Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ivana Saska"'
Autor:
Nobuaki Ishihama, Seung-won Choi, Yoshiteru Noutoshi, Ivana Saska, Shuta Asai, Kaori Takizawa, Sheng Yang He, Hiroyuki Osada, Ken Shirasu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The plant defense hormone salicylic acid has structural similarity to oxicam-type non-steroidal antiinflammatories. Here the authors show oxicams, as well as endogenous salicylic acid, can alter cellular redox state and immune signaling without affec
Externí odkaz:
https://doaj.org/article/2287a9aab2064158bd321dcc81689e62
Autor:
Karen S. Harris, Norelle L. Daly, Ivana Saska, Edward K. Gilding, Brendon Conlan, Nicole L. van der Weerden, Quentin Kaas, Marilyn A. Anderson, David J. Craik, Aaron G. Poth, Thomas Durek
Publikováno v:
Nature Communications
Cyclotides are diverse plant backbone cyclized peptides that have attracted interest as pharmaceutical scaffolds, but fundamentals of their biosynthetic origin remain elusive. Backbone cyclization is a key enzyme-mediated step of cyclotide biosynthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0e9044394f1bf3034cda1db0c65939
http://europepmc.org/articles/PMC4703859
http://europepmc.org/articles/PMC4703859
Publikováno v:
Journal of Peptide Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedc6edc32c4e2075e6cc33bb77efcad
https://doi.org/10.1002/psc.1089
https://doi.org/10.1002/psc.1089
Autor:
Ivana Saska, David J. Craik
Publikováno v:
Trends in Biochemical Sciences. 33:363-368
In all organisms, proteases catalyse peptide-bond hydrolysis and mediate protein function for a multitude of cellular processes. Mechanistically, nothing prevents proteases from also catalysing peptide-bond ligation; however, this 'reverse' reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f405a460400d5722e4e0d30c61c7041d
https://doi.org/10.1016/j.tibs.2008.04.016
https://doi.org/10.1016/j.tibs.2008.04.016
Autor:
Noriyuki Hatsugai, Ivana Saska, Ikuko Hara-Nishimura, Marilyn A. Anderson, Amanda D. Gillon, David J. Craik, Ralf G. Dietzgen
Publikováno v:
Journal of Biological Chemistry. 282:29721-29728
Proteases can catalyze both peptide bond cleavage and formation, yet the hydrolysis reaction dominates in nature. This presents an interesting challenge for the biosynthesis of backbone cyclized (circular) proteins, which are encoded as part of precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f906a93e9cb6953634c611443806886
https://doi.org/10.1074/jbc.m705185200
https://doi.org/10.1074/jbc.m705185200
Publikováno v:
Journal of Bacteriology. 185:4011-4021
Bacteria produce a wide variety of both proteinaceous and nonproteinaceous molecules for defense, mediation of microbial competitions, and signaling purposes. Of the protein-based molecules, there are examples of large folded polypeptides that are tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733bc7b96923e2e5970eac0d445e2c54
https://doi.org/10.1128/jb.185.14.4011-4021.2003
https://doi.org/10.1128/jb.185.14.4011-4021.2003
Autor:
Ivana Saska, Joshua S. Mylne, Qiaoping Qin, David J. Craik, Emily J. McCallum, Jan Suda, Quentin Kaas
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 111 (2010)
BMC Genomics
BMC Genomics
Background Cyclotides are a family of circular peptides that exhibit a range of biological activities, including anti-bacterial, cytotoxic, anti-HIV activities, and are proposed to function in plant defence. Their high stability has motivated their d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4564c70967adec07abe2fb60475931
http://www.biomedcentral.com/1471-2164/11/111
http://www.biomedcentral.com/1471-2164/11/111
Autor:
Amanda D, Gillon, Ivana, Saska, Cameron V, Jennings, Rosemary F, Guarino, David J, Craik, Marilyn A, Anderson
Publikováno v:
The Plant journal : for cell and molecular biology. 53(3)
Plant cyclotides are a large family of naturally occurring circular proteins that are produced from linear precursors containing one, two or three cyclotide domains. The mechanism of excision of the cyclotide domains and ligation of the free N- and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa49e5e7c10037a90022bfe971f22dfa
https://pubmed.ncbi.nlm.nih.gov/18086282
https://pubmed.ncbi.nlm.nih.gov/18086282