BRCA Testing by Single-Molecule Molecular Inversion Probes

Autor: Alwin Rikken, Bart van Lier, Dimitra Zafeiropoulou, Alexander Hoischen, Ivo B J F Adan, Ronny Derks, Marcel R. Nelen, Stijn M M Bertens, Kornelia Neveling, Djie Tjwan Thung, Marloes Steehouwer, Michael Kwint, Jay Shendure, Hicham Ouchene, Evan A. Boyle, Arjen R. Mensenkamp, Jayne Y. Hehir-Kwa, Stefan H. Lelieveld, Tomasz Stokowy, Steven Castelein, Tom Hofste, Per M. Knappskog, Astrid Eijkelenboom, Beth Martin, Ermanno A.J. Bosgoed, Vidar M. Steen, Helger G. Yntema, Marjolijn J. L. Ligtenberg, Bastiaan B J Tops, Hildegunn Høberg-Vetti, Marloes Tychon

Publikováno v: Clinical Chemistry, 63, 503-512
Clinical Chemistry, 63(2), 503-512. American Association for Clinical Chemistry Inc.
Clinical Chemistry, 63, 2, pp. 503-512

BACKGROUND Despite advances in next generation DNA sequencing (NGS), NGS-based single gene tests for diagnostic purposes require improvements in terms of completeness, quality, speed, and cost. Single-molecule molecular inversion probes (smMIPs) are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff362a16b1977a0fc949eda67975675
https://doi.org/10.1373/clinchem.2016.263897