Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ivanna V, Bihun"'
Autor:
Priscilla K. Brastianos, Hiroaki Wakimoto, Daniel P. Cahill, Scott L. Carter, Maria Martinez-Lage, Anita Giobbie-Hurder, Megha Subramanian, Jianfang Ning, Gregory R. Wojtkiewicz, Stephen P. Schmidt, Tristan Penson, Matthew Lastrapes, Ivanna V. Bihun, Alexandria L. Fink, Benjamin M. Kuter, Christopher A. Alvarez-Breckenridge, Franziska M. Ippen
Purpose:Previous studies have shown that the PI3K/Akt/mTOR pathway is activated in up to 70% of breast cancer brain metastases, but there are no approved agents for affected patients. GDC-0084 is a brain penetrant, dual PI3K/mTOR inhibitor that has s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4462a59ba850ac6cd3caddecb662fc76
https://doi.org/10.1158/1078-0432.c.6527592
https://doi.org/10.1158/1078-0432.c.6527592
Autor:
Priscilla K. Brastianos, Hiroaki Wakimoto, Daniel P. Cahill, Scott L. Carter, Maria Martinez-Lage, Anita Giobbie-Hurder, Megha Subramanian, Jianfang Ning, Gregory R. Wojtkiewicz, Stephen P. Schmidt, Tristan Penson, Matthew Lastrapes, Ivanna V. Bihun, Alexandria L. Fink, Benjamin M. Kuter, Christopher A. Alvarez-Breckenridge, Franziska M. Ippen
Western blot analysis of p-p44/42 MAPK (Erk1/2) (Thr202/Tyr204), p-MEK1/2 (Ser217/221), p-p90RSK (Ser380), p-MSK1 (Thr581) in JIMT-1 BR-3, MDA-MB-361, MDA-MB-231 BrM2 and BS-004 cell lines treated with GDC-0084 in increasing concentrations for a tota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc25e6af1c18a10c51316128945a202
https://doi.org/10.1158/1078-0432.22470510.v1
https://doi.org/10.1158/1078-0432.22470510.v1
Autor:
Priscilla K. Brastianos, Hiroaki Wakimoto, Daniel P. Cahill, Scott L. Carter, Maria Martinez-Lage, Anita Giobbie-Hurder, Megha Subramanian, Jianfang Ning, Gregory R. Wojtkiewicz, Stephen P. Schmidt, Tristan Penson, Matthew Lastrapes, Ivanna V. Bihun, Alexandria L. Fink, Benjamin M. Kuter, Christopher A. Alvarez-Breckenridge, Franziska M. Ippen
Photomicrographs illustrating p-MEK1/2 (Ser221) and p-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) expression in mouse brains harboring either JIMT-1 BR-3 or MDA-MB-231 BrM2 intracranial tumors, stratified by treatment with sham or GDC-0084.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe3b839cacdc04735a7be46993e31f4
https://doi.org/10.1158/1078-0432.22470504.v1
https://doi.org/10.1158/1078-0432.22470504.v1
Autor:
Priscilla K. Brastianos, Hiroaki Wakimoto, Daniel P. Cahill, Scott L. Carter, Maria Martinez-Lage, Anita Giobbie-Hurder, Megha Subramanian, Jianfang Ning, Gregory R. Wojtkiewicz, Stephen P. Schmidt, Tristan Penson, Matthew Lastrapes, Ivanna V. Bihun, Alexandria L. Fink, Benjamin M. Kuter, Christopher A. Alvarez-Breckenridge, Franziska M. Ippen
GDC-0084-induced changes in cell cycle in the PIK3CA-mutant cell line MDA-MB-361 and in the PIK3CA-wildtype cell line BS-004
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a4ca0d25b0649bebbb06ee5469fa58
https://doi.org/10.1158/1078-0432.22470507.v1
https://doi.org/10.1158/1078-0432.22470507.v1
Publikováno v:
Wound Repair and Regeneration. 25:234-247
The prevalence of cutaneous fibroproliferative disorders (CFPDs) is high and almost exclusively occurs in humans (keloids and hypertrophic scars) and horses (exuberant granulation tissue), making the horse a valuable translational model for studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6b86c01bb3f631c9acd072bd10d1bd4
https://doi.org/10.1111/wrr.12515
https://doi.org/10.1111/wrr.12515
Autor:
Sally R, Williams, Tareq A, Juratli, Brandyn A, Castro, Tyler T, Lazaro, Corey M, Gill, Naema, Nayyar, Matthew R, Strickland, Melanie, Babinski, Sarah E, Johnstone, Matthew P, Frosch, Ian M, Silverman, Heather A, Ely, Alexander B, Kaplan, Megan R, D'Andrea, Ivanna V, Bihun, Kaitlin, Hoang, Emily, Batchelor, Jason, Christiansen, Daniel P, Cahill, Frederick G, Barker, Priscilla K, Brastianos
Publikováno v:
J Neurol Surg B Skull Base
Objective Posterior fossa meningiomas are surgically challenging tumors that are associated with high morbidity and mortality. We sought to investigate the anatomical distribution of clinically actionable mutations in posterior fossa meningioma to fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d8de515148a824ef563ab984cf7f8a8
https://pubmed.ncbi.nlm.nih.gov/31750041
https://pubmed.ncbi.nlm.nih.gov/31750041
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 25(2)
The prevalence of cutaneous fibroproliferative disorders (CFPDs) is high and almost exclusively occurs in humans (keloids and hypertrophic scars) and horses (exuberant granulation tissue), making the horse a valuable translational model for studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ad7b0ae1b42917180ba1fab02df415b
https://pubmed.ncbi.nlm.nih.gov/28370679
https://pubmed.ncbi.nlm.nih.gov/28370679