Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Iveta Bernatova"'
Autor:
Sona Cacanyiova, Martina Cebova, Fedor Simko, Tomas Baka, Iveta Bernatova, Michal Kluknavsky, Stefan Zorad, Katarina Krskova, Ezgi Shaman, Anna Zemancikova, Andrej Barta, Basak G. Aydemir, Andrea Berenyiova
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-23 (2023)
Abstract Background Angiotensin converting enzyme 2 (ACE2) plays a crucial role in the infection cycle of SARS-CoV-2 responsible for formation of COVID-19 pandemic. In the cardiovascular system, the virus enters the cells by binding to the transmembr
Externí odkaz:
https://doaj.org/article/5aaaae2bd527423c9187dda7bfa601ac
Autor:
Michal Kluknavsky, Peter Balis, Silvia Liskova, Andrea Micurova, Martin Skratek, Jan Manka, Iveta Bernatova
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 947 (2024)
This study investigated the effects of chronic crowding-induced social stress and dimethyl fumarate (DMF) on borderline hypertensive rats, focusing on the transcription nuclear factor (erythroid-derived 2)-like 2 (NRF2) gene Nfe2l2, on the expression
Externí odkaz:
https://doaj.org/article/0bab3dff7ca64b43a57c44fb1b22e867
Autor:
Michal Kluknavsky, Andrea Micurova, Martin Skratek, Peter Balis, Monika Okuliarova, Jan Manka, Iveta Bernatova
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1475 (2023)
This study investigated genotype- and tissue-related differences in the biodistribution of superparamagnetic magnetite (Fe3O4) nanoparticles (IONs) into the heart and liver of normotensive Wistar Kyoto (WKY) and spontaneously hypertensive (SHR) rats
Externí odkaz:
https://doaj.org/article/e7b9136fd0f3490ebae121f0ccf47662
Autor:
Tomas Jasenovec, Dominika Radosinska, Marta Kollarova, Peter Balis, Stefan Zorad, Norbert Vrbjar, Iveta Bernatova, Sona Cacanyiova, Lubomira Tothova, Jana Radosinska
Publikováno v:
Life, Vol 12, Iss 12, p 2045 (2022)
Oxidative stress and multiple erythrocyte abnormalities have been observed in hypertension. We focused on the effects of angiotensin-converting enzyme 2 (ACE2) inhibition by MLN-4760 inhibitor on angiotensin peptides, oxidative stress parameters, and
Externí odkaz:
https://doaj.org/article/e7c85c1c2b8744cab68ef8bd00ad0d29
Autor:
Michal Kluknavsky, Andrea Micurova, Martina Cebova, Ezgi Şaman, Sona Cacanyiova, Iveta Bernatova
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2385 (2022)
Reduced angiotensin 1–7 bioavailability due to inhibition of angiotensin-converting enzyme 2 (ACE2) may contribute to increased mortality in hypertensive individuals during COVID-19. However, effects of ACE2 inhibitor MLN-4760 in brain functions re
Externí odkaz:
https://doaj.org/article/58faea74ffa74fa098f819ce774bc573
Autor:
Lucia Laubertova, Monika Dvorakova, Peter Balis, Angelika Puzserova, Ingrid Zitnanova, Iveta Bernatova
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 751 (2022)
Several studies have reported that the administration of various nanoparticles in vivo can cause oxidative stress. The combination of ultrasmall superparamagnetic iron oxide nanoparticles (USPIONs) and acute stress was selected because, during intrav
Externí odkaz:
https://doaj.org/article/d44df2bd322f40a88ad06606164665d5
Autor:
Andrea Micurova, Michal Kluknavsky, Silvia Liskova, Peter Balis, Martin Skratek, Ludmila Okruhlicova, Jan Manka, Iveta Bernatova
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1855 (2021)
We investigate the distribution and biological effects of polyethylene glycol (PEG)-coated magnetite (Fe3O4@PEG) nanoparticles (~30 nm core size, ~51 nm hydrodynamic size, 2 mg Fe/kg/day, intravenously, for two days) in the aorta and liver of Wistar
Externí odkaz:
https://doaj.org/article/8c36987efbeb435dbd8f6b79bc7bab6c
Autor:
Tomas Jasenovec, Dominika Radosinska, Marta Kollarova, Peter Balis, Ezgi Dayar, Iveta Bernatova, Stefan Zorad, Norbert Vrbjar, Sona Cacanyova, Jana Radosinska
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1902 (2021)
Various pathologies (COVID-19 including) are associated with abnormalities in erythrocyte properties. Hypertension represents an unfavorable condition for erythrocyte quality and is the most prevalent risk factor in COVID-19 patients. ACE2 downregula
Externí odkaz:
https://doaj.org/article/a11f2b991e024ba18ed5310c7a757086
Vascular Effects of Low-Dose ACE2 Inhibitor MLN-4760—Benefit or Detriment in Essential Hypertension?
Autor:
Andrea Berenyiova, Iveta Bernatova, Anna Zemancikova, Magdalena Drobna, Martina Cebova, Samuel Golas, Peter Balis, Silvia Liskova, Zuzana Valaskova, Katarina Krskova, Stefan Zorad, Ezgi Dayar, Sona Cacanyiova
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 38 (2021)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects host cells through angiotensin-converting enzyme 2 (ACE2). Concurrently, the product of ACE2 action, angiotensin 1–7 (Ang 1–7), binds to Mas receptors within the cardiovascular
Externí odkaz:
https://doaj.org/article/93fca31d376740868ae5a0cf68259e05
Autor:
Jana Radosinska, Tomas Jasenovec, Dominika Radosinska, Peter Balis, Angelika Puzserova, Martin Skratek, Jan Manka, Iveta Bernatova
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 377 (2021)
We determined erythrocyte physiological and biochemical properties after the single and repeated administration of ultra-small superparamagnetic iron-oxide nanoparticles (USPIONs) in normotensive Wistar–Kyoto (WKY) and spontaneously hypertensive (S
Externí odkaz:
https://doaj.org/article/d0b90e5e8c1a4fb194bebd639f628640