Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Ivano Eberini"'
Autor:
Yao Wei, Luca Palazzolo, Omar Ben Mariem, Davide Bianchi, Tommaso Laurenzi, Uliano Guerrini, Ivano Eberini
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3090-3103 (2024)
Cytochrome P450 (CYP450) enzymes comprise a highly diverse superfamily of heme-thiolate proteins that responsible for catalyzing over 90 % of enzymatic reactions associated with xenobiotic metabolism in humans. Accurately predicting whether chemicals
Externí odkaz:
https://doaj.org/article/42f7b7f4a26f4d969ea93f284bf78cab
Autor:
Simona Saporiti, Davide Bianchi, Omar Ben Mariem, Mara Rossi, Uliano Guerrini, Ivano Eberini, Fabio Centola
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionN-glycosylation is a post-translational modification that is highly important for the development of monoclonal antibodies (mAbs), as it regulates their biological activity, particularly in terms of immune effector functions. While typica
Externí odkaz:
https://doaj.org/article/f8f10b3d86614d7f855588dde31c64e0
Autor:
Sara Della Torre, Giulia Dell’Omo, Jessica Dellavedova, Luca Palazzolo, Eugenio Scanziani, Ivano Eberini, Andrea Pinto, Nico Mitro, Paola Conti, Alessandro Villa, Paolo Ciana
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107296- (2024)
The activity of sirtuin 1 (SIRT1, a member of the NAD+-dependent deacetylases family) decreases during aging as NAD+ levels naturally decline, thus increasing the risk of several age-associated diseases. Several sirtuin-activating compounds (STACs) h
Externí odkaz:
https://doaj.org/article/da9be06b663c449cb14ab3ce88afd37c
Autor:
Antonella Lettieri, Roberto Oleari, Marleen Hester van den Munkhof, Eljo Yvette van Battum, Marieke Geerte Verhagen, Carlotta Tacconi, Marco Spreafico, Alyssa Julia Jennifer Paganoni, Roberta Azzarelli, Valentina Andre’, Federica Amoruso, Luca Palazzolo, Ivano Eberini, Leo Dunkel, Sasha Rose Howard, Alessandro Fantin, Ronald Jeroen Pasterkamp, Anna Cariboni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction. However, the molecular and cellular mechanisms underlying median eminence developm
Externí odkaz:
https://doaj.org/article/29e7636892604491a5617dd5dec8d237
Autor:
Omar Ben Mariem, Luca Palazzolo, Beatrice Torre, Yao Wei, Davide Bianchi, Uliano Guerrini, Tommaso Laurenzi, Simona Saporiti, Emma De Fabiani, Lorena Pochini, Cesare Indiveri, Ivano Eberini
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304512 (2024)
The Organic Cation Transporter Novel 1 (OCTN1), also known as SLC22A4, is widely expressed in various human tissues, and involved in numerous physiological and pathological processes remains. It facilitates the transport of organic cations, zwitterio
Externí odkaz:
https://doaj.org/article/142668bdd25f42b9ae9ac75c8fd01b1e
Autor:
Francesca Re, Sofia Giorgetti, Barbara Biondi, Stefano Scapin, Francesco Mantegazza, Valeria Cassina, Silvia Maria Sesana, Laura Rizzi, Ivano Eberini, Luca Palazzolo, Marten Beeg, Marco Gobbi, Marco Sardina, Massimo Masserini
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractAim The effect of liposomes bi-functionalized with phosphatidic acid and with a synthetic peptide derived from human apolipoprotein E has been evaluated on the aggregation features of different amyloidogenic proteins: human Amyloid β1–40 (
Externí odkaz:
https://doaj.org/article/f28ca372cf6d4d4ab6a34ae319ebc629
Autor:
Simona Saporiti, Tommaso Laurenzi, Uliano Guerrini, Crescenzo Coppa, Wolf Palinsky, Giulia Benigno, Luca Palazzolo, Omar Ben Mariem, Linda Montavoci, Mara Rossi, Fabio Centola, Ivano Eberini
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Classical and accelerated molecular dynamics simulations reveal how core fucosylation in the IgG1 Fc glycan and the light chain isotype modulate the conformational behavior of the hinge and Fab domains and dynamics of IgG1 antibodies.
Externí odkaz:
https://doaj.org/article/043e09b73eb1488ea9d072900710a023
Autor:
Lorena Pochini, Michele Galluccio, Lara Console, Mariafrancesca Scalise, Ivano Eberini, Cesare Indiveri
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 392 (2024)
Inflammation is a physiological condition characterized by a complex interplay between different cells handled by metabolites and specific inflammatory-related molecules. In some pathological situations, inflammation persists underlying and worsening
Externí odkaz:
https://doaj.org/article/e599cf5177134ca3acc91aecbac10af1
Autor:
Linda Montavoci, Omar Ben Mariem, Simona Saporiti, Tommaso Laurenzi, Luca Palazzolo, Alice Federica Ossoli, Uliano Guerrini, Laura Calabresi, Ivano Eberini
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3555 (2024)
Angiopoietin-like protein 3 (ANGPTL3) is a plasmatic protein that plays a crucial role in lipoprotein metabolism by inhibiting the lipoprotein lipase (LPL) and the endothelial lipase (EL) responsible for the hydrolysis of phospholipids on high-densit
Externí odkaz:
https://doaj.org/article/a1ec7db912be4742b4871e640cac834e
Autor:
Valentina Traini, Giuseppina Fabbiano, Domenica Ronchetti, Ilaria Silvestris, Vanessa Katia Favasuli, Silvia Erratico, Domenica Giannandrea, Tommaso Laurenzi, Luca Palazzolo, Yvan Torrente, Raffaella Chiaramonte, Ivano Eberini, Niccolò Bolli, Antonino Neri, Elisa Taiana
Publikováno v:
HemaSphere, Vol 7, p e229153d (2023)
Externí odkaz:
https://doaj.org/article/bce2a456c32642049b0b045e8698ffa9