Výsledky vyhledávání - "Ivana Pilchova"

The effect of temozolomide on apoptosis-related gene expression changes in glioblastoma cells

Autor: Eva VIDOMANOVA, Zuzana MAJERCIKOVA, Katarina DIBDIAKOVA, Ivana PILCHOVA, Peter RACAY, Jozef HATOK

Publikováno v: Bratislavske lekarske listy. 123(4)

Glioblastoma (GB) is the most common and biologically the most aggressive primary brain tumor of the central nervous system (CNS) in adults. Standard treatment for newly diagnosed GB consists of surgical resection, radiotherapy, and chemotherapy with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47b942933a6af7c266a972fb215613a
https://pubmed.ncbi.nlm.nih.gov/35294208

Zobrazit plný text záznamu

Assessment of bioavailability of Mg from Mg citrate and Mg oxide by measuring urinary excretion in Mg-saturated subjects

Autor: Tanja, Werner, Martin, Kolisek, Jürgen, Vormann, Ivana, Pilchova, Marian, Grendar, Eva, Struharnanska, Michal, Cibulka

Publikováno v: Magnesium research. 32(3)

Low magnesium (Mg) levels are linked to many diseases. Studies suggest that organic salts of Mg are more readily bioavailable than its oxide or inorganic salts used for supplements production. Unfortunately, the plethora of variables in the previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9fa54f07fc9d6a58b0532d853f8e0116
https://pubmed.ncbi.nlm.nih.gov/32162607

Zobrazit plný text záznamu

Both thapsigargin- and tunicamycin-induced endoplasmic reticulum stress increases expression of Hrd1 in IRE1-dependent fashion

Autor: Ivana Pilchova, Zuzana Tatarkova, Peter Racay, Katarina Dibdiakova, Simona Saksonova, Katarina Klacanova

Publikováno v: Neurological Research. 41:177-188

We have investigated the impact of endoplasmic reticulum (ER) stress, which is often implicated in neurodegenerative diseases, on the expression of Hrd1, an E3 ubiquitin ligase that plays a central role in the process of ER-associated degradation (ER

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00acbeb0e146f3b91c6bd972e602eb89
https://doi.org/10.1080/01616412.2018.1547856

Zobrazit plný text záznamu

Cobalt chloride affects the death of SH-SY5Y cells induced by inhibition of ubiquitin proteasome system. Role of heat shock protein 70 and caspase 3

Autor: Ivana Pilchova, Jozef Hatok, Simona Saksonova, Mária Brodňanová, Peter Racay, Katarina Klacanova, Katarina Dibdiakova

Publikováno v: General physiology and biophysics. 37:667-676

The aim our study was to investigate protective effect of cobalt chloride (CoCl2) in the model of proteasome stress of neuroblastoma SH-SY5Y cells induced by bortezomib, an inhibitor of 26S proteasome. We have focused our interests on Hsp70 and activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e32a38c8a7314793220f14e7c38036
https://doi.org/10.4149/gpb_2018022

Zobrazit plný text záznamu

Proteasome Stress Triggers Death of SH-SY5Y and T98G Cells via Different Cellular Mechanisms

Autor: Katarina Dibdiakova, Eva Vidomanová, Ivana Pilchova, Jozef Hatok, Lucia Lichardusova, Peter Racay, Katarina Klacanova, Simona Saksonova, Andrea Štefaniková

Publikováno v: Neurochemical Research. 42:3170-3185

Overload or dysfunction of ubiquitin-proteasome system (UPS) is implicated in mechanisms of neurodegeneration associated with neurodegenerative diseases, e.g. Parkinson and Alzheimer disease, and ischemia-reperfusion injury. The aim of this study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503237aa650bbdd826575fe376309fa3
https://doi.org/10.1007/s11064-017-2355-0

Zobrazit plný text záznamu

Cyclin-dependent kinase 2 inhibitor SU9516 increases sensitivity of colorectal carcinoma cells Caco-2 but not HT29 to BH3 mimetic ABT-737

Autor: Peter Racay, Ivana Pilchova, Andrea Štefaniková, Jozef Hatok, Katarina Klacanova

Publikováno v: General physiology and biophysics. 36:539-547

Colorectal carcinoma (CRC) that represents one of the major causes for cancer-related death in humans is often associated with over-expression of anti-apoptotic proteins of Bcl-2 family. The aim of presented study was to determine the effect of ABT-7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00e6afeaf5e4aea80e617f1fbfc32d4
https://doi.org/10.4149/gpb_2017030

Zobrazit plný text záznamu

SNPs rs11240569, rs708727, and rs823156 in SLC41A1 Do Not Discriminate Between Slovak Patients with Idiopathic Parkinson’s Disease and Healthy Controls: Statistics and Machine-Learning Evidence

Autor: Martin Kolisek, Maria Brodnanova, Oto Osina, Michal Cibulka, Marian Grendar, Ivana Pilchova, Milan Grofik, Dusan Dobrota, Zuzana Tatarkova, Egon Kurča

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 19
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4688 (2019)

Gene SLC41A1 (A1) is localized within Parkinson&rsquo
s disease-(PD)-susceptibility locus PARK16 and encodes for the Na+/Mg2+-exchanger. The association of several A1 SNPs with PD has been studied. Two, rs11240569 and rs823156, have been associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c736ef0a69f0aa0d755d97ccde0518

Zobrazit plný text záznamu

Plný text ve formátu HTML

Microfluidic profiling of apoptosis-related genes after treatment with BH3-mimetic agents in astrocyte and glioblastoma cell lines

Autor: Ivana Pilchova, Erika Halasova, Peter Racay, Eva Vidomanová, Jozef Hatok

Publikováno v: Oncology Reports. 36:3188-3196

Glioblastoma (GB) is the most frequent and biologically the most aggressive primary brain tumor in adults. Standard treatment for newly diagnosed GB consists of surgical resection, radiotherapy and chemotherapy. Resistance to therapy is a major obsta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a947df8550ba5706e6b20789ac55083
https://doi.org/10.3892/or.2016.5191

Zobrazit plný text záznamu

The Role of Heat Shock Proteins in Leukemia

Autor: Peter Racay, Dusan Dobrota, Ivana Pilchova, Jozef Hatok, Katarína Kliková, Andrea Štefaniková

Publikováno v: Klinicka onkologie. 29:29-38

Heat shock proteins (HSPs) HSP27, HSP70 and HSP90 are molecular chaperones; their expression is increased after exposure of cells to conditions of environmental stress, including heat shock, heavy metals, oxidative stress, or pathologic conditions, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cc83ceea859d32bd2910c80c7d1208
https://doi.org/10.14735/amko201629

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání