Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ivette Zelaya"'
Autor:
Noam Auslander, Daniel M Ramos, Ivette Zelaya, Hiren Karathia, Thomas O. Crawford, Alejandro A Schäffer, Charlotte J Sumner, Eytan Ruppin
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp 1-17 (2020)
Abstract Modifier genes are believed to account for the clinical variability observed in many Mendelian disorders, but their identification remains challenging due to the limited availability of genomics data from large patient cohorts. Here, we pres
Externí odkaz:
https://doaj.org/article/3de22a2ac37c4d438a901282d752a3e5
Autor:
Christine B Peterson, Susan K Service, Anna J Jasinska, Fuying Gao, Ivette Zelaya, Terri M Teshiba, Carrie E Bearden, Rita M Cantor, Victor I Reus, Gabriel Macaya, Carlos López-Jaramillo, Marina Bogomolov, Yoav Benjamini, Eleazar Eskin, Giovanni Coppola, Nelson B Freimer, Chiara Sabatti
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006046 (2016)
The observation that variants regulating gene expression (expression quantitative trait loci, eQTL) are at a high frequency among SNPs associated with complex traits has made the genome-wide characterization of gene expression an important tool in ge
Externí odkaz:
https://doaj.org/article/e88eac94de394585ae1f17fd1c91f020
Autor:
Thomas J Crisman, Ivette Zelaya, Dan R Laks, Yining Zhao, Riki Kawaguchi, Fuying Gao, Harley I Kornblum, Giovanni Coppola
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0164649 (2016)
We present here a novel genetic algorithm-based random forest (GARF) modeling technique that enables a reduction in the complexity of large gene disease signatures to highly accurate, greatly simplified gene panels. When applied to 803 glioblastoma m
Externí odkaz:
https://doaj.org/article/58ac77edf8f8459a931a15ad5660d5ef
Autor:
Thomas O. Crawford, Charlotte J. Sumner, Hiren Karathia, Ivette Zelaya, Eytan Ruppin, Alejandro A. Schäffer, Daniel M. Ramos, Noam Auslander
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp n/a-n/a (2020)
Molecular Systems Biology
Molecular Systems Biology
Modifier genes are believed to account for the clinical variability observed in many Mendelian disorders, but their identification remains challenging due to the limited availability of genomics data from large patient cohorts. Here, we present GENDU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71617bac4d6da8dd596eb01d64cfe3ee
https://doi.org/10.2139/ssrn.3517533
https://doi.org/10.2139/ssrn.3517533
Autor:
Matthew J. Jorgensen, Giovanni Coppola, Ken Dewar, George M. Weinstock, Emily S. W. Wong, Joseph DeYoung, Chiara Sabatti, Scott C. Fears, Wesley C. Warren, David J. Jentsch, Lynn A. Fairbanks, Richard K. Wilson, Christine B. Peterson, Nelson B. Freimer, Anna J. Jasinska, Eleazar Eskin, Jay R. Kaplan, Allison E. Furterer, John Blangero, Thomas D. Dyer, Ivette Zelaya, Diego Villar, Vasily Ramensky, Yu S. Huang, Oi Wa Choi, Rita M. Cantor, Hannes Svardal, Roger P. Woods, Marina Bogomolov, Christopher A. Schmitt, Bronwen Aken, Yoav Benjamini, Rishi Nag, Paul Flicek
Publikováno v:
Nature genetics
Nature genetics, vol 49, iss 12
Nature genetics, vol 49, iss 12
By analyzing multi-tissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, we generated a transcriptome resource and produced the first catalogue of expression quantitative trait loci (eQTLs) in a non-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447c3d987e2ad777f4d5215ac4444270
http://europepmc.org/articles/PMC5714271
http://europepmc.org/articles/PMC5714271
Autor:
Nelson B. Freimer, Anna J. Jasinska, Wesley C. Warren, Vasily Ramensky, Richard K. Wilson, Matthew J. Jorgensen, Giovanni Coppola, Ivette Zelaya, Hannes Svardal, Sandeep Deverasetty, J. Mark Cline, Jay R. Kaplan, Anastasia Zharikova
Genome sequencing studies of nonhuman primate (NHP) pedigree and population samples are discovering variants on a large and rapidly growing scale. These studies are increasing the utility of several NHP species as model systems for human disease. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc976373ca5f4a640b153ffc2a751f9
Autor:
Maggie P.Y. Lam, Ding Wang, Howard Choi, Haomin Li, John R. Yates, Peipei Ping, Dominic C. M. Ng, Edward Lau, Ivette Zelaya, David Meyer, Caiyun Fang, Nobel C. Zong
Publikováno v:
PROTEOMICS - Clinical Applications. 8:590-594
Purpose Altered proteasome functions are associated with multiple cardiomyopathies. While the proteasome targets polyubiquitinated proteins for destruction, it itself is modifiable by ubiquitination. We aim to identify the exact ubiquitination sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24301bdf00662ff6b61bc1db5177ce75
https://doi.org/10.1002/prca.201400029
https://doi.org/10.1002/prca.201400029
Autor:
Harley I. Kornblum, Riki Kawaguchi, Ivette Zelaya, Giovanni Coppola, Dan R. Laks, Thomas J. Crisman, Yining Zhao, Fuying Gao
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0164649 (2016)
PloS one, vol 11, iss 11
PLoS ONE
PloS one, vol 11, iss 11
PLoS ONE
We present here a novel genetic algorithm-based random forest (GARF) modeling technique that enables a reduction in the complexity of large gene disease signatures to highly accurate, greatly simplified gene panels. When applied to 803 glioblastoma m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81410de3ea480f5c0f4a12fd042dbebb
http://europepmc.org/articles/PMC5113897?pdf=render
http://europepmc.org/articles/PMC5113897?pdf=render
Autor:
Christine Peterson, Susan Service, Anna Jasinska, Fuying Gao, Ivette Zelaya, Terri Teshiba, Carrie Bearden, Victor Reus, Gabriel Macaya, Carlos López-Jaramillo, Marina Bogomolov, Yoav Benjamini, Eleazar Eskin, Giovanni Coppola, Nelson Freimer, Chiara Sabatti
The observation that variants regulating gene expression (expression quantitative trait loci, eQTL) are at a high frequency among SNPs associated with complex traits has made the genome-wide characterization of gene expression an important tool in ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f729ec6a44bb413aa43fada182c0b8f0
https://doi.org/10.1101/031427
https://doi.org/10.1101/031427
Autor:
Maggie P.Y. Lam, Jeong Ho Choi, Haomin Li, Huilong Duan, Nobel C. Zong, Peipei Ping, Ivette Zelaya, Ning Deng, Xiangbo Liang, Allen K. Kim
The innovations in mass spectrometry-based investigations in proteome biology enable systematic characterization of molecular details in pathophysiological phenotypes. However, the process of delineating large-scale raw proteomic datasets into a biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae1efa0666118cca1718340b1cf542c
https://europepmc.org/articles/PMC3737079/
https://europepmc.org/articles/PMC3737079/