Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ivo, Palásek"'
Publikováno v:
Leukemia. 23:793-796
Acute myeloid leukemia (AML) is a heterogeneous group of diseases affecting hematopoietic stem cells. In recent years, several novel molecular abnormalities have been identified in patients with AML, particularly in cases with normal karyotype. Among
Autor:
Doubek M, Dana Dvorakova, Jitka Berkovcová, Ivo Palásek, Yvona Brychtová, Marta Krejčí, Jiří Mayer
Publikováno v:
Leukemia. 19:885-888
Acute myeloid leukemias with recurrent genetic abnormalities: frequent assessment of minimal residual disease and treatment of molecular relapse with chemotherapy
Autor:
Ivo Palásek, Zdenek Racil, Dana Dvorakova, Jiri Mayer, Ivana Jeziskova, Filip Rázga, Martina Lengerová, Markéta Protivánková
Publikováno v:
American journal of hematology. 85(12)
Nucleophosmin (NPM1) mutations in exon 12 are the most common genetic alternation in cytogenetically normal AML (CN-AML). Although mutation types A, B, and D represent the majority of cases, rare mutation variants of the NPM1 gene in individual patie
Autor:
Michaela, Pevná, Petr, Vondrácek, Ivo, Palásek, Milos, Kerkovský, Zdenĕk, Korístek, Milan, Navrátil, Martin, Klabusay
Publikováno v:
Casopis lekaru ceskych. 149(4)
Toxoplasmosis is a rare opportunistic protozoal infection, which may occur in patients after hematopoietic stem cell transplantation. This disease originates almost exclusively from reactivation of latent infection in seropositive recipients. We pres
Autor:
Martin Klabusay, Ivo Palásek, Marta Krejčí, Marek Borsky, Ivana Jeziskova, Dana Dvorakova, Jiri Mayer, Michael Doubek, Zdenek Pospisil, Yvona Brychtová, Tomáš Jurček
Publikováno v:
Experimental hematology. 37(6)
Objective Our objective was to determine the value of frequent minimal residual disease (MRD) monitoring in acute myeloid leukemia (AML) as a robust marker of impending relapse, and whether treatment benefits patients during the MRD-positive phase of
Autor:
Zdenek Racil, Ivo Palásek, Martina Lengerová, Ivana Jeziskova, Jiri Mayer, Markéta Protivánková, Dana Dvorakova
Publikováno v:
Blood. 114:4672-4672
Abstract 4672 Background Mutations within NPM1 gene occurs in about 60% of adult cytogenetic normal AML (CN-AML) and represent the single most frequent molecular aberration in this subgroups of patients. These mutations usually occur at exon 12 and i
Autor:
Dana Dvorakova, Marek Borsky, Yvona Brychtová, Sona Struncova, Jiri Mayer, Michael Doubek, Martin Klabusay, Zdenek Pospisil, Ivo Palásek, Marta Krejčí
Publikováno v:
Blood. 110:4356-4356
Background. It seems that the population of leukemia stem cells (LSCs) have fundamental importance in the origin and maintenance of the acute myeloid leukaemia (AML). Eradication of LSCs is a new goal of AML therapy. We hypothesized, that by monitori