Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ivana M. Djuretic"'
Autor:
Anjana Rao, Alex Pellerin, Catherine Trivigno, Thaddeus J. Carlson, Mark S. Sundrud, Sergei B. Koralov, Ivana M. Djuretic
Publikováno v:
The Journal of Immunology. 192:2167-2176
The IL-23 pathway is genetically linked to autoimmune disease in humans and is required for pathogenic Th17 cell function in mice. However, because IL-23R–expressing mature Th17 cells are rare and poorly defined in mice at steady-state, little is k
Autor:
Derya Unutmaz, Lina Kozhaya, Jacob L. McCauley, Kelly McKevitt, Ivana M. Djuretic, Maria T. Abreu, Mark S. Sundrud, Radha Ramesh, Maria A. Quintero, Thaddeus J. Carlson
Publikováno v:
The Journal of Experimental Medicine
Inflammatory T helper 17 cells in humans are distinguished by selective expression of MDR1 and are enriched in the gut of patients with Crohn’s disease.
IL-17A–expressing CD4+ T cells (Th17 cells) are generally regarded as key effectors of a
IL-17A–expressing CD4+ T cells (Th17 cells) are generally regarded as key effectors of a
Autor:
Pandurangan Vijayanand, Sarah Abdul-Wajid, Arlene H. Sharpe, Grégory Seumois, Xiaozhu Huang, Anjana Rao, Jeneen Interlandi, Dirk Baumjohann, Ivana M. Djuretic, Daniel R. Brown, K. Mark Ansel, Marisella Panduro, Laura J. Simpson
Publikováno v:
Immunity
SummaryFollicular helper T cells (Tfh cells) are the major producers of interleukin-4 (IL-4) in secondary lymphoid organs where humoral immune responses develop. Il4 regulation in Tfh cells appears distinct from the classical T helper 2 (Th2) cell pa
Autor:
Ivana M. Djuretic, Thaddeus J. Carlson, Derya Unutmaz, Qi Wan, Lina Kozhaya, Mark S. Sundrud, Aimee ElHed, Radha Ramesh
Publikováno v:
The Journal of Experimental Medicine
PI-3K–mediated repression of FOXO1 and KLF2 promotes proinflammatory cytokine expression by lineage-committed human CCR6+ Th17/Th22 memory cells.
Human memory T cells (TM cells) that produce IL-17 or IL-22 are currently defined as Th17 or Th22
Human memory T cells (TM cells) that produce IL-17 or IL-22 are currently defined as Th17 or Th22
Autor:
Anjana Rao, Fernando Cruz-Guilloty, Matthew E. Pipkin, Yoram Groner, Joseph Lotem, Ivana M. Djuretic, Ditsa Levanon, Mathias G. Lichtenheld
Publikováno v:
The Journal of Experimental Medicine
Activation of naive CD8+ T cells with antigen induces their differentiation into effector cytolytic T lymphocytes (CTLs). CTLs lyse infected or aberrant target cells by exocytosis of lytic granules containing the pore-forming protein perforin and a f
Autor:
K. Mark Ansel, Rebecca J. Greenwald, Suneet Agarwal, Craig H. Bassing, Arlene H. Sharpe, Anjana Rao, Dong U. Lee, Frederick W. Alt, Ivana M. Djuretic, Silvia Monticelli, Jeneen Interlandi
Publikováno v:
Nature Immunology. 5:1251-1259
Helper T cell differentiation involves silencing as well as activation of gene expression. We have identified a conserved silencer of the gene encoding interleukin 4 (Il4) marked by DNase I hypersensitivity (HS IV) and permissive chromatin structure
Publikováno v:
Advances in immunology. 104
Members of the Runx family of transcription factors, Runx1-3, are essential regulators of the immune system: a deficiency in one of the members, Runx1, results in complete ablation of hematopoiesis, and all three Runx proteins play important, nonredu
Members of the Runx family of transcription factors, Runx1-3, are essential regulators of the immune system: a deficiency in one of the members, Runx1, results in complete ablation of hematopoiesis, and all three Runx proteins play important, nonredu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ea424afab03a7bf200a492ce055c03a
https://doi.org/10.1016/s0065-2776(08)04001-7
https://doi.org/10.1016/s0065-2776(08)04001-7
Publikováno v:
Trends in immunology. 28(8)
A general theme in gene regulation is that transcription factors never function alone. Recent studies have emphasized this concept for regulatory T cells, a unique lineage of CD4+ T cells that exert active immune suppression and are essential to main
Publikováno v:
Nature immunology. 8(2)
Cell differentiation involves activation and silencing of lineage-specific genes. Here we show that the transcription factor Runx3 is induced in T helper type 1 (T(H)1) cells in a T-bet-dependent manner, and that both transcription factors T-bet and