Výsledky vyhledávání - "Iveta Mrízová"

Akademický článek

The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN™) Mice and Pure Enzymes

Autor: Marie Stiborová, Věra Černá, Michaela Moserová, Iveta Mrízová, Volker M. Arlt, Eva Frei

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 284-306 (2014)

Ellipticine is a DNA-damaging agent acting as a prodrug whose pharmacological efficiencies and genotoxic side effects are dictated by activation with cytochrome P450 (CYP). Over the last decade we have gained extensive experience in using pure enzyme

Externí odkaz: https://doaj.org/article/f8bf7614581f4129be4ea6f9685a8253

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Heterologous expression of human cytochrome P450 2S1 in

Autor: Iveta, Mrízová, Michaela, Moserová, Jan, Milichovský, Miroslav, Šulc, René, Kizek, Kateřina, Kubáčková, Volker M, Arlt, Marie, Stiborová

Publikováno v: Monatshefte Fur Chemie

Cytochrome P450 (CYP) 2S1 is “orphan” CYP that is overexpressed in several epithelial tissues and many human tumors. The pure enzyme is required for better understanding of its biological functions. Therefore, human CYP2S1 was considered to be pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::129b4fcd01f6a9c0c4a6ff94b4b42bc0
https://pubmed.ncbi.nlm.nih.gov/27110039

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Induced expression of microsomal cytochrome

Autor: Marie, Stiborová, Michaela, Moserová, Iveta, Mrízová, Helena, Dračínská, Václav, Martínek, Radek, Indra, Eva, Frei, Vojtěch, Adam, René, Kizek, Heinz H, Schmeiser, Kateřina, Kubáčková, Volker M, Arlt

Publikováno v: Monatshefte Fur Chemie

The microsomal protein cytochrome b 5, which is located in the membrane of the endoplasmic reticulum, has been shown to modulate many reactions catalyzed by cytochrome P450 (CYP) enzymes. We investigated the influence of exposure to the anticancer dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1951ebbd9af6a8b2a26cc4c870f6a07d
https://pubmed.ncbi.nlm.nih.gov/27110040

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Erratum to: Induced expression of microsomal cytochrome b 5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)

Autor: Marie Stiborová, Michaela Moserová, Iveta Mrízová, Helena Dračínská, Václav Martínek, Radek Indra, Eva Frei, Vojtěch Adam, René Kizek, Heinz H. Schmeiser, Kateřina Kubáčková, Volker M. Arlt

Publikováno v: Monatshefte für Chemie - Chemical Monthly. 148:1897-1897

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2df21e7864b6dc22229906a88988e9e
https://doi.org/10.1007/s00706-017-2011-z

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