Differential Signature of the Centrosomal MARK4 Isoforms in Glioma

Autor: Ivana Magnani, Chiara Novielli, Laura Fontana, Silvia Tabano, Davide Rovina, Ramona F. Moroni, Dario Bauer, Stefania Mazzoleni, Elisa A. Colombo, Gabriella Tedeschi, Laura Monti, Giovanni Porta, Silvano Bosari, Carolina Frassoni, Rossella Galli, Lorenzo Bello, Lidia Larizza

Publikováno v: Analytical Cellular Pathology, Vol 34, Iss 6, Pp 319-338 (2011)

Background: MAP/microtubule affinity-regulating kinase 4 (MARK4) is a serine-threonine kinase expressed in two spliced isoforms, MARK4L and MARK4S, of which MARK4L is a candidate for a role in neoplastic transformation. Methods: We performed mutation

Externí odkaz: https://doaj.org/article/3ecf17df987948d4be7f551ce0a409e5

Spontaneous chromosomal instability in peripheral blood lymphocytes from two molecularly confirmed Italian patients with Hereditary Fibrosis Poikiloderma: insights into cancer predisposition

Autor: Cristina Gervasini, Ivana Magnani, Lidia Larizza, Mauro Paradisi, Gaia Roversi, Elisa Colombo, Giuseppe Maggiore

Publikováno v: Genetics and Molecular Biology
Genetics and Molecular Biology v.44 n.3 2021
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Vol 44, Iss 3 (2021)
Genetics and Molecular Biology, Volume: 44, Issue: 3, Article number: e20200332, Published: 06 AUG 2021

Two Italian patients with the initial clinical diagnosis of Rothmund-Thomson syndrome were negative for RECQL4 mutations but showed in peripheral blood cells a spontaneous chromosomal instability significantly higher than controls. Revisiting after t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8dd9627e6862afb8b9eebc3a9af1dc
https://pubmed.ncbi.nlm.nih.gov/34358284

Ukrain modulates glial fibrillary acidic protein, but not connexin 43 expression, and induces apoptosis in human cultured glioblastoma cells

Autor: Ivana Magnani, Wassil Nowicky, C. Torri, Francesco Costa, Nicoletta Gagliano, Claudia Moscheni, Magda Gioia, Elena Donetti

Publikováno v: Anti-Cancer Drugs. 18:669-676

Glioblastoma is a highly malignant tumor, characterized by an unfavorable prognosis even in response to multidisciplinary treatment strategies, owing to its high-invasive phenotype. Ukrain, a semisynthetic thiophosphoric acid derivative of the purifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1222aae1ecb3d08ae55ff631e2a27d24
https://doi.org/10.1097/cad.0b013e32808bf9ec

Molecular structure and evolution of DNA sequences located at the alpha satellite boundary of chromosome 20

Autor: Ivana Magnani, C. Bassi, Anna Marozzi, A. Ventura, Raffaella Meneveri, Nicoletta Sacchi, Enrico Ginelli, Mariano Rocchi, Salvatore Saccone

Publikováno v: Gene. 256:43-50

We have isolated and characterised one PAC clone (dJ233C1) containing a linkage between alphoid and non-alphoid DNA. The non-alphoid DNA was found to map at the pericentromeric region of chromosome 20, both on p and q sides, and to contain homologies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b2a915a7ba7c990d09d4b26bf8dd32
https://doi.org/10.1016/s0378-1119(00)00354-1

Reversible macrophage differentiation induced in a new human myeloid cell line by gamma interferon

Autor: Alberto Clivio, Cinzia Paini, Ivana Magnani, Claudia Pintér

Publikováno v: Cell Biology International. 19:9-16

A new cell line was established from the bone marrow of a patient with chronic myeloid leukemia. The cells were attributed an intermediate myeloid phenotype on the basis of their cytochemical features and membrane antigen expression. These cells resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cff4871e1b93bd8492bec3fe6cb849
https://doi.org/10.1006/cbir.1995.1002