Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Iver A Langmoen"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114739 (2014)
There is a great potential for the development of new cell replacement strategies based on adult human neural stem-like cells. However, little is known about the hierarchy of cells and the unique molecular properties of stem- and progenitor cells of
Externí odkaz:
https://doaj.org/article/f153c6e39a624e258f9272084f6cc435
Autor:
Wayne Murrell, Emily Palmero, John Bianco, Biljana Stangeland, Mrinal Joel, Linda Paulson, Bernd Thiede, Zanina Grieg, Ingunn Ramsnes, Håvard K Skjellegrind, Ståle Nygård, Petter Brandal, Cecilie Sandberg, Einar Vik-Mo, Sheryl Palmero, Iver A Langmoen
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71334 (2013)
The discovery of stem cells in the adult human brain has revealed new possible scenarios for treatment of the sick or injured brain. Both clinical use of and preclinical research on human adult neural stem cells have, however, been seriously hampered
Externí odkaz:
https://doaj.org/article/e447bd1252084b438336d0ade57ddc79
Autor:
Artem Fayzullin, Cecilie J. Sandberg, Matthew Spreadbury, Birthe Mikkelsen Saberniak, Zanina Grieg, Erlend Skaga, Iver A. Langmoen, Einar O. Vik-Mo
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 122-133 (2019)
BACKGROUND: Tumor cell invasion is a hallmark of glioblastoma (GBM) and a major contributing factor for treatment failure, tumor recurrence, and the poor prognosis of GBM. Despite this, our understanding of the molecular machinery that drives invasio
Externí odkaz:
https://doaj.org/article/0af2052a07984b2e92e35d74c67676d5
Autor:
Awais A. Mughal, Lili Zhang, Artem Fayzullin, Andres Server, Yuping Li, Yingxi Wu, Rainer Glass, Torstein Meling, Iver A. Langmoen, Trygve B. Leergaard, Einar O. Vik-Mo
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 7, Pp 643-656 (2018)
BACKGROUND: Widespread infiltration of tumor cells into surrounding brain parenchyma is a hallmark of malignant gliomas, but little data exist on the overall invasion pattern of tumor cells throughout the brain. METHODS: We have studied the invasive
Externí odkaz:
https://doaj.org/article/e7d8f0c670ea40aa9340e000e558579b
Autor:
Erlend Skaga, Evgeny Kulesskiy, Swapnil Potdar, Ioannis Panagopoulos, Francesca Micci, Iver A. Langmoen, Cecilie J. Sandberg, Einar O. Vik-Mo
Publikováno v:
Translational Oncology. 26:101535
Serum-free culturing of patient-derived glioblastoma biopsies enrich for glioblastoma stem cells (GSCs) and is recognized as a disease-relevant model system in glioblastoma (GBM). We hypothesized that the temozolomide (TMZ) drug sensitivity of patien
Autor:
Iver A. Langmoen, Einar O. Vik-Mo, Luna Djirackor, Luis P. Kuschel, Pitt Niehusmann, Henning Leske, Jens Pahnke, Bernt J. Due-Tønnessen, Philipp Euskirchen, David Capper, Skarphedinn Halldorsson, Cecilie Sandberg
Publikováno v:
Neuro-oncology Advances
Background Brain tumor surgery must balance the benefit of maximal resection against the risk of inflicting severe damage. The impact of increased resection is diagnosis-specific. However, the precise diagnosis is typically uncertain at surgery due t
Autor:
Zanina Grieg, Cecilie Sandberg, Iver A. Langmoen, Erlend Skaga, Ida Ø. Skaga, Einar O. Vik-Mo
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Constructed from a theoretical framework, the coordinated undermining of survival paths in glioblastoma (GBM) is a combination of nine drugs approved for non-oncological indications (CUSP9; aprepitant, auranofin, captopril, celecoxib, disulfi
Autor:
Iver A. Langmoen, Erlend Skaga, Matthew Spreadbury, Cecilie Sandberg, Artem Fayzullin, Einar O. Vik-Mo, Zanina Grieg, Birthe Mikkelsen Saberniak
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 122-133 (2019)
BACKGROUND: Tumor cell invasion is a hallmark of glioblastoma (GBM) and a major contributing factor for treatment failure, tumor recurrence, and the poor prognosis of GBM. Despite this, our understanding of the molecular machinery that drives invasio
Autor:
Erlend Skaga, Marthe Andrea Skretteberg, Petter Brandal, Einar O. Vik-Mo, Eirik Helseth, Iver A. Langmoen, Tom Børge Johannesen
Publikováno v:
Neuro-oncology Advances
Background The survival rates in population-based series of glioblastoma (GBM) differ substantially from those reported in clinical trials. This discrepancy may be attributed to that patients recruited to trials tend to be younger with better perform
Autor:
Einar O. Vik-Mo, Erlend Skaga, Jo Waaler, Kaja Lund, Stefan Krauss, Iver A. Langmoen, Kirsten Strømme Kierulf-Vieira, Petter Brandal, Cecilie Sandberg, Ioannis Panagopoulos, Birthe Mikkelsen Saberniak
Publikováno v:
Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1630, p 1630 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1630, p 1630 (2020)
Evidence suggests that the growth and therapeutic resistance of glioblastoma (GBM) may be enabled by a population of glioma stem cells (GSCs) that are regulated by typical stem cell pathways, including the WNT/&beta
catenin signaling pathway. We
catenin signaling pathway. We