Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Iveta Vojtěchová"'
Publikováno v:
SAGE Open, Vol 14 (2024)
SuperAging deserves special attention from researchers in the field of the psychology of aging, because it denotes the preservation of multiple cognitive abilities in very old age. Currently, very little is known about lifestyle factors that could be
Externí odkaz:
https://doaj.org/article/003d16711a2342b18c0fdd5c6e125542
Autor:
Tomáš Macháček, Roman Leontovyč, Barbora Šmídová, Martin Majer, Oldřich Vondráček, Iveta Vojtěchová, Tomáš Petrásek, Petr Horák
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010302 (2022)
Helminth neuroinfections represent serious medical conditions, but the diversity of the host-parasite interplay within the nervous tissue often remains poorly understood, partially due to the lack of laboratory models. Here, we investigated the neuro
Externí odkaz:
https://doaj.org/article/47c135e664624f9c871112b938791765
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010929 (2022)
The amyloid cascade hypothesis, focusing on pathological proteins aggregation, has so far failed to uncover the root cause of Alzheimer's disease (AD), or to provide an effective therapy. This traditional paradigm essentially explains a mechanism inv
Externí odkaz:
https://doaj.org/article/86c1eabef5bb4e2ba0c3030e2228daa6
Autor:
Tomas Petrasek, Iveta Vojtechova, Ondrej Klovrza, Klara Tuckova, Cestmir Vejmola, Jakub Rak, Anna Sulakova, Daniel Kaping, Nadine Bernhardt, Petrus J. de Vries, Jakub Otahal, Robert Waltereit
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background Tuberous sclerosis complex (TSC), a multi-system genetic disorder often associated with autism spectrum disorder (ASD), is caused by mutations of TSC1 or TSC2, which lead to constitutive overactivation of mammalian target of rapam
Externí odkaz:
https://doaj.org/article/104950206a9247428bf829602f54418e
Autor:
Radomir Juza, Kristyna Stefkova, Wim Dehaen, Alena Randakova, Tomas Petrasek, Iveta Vojtechova, Tereza Kobrlova, Lenka Pulkrabkova, Lubica Muckova, Marko Mecava, Lukas Prchal, Eva Mezeiova, Kamil Musilek, Ondrej Soukup, Jan Korabecny
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1262 (2021)
In this pilot study, a series of new 3,4-dihydroquinolin-2(1H)-one derivatives as potential dopamine receptor D2 (D2R) modulators were synthesized and evaluated in vitro. The preliminary structure–activity relationship disclosed that compound 5e ex
Externí odkaz:
https://doaj.org/article/abb4ede6d98c4d9595af28bb1287f2f1
Autor:
Martina Janikova, Karolina Mainerova, Iveta Vojtechova, Tomas Petrasek, Jan Svoboda, Ales Stuchlik
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 1007 (2021)
Chronic sensitization to serotonin 1A and 7 receptors agonist 8-OH-DPAT induces compulsive checking and perseverative behavior. As such, it has been used to model obsessive-compulsive disorder (OCD)-like behavior in mice and rats. In this study, we t
Externí odkaz:
https://doaj.org/article/9343b94ace68434a8cfc318b1be5711d
Autor:
Iveta Vojtechova, Kristyna Maleninska, Viera Kutna, Ondrej Klovrza, Klara Tuckova, Tomas Petrasek, Ales Stuchlik
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3274 (2021)
Maternal immune activation (MIA) during pregnancy represents an important environmental factor in the etiology of schizophrenia and autism spectrum disorders (ASD). Our goal was to investigate the impacts of MIA on the brain and behavior of adolescen
Externí odkaz:
https://doaj.org/article/34d9987bfc5c47338acfd8794e216b3a
Autor:
Tomas Petrasek, Iveta Vojtechova, Veronika Lobellova, Anna Popelikova, Martina Janikova, Hana Brozka, Pavel Houdek, Martin Sladek, Alena Sumova, Zdenka Kristofikova, Karel Vales, Ales Stuchlík
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
The McGill-R-Thy1-APP transgenic rat is an animal model of the familial form of Alzheimer's disease (AD). This model mirrors several neuropathological hallmarks of the disease, including the accumulation of beta-amyloid and the formation of amyloid p
Externí odkaz:
https://doaj.org/article/ea1a2d0726404d48b8f46734a99774d3