Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Ivana K, Kim"'
Autor:
Bing Wu, Hayley M. Bennett, Xin Ye, Akshayalakshmi Sridhar, Celine Eidenschenk, Christine Everett, Evgeniya V. Nazarova, Hsu-Hsin Chen, Ivana K. Kim, Margaret Deangelis, Leah A. Owen, Cynthia Chen, Julia Lau, Minyi Shi, Jessica M. Lund, Ana Xavier-Magalhães, Neha Patel, Yuxin Liang, Zora Modrusan, Spyros Darmanis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Multiomic profiling of single cells by sequencing is a powerful technique for investigating cellular diversity. Existing droplet-based microfluidic methods produce many cell-free droplets, underutilizing bead barcodes and reagents. Combinato
Externí odkaz:
https://doaj.org/article/8f7c0a3ec95940b8a83501d58f25ab55
Autor:
Ines Lains, MD, PhD, Xikun Han, PhD, João Gil, MD, Joana Providencia, MD, Archana Nigalye, MD, Rodrigo Alvarez, MD, Vivian Paraskevi Douglas, MD, Kevin Mendez, MSc, Raviv Katz, BSc, Gregory Tsougranis, BSc, Jinglun Li, BSc, Rachel S. Kelly, PhD, Ivana K. Kim, MD, Jessica Lasky-Su, ScD, Rufino Silva, MD, PhD, Joan W. Miller, MD, Liming Liang, PhD, Demetrios Vavvas, MD, PhD, John B. Miller, MD, Deeba Husain, MD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 1, Pp 100357- (2024)
Purpose: The most widely used classifications of age-related macular degeneration (AMD) and its severity stages still rely on color fundus photographs (CFPs). However, AMD has a wide phenotypic variability that remains poorly understood and is better
Externí odkaz:
https://doaj.org/article/f85fa775aca54aa681cfe9965278b9bf
Autor:
Victor S. M. C. Correa, Nikolaos E. Efstathiou, Dimitrios P. Ntentakis, Zhen Yu, Toshio Narimatsu, Evangelos Gragoudas, Ivana K. Kim, Demetrios G. Vavvas
Publikováno v:
FEBS Open Bio, Vol 13, Iss 3, Pp 545-555 (2023)
Uveal melanoma (UM) is the most common primary intraocular cancer in the adult population. Recent studies suggested that the NLRP3 inflammasome could be a therapeutic target for cutaneous melanoma (CM), but the role of NLRP3 in UM remains unknown. He
Externí odkaz:
https://doaj.org/article/2b15d55188dc4325a2431a9d3f784964
Autor:
Vishal Raval, Elaine Binkley, Mary E. Aronow, Juan Valenzuela, David M. Peereboom, Wei Wei, Sunil Srivastava, Jaqueline Davanzo, Herbert Culver Boldt, Mark P. McGarrey, George N. Papaliodis, Lucia Sobrin, Ivana K. Kim, Dimitrios G. Vavvas, Dean Eliott, Lakshmi Nayak, Emilio Dodds, Francisco Marco del Pont, Arun D. Singh
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 362-370 (2022)
Abstract There is limited understanding of the inter‐compartmental progression and treatment outcomes of primary central nervous system lymphoma (PCNSL). In this multicenter retrospective cohort study on 234 patients with PCNSL (median age: 62.5 ye
Externí odkaz:
https://doaj.org/article/be506312b9b24579ace478741d438474
Autor:
Treefa Shwani, Charles Zhang, Leah A. Owen, Akbar Shakoor, Albert T. Vitale, John H. Lillvis, Julie L. Barr, Parker Cromwell, Robert Finley, Nadine Husami, Elizabeth Au, Rylee A. Zavala, Elijah C. Graves, Sarah X. Zhang, Michael H. Farkas, David A. Ammar, Karen M. Allison, Amany Tawfik, Richard M. Sherva, Mingyao Li, Dwight Stambolian, Ivana K. Kim, Lindsay A. Farrer, Margaret M. DeAngelis
Publikováno v:
Cells, Vol 12, Iss 23, p 2668 (2023)
Age-related macular degeneration (AMD) is a leading cause of blindness, and elucidating its underlying disease mechanisms is vital to the development of appropriate therapeutics. We identified differentially expressed genes (DEGs) and differentially
Externí odkaz:
https://doaj.org/article/e8beab75624a4f28ace7d19d17448129
Autor:
Ines Lains, MD, PhD, Shujian Zhu, MSc, Xikun Han, PhD, Wonil Chung, PhD, Qianyu Yuan, PhD, Rachel S. Kelly, PhD, Joao Q. Gil, MD, Raviv Katz, BSc, Archana Nigalye, MD, Ivana K. Kim, MD, John B. Miller, MD, Isabel M. Carreira, PhD, Rufino Silva, MD, PhD, Demetrios G. Vavvas, MD, PhD, Joan W. Miller, MD, Jessica Lasky-Su, ScD, Liming Liang, PhD, Deeba Husain, MD
Publikováno v:
Ophthalmology Science, Vol 1, Iss 1, Pp 100017- (2021)
Purpose: Large-scale genome-wide association studies (GWAS) have reported important single nucleotide polymorphisms (SNPs) with significant associations with age-related macular degeneration (AMD). However, their role in disease development remains e
Externí odkaz:
https://doaj.org/article/83f0634a0e074da1aaf7847366726755
Autor:
Victor S. M. C. Correa, Nikolaos E. Efstathiou, Dimitrios P. Ntentakis, Zhen Yu, Toshio Narimatsu, Evangelos Gragoudas, Ivana K. Kim, Demetrios G. Vavvas
Publikováno v:
FEBS Open Bio. 13:545-555
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34187d73327987c517bffdaa10df0f93
https://doi.org/10.1002/2211-5463.13566
https://doi.org/10.1002/2211-5463.13566
Autor:
Alexei V. Trofimov, Mary E. Aronow, Evangelos S. Gragoudas, Florence K. Keane, Ivana K. Kim, Helen A. Shih, Mandar S. Bhagwat
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:501-510
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fca8df513bc16be0138db750aabcf2c7
https://doi.org/10.1016/j.ijrobp.2022.07.017
https://doi.org/10.1016/j.ijrobp.2022.07.017
Autor:
Ines Lains, Kevin Mendez, Archana Nigalye, Raviv Katz, Vivian Paraskevi Douglas, Rachel S. Kelly, Ivana K. Kim, John B. Miller, Demetrios G. Vavvas, Liming Liang, Jessica Lasky-Su, Joan W. Miller, Deeba Husain
Publikováno v:
Metabolites, Vol 12, Iss 1, p 32 (2022)
Plasma metabolomic profiles have been shown to be associated with age-related macular degeneration (AMD) and its severity stages. However, all studies performed to date have been cross-sectional and have not assessed progression of AMD. This prospect
Externí odkaz:
https://doaj.org/article/a517c846729041e291338ad0370c538a
Autor:
Yara A. Samra, Dina Kira, Pragya Rajpurohit, Riyaz Mohamed, Leah A. Owen, Akbar Shakoor, Ivana K. Kim, Margaret M. DeAngelis, Nader Sheibani, Mohamed Al-Shabrawey, Amany Tawfik
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9356 (2021)
Age-related macular degeneration (AMD) is a leading cause of vision loss. Elevated homocysteine (Hcy) (Hyperhomocysteinemia) (HHcy) has been reported in AMD. We previously reported that HHcy induces AMD-like features. This study suggests that N-Methy
Externí odkaz:
https://doaj.org/article/63bd407e310049c183a5d5caee944a14