Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Ivana Hermanova"'
1
Akademický článek
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
Autor: Jan Pencik, Cecile Philippe, Michaela Schlederer, Emine Atas, Matteo Pecoraro, Sandra Grund-Gröschke, Wen (Jess) Li, Amanda Tracz, Isabel Heidegger, Sabine Lagger, Karolína Trachtová, Monika Oberhuber, Ellen Heitzer, Osman Aksoy, Heidi A. Neubauer, Bettina Wingelhofer, Anna Orlova, Nadine Witzeneder, Thomas Dillinger, Elisa Redl, Georg Greiner, David D’Andrea, Johnny R. Östman, Simone Tangermann, Ivana Hermanova, Georg Schäfer, Felix Sternberg, Elena E. Pohl, Christina Sternberg, Adam Varady, Jaqueline Horvath, Dagmar Stoiber, Tim I. Malcolm, Suzanne D. Turner, Eileen E. Parkes, Brigitte Hantusch, Gerda Egger, Stefan Rose-John, Valeria Poli, Suneil Jain, Chris W. D. Armstrong, Gregor Hoermann, Vincent Goffin, Fritz Aberger, Richard Moriggl, Arkaitz Carracedo, Cathal McKinney, Richard D. Kennedy, Helmut Klocker, Michael R. Speicher, Dean G. Tang, Ali A. Moazzami, David M. Heery, Marcus Hacker, Lukas Kenner
Publikováno v: Molecular Cancer, Vol 22, Iss 1, Pp 1-25 (2023)
Abstract Prostate cancer (PCa) is a common and fatal type of cancer in men. Metastatic PCa (mPCa) is a major factor contributing to its lethality, although the mechanisms remain poorly understood. PTEN is one of the most frequently deleted genes in m
Externí odkaz: https://doaj.org/article/55713eefba5d493d89c7d396451b3eb7
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4
Akademický článek
PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to l-asparaginase
Autor: Katerina Hlozkova, Ivana Hermanova, Lucie Safrhansova, Natividad Alquezar-Artieda, Daniela Kuzilkova, Adela Vavrova, Kristyna Sperkova, Marketa Zaliova, Jan Stary, Jan Trka, Julia Starkova
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Childhood T-cell acute lymphoblastic leukemia (T-ALL) still remains a therapeutic challenge due to relapses which are resistant to further treatment. l-asparaginase (ASNase) is a key therapy component in pediatric T-ALL and lower sensitivity
Externí odkaz: https://doaj.org/article/a56a66429e434579a86547fe963c8f4f
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5
Akademický článek
Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling
Autor: Julia Starkova, Sharvari Gadgil, Yi Hua Qiu, Nianxiang Zhang, Ivana Hermanova, Steven M. Kornblau, Harry A. Drabkin
Publikováno v: Haematologica, Vol 96, Iss 6 (2011)
Background Activating mutations in fms-like tyrosine kinase-3 (FLT3) are frequent in acute myeloid leukemia and represent both a poor prognostic feature and a therapeutic target. We have identified a previously unrecognized downstream effect of FLT3
Externí odkaz: https://doaj.org/article/3c1f03b08c87411b8d04a14697111256
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