Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Ivana Jarak"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7577 (2024)
Colorectal cancer (CRC) is the third most prominent cancer worldwide, and the second leading cause of cancer death. Poor outcomes and limitations of current treatments fuel the search for new therapeutic options. Curcumin (CUR) is often presented as
Externí odkaz:
https://doaj.org/article/63a8cf9a6c304c998decfbd3f5cc08f8
Autor:
Catarina Santos, Rui Carvalho, Ana Mafalda Fonseca, Miguel Castelo Branco, Marco Alves, Ivana Jarak
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3416 (2024)
In arterial hypertension, the dysregulation of several metabolic pathways is closely associated with chronic immune imbalance and inflammation progression. With time, these disturbances lead to the development of progressive disease and end-organ inv
Externí odkaz:
https://doaj.org/article/4f0edab4647d4af09b2d38b9d93aecb1
Autor:
Mariana Fonseca, Ivana Jarak, Francis Victor, Cátia Domingues, Francisco Veiga, Ana Figueiras
Publikováno v:
Materials, Vol 17, Iss 2, p 319 (2024)
Polymersomes are artificial nanoparticles formed by the self-assembly process of amphiphilic block copolymers composed of hydrophobic and hydrophilic blocks. They can encapsulate hydrophilic molecules in the aqueous core and hydrophobic molecules wit
Externí odkaz:
https://doaj.org/article/76d2d5fc752a4c979bf2f4ccf29589c8
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2431 (2023)
The paradigm of pediatric drug development has been evolving in a “carrot-and-stick”-based tactic to address population-specific issues. However, the off-label prescription of adult medicines to pediatric patients remains a feature of clinical pr
Externí odkaz:
https://doaj.org/article/0dd6a016563244458c2a10f3529a1ede
Publikováno v:
Plants, Vol 12, Iss 15, p 2869 (2023)
Tamarillo is a solanaceous tree that has been extensively studied in terms of in vitro clonal propagation, namely somatic embryogenesis. In this work, a protocol of indirect somatic embryogenesis was applied to obtain embryogenic and non-embryogenic
Externí odkaz:
https://doaj.org/article/84d7e92164db4101b737f7226c05ae23
Autor:
Maria João Meneses, Inês Sousa-Lima, Ivana Jarak, João F. Raposo, Marco G. Alves, Maria Paula Macedo
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveIn the last years, changes in dietary habits have contributed to the increasing prevalence of metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM). The differential burden of lipids and f
Externí odkaz:
https://doaj.org/article/50528a9933bd4927b21b9b7f0bd2f022
Autor:
Luís Crisóstomo, Ivana Jarak, Luís P. Rato, João F. Raposo, Rachel L. Batterham, Pedro F. Oliveira, Marco G. Alves
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The consumption of energy-dense diets has contributed to an increase in the prevalence of obesity and its comorbidities worldwide. The adoption of unhealthy feeding habits often occurs at early age, prompting the early onset of metabolic dis
Externí odkaz:
https://doaj.org/article/0924abf5ce114ed5bd4bb4448af4b070
Autor:
Cátia Domingues, Cristiana Cabral, Ivana Jarak, Francisco Veiga, Marília Dourado, Ana Figueiras
Publikováno v:
Vaccines, Vol 11, Iss 3, p 492 (2023)
The human microbiota comprises a group of microorganisms co-existing in the human body. Unbalanced microbiota homeostasis may impact metabolic and immune system regulation, shrinking the edge between health and disease. Recently, the microbiota has b
Externí odkaz:
https://doaj.org/article/3528cdad46864b6d981c5ba04e0bf4e6
Autor:
Beatriz Almeida, Cátia Domingues, Filipa Mascarenhas-Melo, Inês Silva, Ivana Jarak, Francisco Veiga, Ana Figueiras
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2974 (2023)
Coronavirus disease-19 (COVID-19) emerged in December 2019 and quickly spread, giving rise to a pandemic crisis. Therefore, it triggered tireless efforts to identify the mechanisms of the disease, how to prevent and treat it, and to limit and hamper
Externí odkaz:
https://doaj.org/article/d3cbd47f62314a9db25f42802e3455cd
Autor:
Inês Silva, Cátia Domingues, Ivana Jarak, Rui A. Carvalho, Rosemeyre A. Cordeiro, Marília Dourado, Francisco Veiga, Henrique Faneca, Ana Figueiras
Publikováno v:
Polymers, Vol 14, Iss 23, p 5315 (2022)
Copolymers composed of low-molecular-weight polyethylenimine (PEI) and amphiphilic Pluronics® are safe and efficient non-viral vectors for pDNA transfection. A variety of Pluronic® properties provides a base for tailoring transfection efficacy in c
Externí odkaz:
https://doaj.org/article/47720cf1d5c04af094fda498301ac52c