Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ivett C. Piña"'
Autor:
Catherine M. Mills, Jonathan Turner, Ivett C. Piña, Kathleen A. Garrabrant, Dirk Geerts, André S. Bachmann, Yuri K. Peterson, Patrick M. Woster
Publikováno v:
European Journal of Medicinal Chemistry, 244:114818. Elsevier Masson SAS
Mills, C M, Turner, J, Piña, I C, Garrabrant, K A, Geerts, D, Bachmann, A S, Peterson, Y K & Woster, P M 2022, ' Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma ', European Journal of Medicinal Chemistry, vol. 244, 114818 . https://doi.org/10.1016/j.ejmech.2022.114818
Mills, C M, Turner, J, Piña, I C, Garrabrant, K A, Geerts, D, Bachmann, A S, Peterson, Y K & Woster, P M 2022, ' Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma ', European Journal of Medicinal Chemistry, vol. 244, 114818 . https://doi.org/10.1016/j.ejmech.2022.114818
The epigenetic regulator lysine specific demethylase 1 (LSD1), a MYCN cofactor, cooperatively silences MYCN suppressor genes. Furthermore, LSD1 has been correlated with adverse effects in neuroblastic tumors by propagating an undifferentiated, malign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6976025fd1feb3d3b098d8d697b480d
https://research.vumc.nl/en/publications/ebe1ebb1-a907-4adb-868e-f0f0d3a2cfba
https://research.vumc.nl/en/publications/ebe1ebb1-a907-4adb-868e-f0f0d3a2cfba
Autor:
Kashif Bashir, Phillip Crews, Ivett C. Piña, Shannon L. Kurz, Alyssa D. Thompson, Miriam Weinberg, Erin P. McCauley
Publikováno v:
The Journal of Antibiotics
Marine-derived bacteria are a prolific source of a wide range of structurally diverse natural products. This review, dedicated to Professor William Fenical, begins by showcasing many seminal discoveries made at the University of California San Diego