albert K. Groen, Henkjan J. Verkade, Johan W. Jonker, Ivo P van de Peppel
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1562-1572 (2019)
Journal of Lipid Research, 60(9), 1562-1572. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of lipid research, 60(9), 1562-1572. American Society for Biochemistry and Molecular Biology Inc.
J Lipid Res
Journal of Lipid Research, 60(9), 1562-1572. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of lipid research, 60(9), 1562-1572. American Society for Biochemistry and Molecular Biology Inc.
J Lipid Res
Transintestinal cholesterol excretion (TICE) is a major route for eliminating cholesterol from the body and a potential therapeutic target for hypercholesterolemia. The underlying mechanism, however, is largely unclear, and its contribution to choles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734da4eecc9690a38ef9c96adccdea15
http://www.sciencedirect.com/science/article/pii/S002222752032318X
http://www.sciencedirect.com/science/article/pii/S002222752032318X
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology, Vol 11 (2021)
Non-alcoholic fatty liver disease (NAFLD) or metabolic (dysfunction) associated liver disease (MAFLD), is, with a global prevalence of 25%, the most common liver disorder worldwide. NAFLD comprises a spectrum of liver disorders ranging from simple st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76ff8dcd6bb3b432d96bb3c6f526822
https://doi.org/10.3389/fendo.2020.601627
https://doi.org/10.3389/fendo.2020.601627
Autor:
Ales Dvorak, Ivo P van de Peppel, Nikola Capková, Libor Vítek, Henkjan J. Verkade, Maaike Blankestijn, Johan W. Jonker
Publikováno v:
Pediatric Research, 89. Nature Publishing Group
Background: Unconjugated hyperbilirubinemia, a feature of neonatal jaundice or Crigler-Najjar syndrome, can lead to neurotoxicity and even death. We previously demonstrated that unconjugated bilirubin (UCB) can be eliminated via transintestinal excre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa1101f112395d9ac24c04f97972868
https://doi.org/10.1038/s41390-020-0926-2
https://doi.org/10.1038/s41390-020-0926-2