Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Ivo Amende"'
Autor:
Ivo Amende, Thomas G. Hampton
Publikováno v:
Journal of Motor Behavior. 42:1-4
Guillot, Asress, Richardson, Glass, and Miller (2008) recently reported that treadmill gait analysis does not detect motor deficits in animal models of Parkinson's disease (PD) or amyotrophic lateral sclerosis (ALS). The authors studied aged C57BL/6J
Functional testing in a mouse stroke model induced by occlusion of the distal middle cerebral artery
Autor:
Judith, Lubjuhn, Alexandra, Gastens, Gertrud, von Wilpert, Panagiotis, Bargiotas, Oliver, Herrmann, Sasidhar, Murikinati, Tamer, Rabie, Hugo H, Marti, Hugo, Marti, Ivo, Amende, Tom G, Hampton, Markus, Schwaninger
Publikováno v:
Journal of Neuroscience Methods. 184:95-103
Reducing post-stroke disability is the major goal of stroke therapy. Consequently, functional testing is essential in experimental stroke studies to increase the predictive value of animal models. We used several sensory and motor tests to assess fun
Autor:
Thomas G. Hampton, James P. Morgan, Jiang-Yong Min, Sohail Malek, Ivo Amende, Ju-Feng Wang, Walter H. Abelmann, John Zeind, Alan I. Green, Xinhua Yan
Publikováno v:
European Journal of Pharmacology. 592:123-127
Clozapine, an atypical antipsychotic, is very effective in the treatment of resistant schizophrenia. However, cardiotoxicity of clozapine, particularly in young patients, has raised concerns about its safety. Increased catecholamines have been postul
Autor:
Achim Meissner, Ju-Feng Wang, Yu Chen, Ivo Amende, Qingen Ke, Sohail Malek, Thomas G. Hampton, Victor Chu, Walter H. Abelmann, Jielin Zhang, James P. Morgan, Clyde S. Crumpacker
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 289:H1577-H1583
Recent studies point to important interactions between proinflammatory cytokines and neurohumoral mediators in heart failure. Here we investigate the influence of the β-adrenergic system on cytokines and neurohumoral factors and the sequelae of vira
Autor:
Jiang-Yong Min, Guifu Wu, Sohail Malek, Yong-Fu Xiao, Thomas G. Hampton, Yu Chen, Ivo Amende, James P. Morgan, Qingen Ke, Emel Kaplan
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H2323-H2331
Cocaine treatment of mice with viral myocarditis significantly increases neutrophil infiltration into the myocardium and exacerbates the inflammatory response. The mechanisms of these effects are unknown; however, it may be that cocaine increases cir
Publikováno v:
Physiology & Behavior. 82:381-389
The segmentally trisomic mouse Ts65Dn is a model of Down syndrome (DS). Gait abnormalities are almost universal in persons with DS. We applied a noninvasive imaging method to quantitatively compare the gait dynamics of Ts65Dn mice (n=10) to their eup
Autor:
Eric S. Bachman, James P. Morgan, Ivo Amende, Harveen Dhillon, Ju-Feng Wang, Thomas G. Hampton, Anthony N. Hollenberg
Publikováno v:
Endocrinology. 145:2767-2774
Hyperthyroidism and states of adrenergic hyperactivity have many common clinical features, suggesting similar pathogenic mechanisms of action. The widespread use of beta-adrenergic receptor (betaAR) antagonists (beta-blockers) to treat hyperthyroidis
Autor:
Peter Mueller, Thomas G. Hampton, Jose M. Otero, Ivo Amende, Ajit Kale, Victor Chu, Katrina Piskorski
Publikováno v:
Alternatives to Laboratory Animals. 32:195-201
Linking gene defect to disease phenotypes in mice has become an essential step in the development of new drugs. Yet, many in vitro and in vivo assays require anaesthetic and surgery or do not reflect physiologically relevant phenomena. The effects of
Autor:
Joseph P. DeAngelis, Thomas G. Hampton, Kenneth D. Philipson, James P. Morgan, Ju-Feng Wang, Ivo Amende
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 279:H2846-H2854
Enhanced gene expression of the Na+/Ca2+exchanger in failing hearts may be a compensatory mechanism to promote influx and efflux of Ca2+, despite impairment of the sarcoplasmic reticulum (SR). To explore this, we monitored intracellular calcium (Cai
Publikováno v:
American Heart Journal. 137:368-371
Background Intravascular ultrasound (IVUS) imaging can be used to optimize implantation of intracoronary stents; the variability of the measurements, however, remains unclear. Our aim in this study was to determine the intraobserver and interobserver