Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ivelisse, Cajigas"'
Autor:
Kelsey R. Swyter, Ferhat Ay, Hao Luo, Ivelisse Cajigas, Linden Collens, Abhijit Chakraborty, Monique Bastidas, Madison Lynam, Jhumku D. Kohtz
Publikováno v:
Development
The Evf2 long non-coding RNA directs Dlx5/6 ultraconserved enhancer(UCE)-intrachromosomal interactions, regulating genes across a 27 Mb region on chromosome 6 in mouse developing forebrain. Here, we show that Evf2 long-range gene repression occurs th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c8e34fd24a6bd0edd12de0a6e946fa
https://europepmc.org/articles/PMC7990859/
https://europepmc.org/articles/PMC7990859/
Autor:
Jhumku D. Kohtz, Kelsey R. Swyter, Ferhat Ay, Ivelisse Cajigas, Hao Luo, Madison Lynam, Linden Collens, Abhijit Chakraborty, Monique Bastidas
SummaryPrecise regulation of gene expression networks requires the selective targeting of DNA enhancers. The Evf2 long non-coding RNA regulates Dlx5/6 ultraconserved enhancer(UCE) interactions with long-range target genes, controlling gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6475eda624b96857b9136e25e4b8b8a3
https://doi.org/10.1101/2020.09.22.307215
https://doi.org/10.1101/2020.09.22.307215
Autor:
Donna Garvey Brickner, Ivelisse Cajigas, Yvonne Fondufe-Mittendorf, Sara Ahmed, Pei-Chih Lee, Jonathan Widom, Jason H Brickner
Publikováno v:
PLoS Biology, Vol 5, Iss 4, p e81 (2007)
Many genes are recruited to the nuclear periphery upon transcriptional activation. The mechanism and functional significance of this recruitment is unclear. We find that recruitment of the yeast INO1 and GAL1 genes to the nuclear periphery is rapid a
Externí odkaz:
https://doaj.org/article/c35b59de67784851b17ad0edb634174d
Autor:
Chunming Bi, Jhumku D. Kohtz, Diana S. Himmelstein, Grant Van Der Voort, Ivelisse Cajigas, Brian S. Clark
Publikováno v:
Developmental Biology. 424:221-235
Sonic hedgehog (SHH) is a master developmental regulator. In 1995, the SHH crystal structure predicted that SHH-E176 (human)/E177 (mouse) regulates signaling through a Zn2+-dependent mechanism. While Zn2+ is known to be required for SHH protein stabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532933c70a786553a9896d6e480c9b4e
https://doi.org/10.1016/j.ydbio.2017.02.006
https://doi.org/10.1016/j.ydbio.2017.02.006
Autor:
Sara J. Kohtz, Abhijit Chakraborty, Ivelisse Cajigas, Monique Bastidas, Kelsey S. Swyter, Jhumku D. Kohtz, Ferhat Ay
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4c0a90d1e32aa5256990e675efad59
https://doi.org/10.1096/fasebj.2018.32.1_supplement.525.19
https://doi.org/10.1096/fasebj.2018.32.1_supplement.525.19
Previously expressed inducible genes can remain poised for faster reactivation for multiple cell divisions, a conserved phenomenon called epigenetic transcriptional memory. The GAL genes in Saccharomyces cerevisiae show faster reactivation for up to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e641354519c2af99b886fc08f759332b
https://europepmc.org/articles/PMC5560796/
https://europepmc.org/articles/PMC5560796/
Autor:
Ivelisse Cajigas, Amy Leung, Zhongming Zhao, Jason H. Brickner, Elena Ezhkova, Fuqiang Geng, William P. Tansey, Peilin Jia
Publikováno v:
Molecular Biology of the Cell
Evidence is presented that the linked histone modifications H2B ubiquitylation and H3 methylation play an important role in preventing the ectopic association of silencing proteins with telomere-distant euchromatic genes important for the cellular re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043db635049a4d2beb7cef3f44268b26
https://doi.org/10.1091/mbc.e11-05-0426
https://doi.org/10.1091/mbc.e11-05-0426
Autor:
Michael J.W. VanGompel, Elizabeth R. Morris, Sooky Koh, Sean Chen, Sara J. Kohtz, Jhumku D. Kohtz, Ivelisse Cajigas, Maximilliano Nigro, Marco Martina, Kelsey R. Swyter, David E. Leib, Hao Luo, Abhijit Chakraborty, Monique Bastidas, Ferhat Ay
Publikováno v:
Molecular Cell. 71:956-972.e9
Gene regulation requires selective targeting of DNA regulatory enhancers over megabase (Mb) distances. Here, we show that Evf2, a cloud-forming Dlx5/6 ultraconserved enhancer (UCE) lncRNA simultaneously localizes to activated (Umad1, 1.6Mb distant) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7425d7359b971a68a69ca2180defb5a
https://doi.org/10.1016/j.molcel.2018.07.024
https://doi.org/10.1016/j.molcel.2018.07.024
Autor:
Tom Volpe, Michele McDonough, Jason H. Brickner, Donna G. Brickner, Ivelisse Cajigas, William H. Light, Sara Ahmed, Alexander B. Froyshteter
Publikováno v:
Nature cell biology
Many genes in Saccharomyces cerevisiae are recruited to the nuclear periphery after transcriptional activation. We have identified two gene recruitment sequences (GRS I and II) from the promoter of the INO1 gene that target the gene to the nuclear pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91978d7734d81b97162dfc54eb409d0b
https://doi.org/10.1038/ncb2011
https://doi.org/10.1038/ncb2011
Autor:
Ivelisse, Cajigas, David E, Leib, Jesse, Cochrane, Hao, Luo, Kelsey R, Swyter, Sean, Chen, Brian S, Clark, James, Thompson, John R, Yates, Robert E, Kingston, Jhumku D, Kohtz
Publikováno v:
Development (Cambridge, England). 142(15)
Transcription-regulating long non-coding RNAs (lncRNAs) have the potential to control the site-specific expression of thousands of target genes. Previously, we showed that Evf2, the first described ultraconserved lncRNA, increases the association of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::632bd0b92258fa8a44b306ee38abb100
https://pubmed.ncbi.nlm.nih.gov/26138476
https://pubmed.ncbi.nlm.nih.gov/26138476