Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Ivana Gudelj"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Microbial secretions, such as metabolic enzymes, are often considered to be cooperative public goods as they are costly to produce but can be exploited by others. They create incentives for the evolution of non-producers, which can drive pro
Externí odkaz:
https://doaj.org/article/61f9305b13894c99a71c43b3663783f8
Autor:
Pablo Catalán, Emily Wood, Jessica M. A. Blair, Ivana Gudelj, Jonathan R. Iredell, Robert E. Beardmore
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Pathogens are typically classified as ‘antibiotic-resistant’ for clinical purposes based on cut-off values of minimum inhibitory concentrations (MICs). In this study, the authors explore quantitative values of MICs using the global ‘ATLAS’ da
Externí odkaz:
https://doaj.org/article/554efb0606b5483784bf9d3ba61d6eca
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Pneumocystis jirovecii kills hundreds of thousands of immunocompromised patients each year. Yet many aspects of the biology of this obligate pathogen remain obscure because it is not possible to culture the fungus in vitro independently of i
Externí odkaz:
https://doaj.org/article/d6a323f64b1446f6ba06f3d198b87b7a
Publikováno v:
The Holistic Approach to Environment, Vol 9, Iss 3, Pp 60-69 (2019)
Increasing number of tourists wants to experience nature and at the same time have a positive impact on nature during their tourist stay. This paper presents the relationship between the preservation of natural capital of the locality and tourist sea
Externí odkaz:
https://doaj.org/article/d85de3c5d5704de8bc5b93f1127ea8a6
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 3, p e1008817 (2021)
Developing mathematical models to accurately predict microbial growth dynamics remains a key challenge in ecology, evolution, biotechnology, and public health. To reproduce and grow, microbes need to take up essential nutrients from the environment,
Externí odkaz:
https://doaj.org/article/99a8c7e10d0b4f16b6bb4b353157e675
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT The amount of natural resources in the Earth’s environment is in flux, which can trigger catastrophic collapses of ecosystems. How populations survive under nutrient-poor conditions is a central question in ecology. Curiously, some bacteri
Externí odkaz:
https://doaj.org/article/d3d30fb4daf34690b1ebf62dcfb2bdd0
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 12, p e1005269 (2016)
Cross-feeding, a relationship wherein one organism consumes metabolites excreted by another, is a ubiquitous feature of natural and clinically-relevant microbial communities and could be a key factor promoting diversity in extreme and/or nutrient-poo
Externí odkaz:
https://doaj.org/article/e7fcd1738c2b4f258a8810701a7188bf
Publikováno v:
eLife, Vol 5 (2016)
Existing theory, empirical, clinical and field research all predict that reducing the virulence of individuals within a pathogen population will reduce the overall virulence, rendering disease less severe. Here, we show that this seemingly successful
Externí odkaz:
https://doaj.org/article/6d1c089e2d99428f9fd717658b516936
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 11, p e1005216 (2016)
Many antimicrobial and anti-tumour drugs elicit hormetic responses characterised by low-dose stimulation and high-dose inhibition. While this can have profound consequences for human health, with low drug concentrations actually stimulating pathogen
Externí odkaz:
https://doaj.org/article/95fc96b8448a44f6939959eb48e03750
Autor:
Ayari Fuentes-Hernandez, Jessica Plucain, Fabio Gori, Rafael Pena-Miller, Carlos Reding, Gunther Jansen, Hinrich Schulenburg, Ivana Gudelj, Robert Beardmore
Publikováno v:
PLoS Biology, Vol 13, Iss 4, p e1002104 (2015)
We need to find ways of enhancing the potency of existing antibiotics, and, with this in mind, we begin with an unusual question: how low can antibiotic dosages be and yet bacterial clearance still be observed? Seeking to optimise the simultaneous us
Externí odkaz:
https://doaj.org/article/7741a185edc84b788c3451d9ddb55634