Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ivo Durník"'
Publikováno v:
Journal of Chemical Information and Modeling. 61:6000-6011
Mismatched base pairs alter the flexibility and intrinsic curvature of DNA. The role of such DNA features is not fully understood in the mismatch repair pathway. MutS/DNA complexes exhibit DNA bending, PHE intercalation, and changes of base-pair para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac839574df2244aa5565afd6f37038c6
https://doi.org/10.1021/acs.jcim.1c00731
https://doi.org/10.1021/acs.jcim.1c00731
Autor:
Ivo Durník, Andrea Čablová, Aneta Hromádková, Josef Tomeček, Lenka Dastychová, Michal Rouchal, Radek Marek, Jan Novotný, Zdeňka Prucková, Robert Vícha, Petr Kulhánek
Publikováno v:
The Journal of Organic Chemistry. 86:4483-4496
Multitopic supramolecular guests with finely tuned affinities toward widely explored cucurbit[n]urils (CBs) and cyclodextrins (CDs) have been recently designed and tested as functional components of advanced supramolecular systems. We employed variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edb5de7aedb04bcb0298d46c99a6c98
https://doi.org/10.1021/acs.joc.0c02917
https://doi.org/10.1021/acs.joc.0c02917
Publikováno v:
Journal of Chemical Information and Modeling. 61:211-222
The formation of purine and pyrimidine base pairs (BPs), which contributes to shaping of the canonical and noncanonical 3D structures of nucleic acids, is one the most investigated phenomena in chemistry and life sciences. In this contribution, the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff1c75215bca2751b1bd74210dc901d
https://doi.org/10.1021/acs.jcim.0c00642
https://doi.org/10.1021/acs.jcim.0c00642
Publikováno v:
Nucleic Acids Research
Mismatch repair is a highly conserved cellular pathway responsible for repairing mismatched dsDNA. Errors are detected by the MutS enzyme, which most likely senses altered mechanical property of damaged dsDNA rather than a specific molecular pattern.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f9ffdcf95e8568b7863b2785b393b4
http://europepmc.org/articles/PMC7672436
http://europepmc.org/articles/PMC7672436
Publikováno v:
Nucleic Acids Research
Several sequences forming G-quadruplex are highly conserved in regulatory regions of genomes of different organisms and affect various biological processes like gene expression. Diverse G-quadruplex properties can be modulated via their interaction w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8e81350b60d5ca0c5afaca512bd380