Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ivanka I, Kostadinova"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 170:200-202
The effect of original peptide derivatives of galantamine on scopolamine-induced memory impairment in mice was assessed using the passive avoidance test over 12 days. It was found that some galantamine derivatives administered in a dose of 1/20LD50 i
Autor:
Ivanka I. Kostadinova, Vessela Vitcheva, Irini Doytchinova, Irena Philipova, Nikolai Danchev, Georgi Stavrakov, Rumiana Simeonova, Iva Valkova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daaad42f6d2be85af1c2eaf90a244c54
https://doi.org/10.7546/crabs.2021.06.13
https://doi.org/10.7546/crabs.2021.06.13
Autor:
Irena Philipova, Ivanka I. Kostadinova, Vessela Vitcheva, Rumiana Simeonova, Irini Doytchinova, Nikolai Danchev, Georgi Stavrakov, Iva Valkova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8131e7090539054fc826aad1f984b1e
https://doi.org/10.7546/crabs.2021.02.08
https://doi.org/10.7546/crabs.2021.02.08
Autor:
Boycho Landzhov, Nikolai Danchev, Lyubomir T. Vezenkov, Ivanka I. Kostadinova, Lyubomir Marinov
Publikováno v:
Amino acids. 53(8)
The aim of this study was to assess the effect of newly synthesized derivatives of 4-aminopyridine (4-AP) on cuprizone-induced model of brain demyelination in mice. 4-AP is already approved for the treatment of walking difficulties in patients with m
Autor:
Stela Dimitrova, H. Zlatanova, Ivanka I. Kostadinova, Mariana Katsarova, Ferit Sadakov, I. Kandilarov, Ludmil Lukanov, M. Georgieva-Kotetarova
Publikováno v:
Folia Medica, Vol 60, Iss 1, Pp 110-116 (2018)
Background: Chronic stress is one of the main factors which lead to depression – a psychiatric disorder affecting millions of people and predicted to be the second ranked cause of premature death in 2020. Depression is often associated with cogniti
Autor:
Atanas Bijev, Stanislava Vladimirova, Delian Delev, Ivanka I. Kostadinova, H. Zlatanova, Tanya Deneva, Ilia Kostadinov
Publikováno v:
International Journal of Pain Management. 1:1-11
The objective of our study was to evaluate the analgesic and anti-inflammatory activity, as well as possible organ toxicity of 2-3-3-methyl-pentanoic acid (compound 3d), a newly synthesized pyrrolic derivative, structurally similar to Celecoxib. Anti
Autor:
Tanya Deneva, Ivanka I. Kostadinova, Ilia Kostadinov, H. Zlatanova, Stanislava Vladimirova, Delian Delev
Publikováno v:
Medicina; Volume 55; Issue 4; Pages: 93
Medicina
Volume 55
Issue 4
Medicina, Vol 55, Iss 4, p 93 (2019)
Medicina
Volume 55
Issue 4
Medicina, Vol 55, Iss 4, p 93 (2019)
Background and objectives: The clinical use of non-steroidal anti-inflammatory drugs is limited due to high incidence of adverse drug reactions. The pyrrole heterocycle is included in the chemical structure of a number of drugs with various activitie
Autor:
Ivanka I. Kostadinova, Nikolai Danchev
Publikováno v:
Pharmacia 66(2): 67-74
Pharmacia, Vol 66, Iss 2, Pp 67-74 (2019)
Pharmacia, Vol 66, Iss 2, Pp 67-74 (2019)
In this review are described the preclinical and clinical pharmacological data as well as new therapeutic indications for the use of 4-aminopyridine. 4-aminopyridine is a potassium (K+) channel blocker that has a long history and various application
Autor:
Ivanka I. Kostadinova, Rositsa Mihaylova, D. Tsekova, Lyubomir T. Vezenkov, Nikolay G. Vassilev, Nikolai Danchev
Publikováno v:
Current Alzheimer research. 16(3)
Background: Although no effective treatment for the Alzheimer’s disease currently exist, some drugs acting as Acetylcholinesterase inhibitors, like galanthamine have positively affected such patients. β- and/or γ-secretase inhibitors are another