Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Iveta Slapetova"'
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
James Wang, Lois Browne, Iveta Slapetova, Fei Shang, Kirsty Lee, Jodi Lynch, Julia Beretov, Renee Whan, Peter H. Graham, Ewan K. A. Millar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Triple negative breast cancer (TNBC) comprises 10–15% of all breast cancers and has a poor prognosis with a high risk of recurrence within 5 years. PD-L1 is an important biomarker for patient selection for immunotherapy but its cellular ex
Externí odkaz:
https://doaj.org/article/34c61617586b40f799dbf32a01b62a1c
Autor:
Sharon L. Wong, Nikhil T. Awatade, Miro A. Astore, Katelin M. Allan, Michael J. Carnell, Iveta Slapetova, Po-chia Chen, Alexander Capraro, Laura K. Fawcett, Renee M. Whan, Renate Griffith, Chee Y. Ooi, Serdar Kuyucak, Adam Jaffe, Shafagh A. Waters
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103710- (2022)
Summary: Characterization of I37R, a mutation located in the lasso motif of the CFTR chloride channel, was conducted by theratyping several CFTR modulators from both potentiator and corrector classes. Intestinal current measurements in rectal biopsie
Externí odkaz:
https://doaj.org/article/9a4dc92c469442f8afda25d75b18cedf
Autor:
Ewan Millar, Lois Browne, Iveta Slapetova, Fei Shang, Yuqi Ren, Rachel Bradshaw, Heather Ann Brauer, Sandra O’Toole, Julia Beretov, Renee Whan, Peter H. Graham
Publikováno v:
Cancers, Vol 12, Iss 9, p 2365 (2020)
Aim: To determine the prognostic significance of the immunophenotype of tumour-infiltrating lymphocytes (TILs) within a cohort of breast cancer patients with long-term follow-up. Methods: Multiplexed immunofluorescence and automated image analysis we
Externí odkaz:
https://doaj.org/article/15e41f9b6a7b4a7082ae111ea1278207
Publikováno v:
Cancer Research. 83:PD9-01
Triple negative breast cancer (TNBC) is the most aggressive breast cancer subtype with poor prognosis and limited treatment options. One of the mechanisms contributing to this is the ability of TNBC tumors to evade anti-tumour response, limiting the
Autor:
Elvis Pandzic, Nihan Turgutoglu, Iveta Slapetova, Renee Whan, Sharon L. Wong, Ling Zhong, Shafagh A. Waters, Adam Jaffe, Nikhil T. Awatade, Laura K. Fawcett, Alexander Capraro
Publikováno v:
Journal of Cystic Fibrosis. 20:364-371
Background Patient-derived airway cells differentiated at Air Liquid Interface (ALI) are valuable models for Cystic fibrosis (CF) precision therapy. Different culture expansion methods have been established to extend expansion capacity of airway basa
Autor:
Sharon L. Wong, Nikhil T. Awatade, Miro A. Astore, Katelin M. Allan, Michael J. Carnell, Iveta Slapetova, Po-chia Chen, Jeffry Setiadi, Elvis Pandzic, Laura K. Fawcett, John R. Widger, Renee M. Whan, Renate Griffith, Chee Y. Ooi, Serdar Kuyucak, Adam Jaffe, Shafagh A. Waters
Publikováno v:
American journal of respiratory cell and molecular biology. 67(1)
A significant challenge to making targeted cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies accessible to all individuals with cystic fibrosis (CF) are many mutations in the
Autor:
Sharon L. Wong, Nikhil T. Awatade, Miro A. Astore, Katelin M. Allan, Michael J. Carnell, Iveta Slapetova, Po-chia Chen, Alexander Capraro, Laura K. Fawcett, Renee M. Whan, Renate Griffith, Chee Y. Ooi, Serdar Kuyucak, Adam Jaffe, Shafagh A. Waters
Characterisation of I37R – a novel mutation in the lasso motif of ABC-transporter CFTR, a chloride channel – was conducted by theratyping using CFTR potentiators which increase channel gating activity and correctors which repair protein trafficki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cd7dc6f119d97803623f8fc0f71a943
https://doi.org/10.1101/2021.12.12.472297
https://doi.org/10.1101/2021.12.12.472297
Autor:
Renee Whan, James Wang, Ewan K.A. Millar, Kirsty Lee, Julia Beretov, Fei Shang, Iveta Slapetova, Jodi Lynch, Peter Graham, Lois Browne
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Triple negative breast cancer (TNBC) comprises 10–15% of all breast cancers and has a poor prognosis with a high risk of recurrence within 5 years. PD-L1 is an important biomarker for patient selection for immunotherapy but its cellular expression
Autor:
Katelin M. Allan, Jeffry Setiadi, Serdar Kuyucak, Laura K. Fawcett, John R. Widger, Renee Whan, Sharon L. Wong, Po-chia Chen, Michael Carnell, Adam Jaffe, Iveta Slapetova, Chee Y. Ooi, Shafagh A. Waters, Elvis Pandzic, Renate Griffith, Nikhil T. Awatade, Miro A. Astore
A significant challenge to making targeted CFTR modulator therapies accessible to all individuals with cystic fibrosis (CF) are many mutations in the CFTR gene that can cause CF, most of which remain uncharacterized. Here, we characterized the struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae71c9509600baaccdbd97ba3ff84db
https://doi.org/10.1101/2021.08.11.456003
https://doi.org/10.1101/2021.08.11.456003