Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ivka Afrikanova"'
Autor:
Avital Gilam, Chen Hainan, Yin Zhang, Qi Zheng, Kong Ling-Jie, Mi Shi, Ruby Yanru Chen-Tsai, Zoya Gluzman, Jinling Li, Ivka Afrikanova, Ruhong Jiang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Hemophilia A is a monogenic disease with a blood clotting factor VIII (FVIII) deficiency caused by mutation in the factor VIII (F8) gene. Current and emerging treatments such as FVIII protein injection and gene therapies via AAV-delivered F8 transgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4e0eb869329515b61f91c0067e341a
http://link.springer.com/article/10.1038/s41598-019-53198-y
http://link.springer.com/article/10.1038/s41598-019-53198-y
Autor:
Anthony M.P. Montgomery, Mayra Yebra, Megan Simpkinson, Alberto Hayek, Ivka Afrikanova, Yang Xu
Publikováno v:
Journal of Biological Chemistry. 286:36042-36052
Stepwise approaches for the derivation of β-cells from human embryonic stem cells have been described. However, low levels of endocrine specification limit the final yield of insulin-producing β-cells. In this study, we show that the pyrrolo-pyrimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8fba47888448b3ab1a0afff454340de
https://doi.org/10.1074/jbc.m111.290825
https://doi.org/10.1074/jbc.m111.290825
Publikováno v:
Journal of General Virology. 80:333-339
In rotavirus-infected cells, the non-structural proteins NSP5 and NSP2 localize in complexes called viroplasms, where replication and assembly occur. Recently, we have demonstrated direct interaction of NSP5 with NSP2, and as a consequence of that, u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea791b7066d899376aaaea4fba7004c
https://doi.org/10.1099/0022-1317-80-2-333
https://doi.org/10.1099/0022-1317-80-2-333
Publikováno v:
Journal of General Virology. 79:2679-2686
We have previously shown that a number of isoforms of the non-structural rotavirus protein NSP5 are found in virus-infected cells. These isoforms differ in their level of phosphorylation which, at least in part, appears to occur through autophosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5a4cb2cb379bc2d6b4aeba904d2590
https://doi.org/10.1099/0022-1317-79-11-2679
https://doi.org/10.1099/0022-1317-79-11-2679
Publikováno v:
Journal of General Virology. 77:2059-2065
NSP5 (non-structural protein 5) is one of two proteins encoded by genome segment 11 of group A rotaviruses. In virus-infected cells NSP5 accumulates in the virosomes and is found as two polypeptides with molecular masses of 26 and 28 kDa (26K and 28K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166cbc634da416bfca24fa94abd036d0
https://doi.org/10.1099/0022-1317-77-9-2059
https://doi.org/10.1099/0022-1317-77-9-2059
Autor:
G. Adam Jones, Andrew Hinton, Gary B. Fogel, Ivka Afrikanova, Alberto Hayek, Charles C. King, Shaun Hunter, Ana D. Lopez
Publikováno v:
Stem cells (Dayton, Ohio). 32(9)
MicroRNAs (miRNAs) are noncoding, regulatory RNAs expressed dynamically during differentiation of human embryonic stem cells (hESCs) into defined lineages. Mapping developmental expression of miRNAs during transition from pluripotency to definitive e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1205b9d356494ae8f9ea45d3530949b9
https://pubmed.ncbi.nlm.nih.gov/24805944
https://pubmed.ncbi.nlm.nih.gov/24805944
Autor:
Michael A Wilson, Gene W. Yeo, Ivka Afrikanova, Alberto Hayek, Amy E. Pasquinelli, Brian N Maurer, Charles C. King, Andrew Hinton
Publikováno v:
Stem cells and development. 19(6)
Human embryonic stem cells (hESCs) have the potential to differentiate into many adult cell types, and they are being explored as a resource for cell replacement therapies for multiple diseases. In order to optimize in vitro differentiation protocols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a831791f94488d2c3f19e49f73db1e9
https://pubmed.ncbi.nlm.nih.gov/19807270
https://pubmed.ncbi.nlm.nih.gov/19807270