Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ivana Gaziova"'
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009011 (2020)
Neuronal precursor cells undergo self-renewing and non-self-renewing asymmetric divisions to generate a large number of neurons of distinct identities. In Drosophila, primary precursor neuroblasts undergo a varying number of self-renewing asymmetric
Externí odkaz:
https://doaj.org/article/d40374b2ebcf4a63858c610b26cfdbb4
Autor:
Ivana Gaziova, Daniel Jackson, Paul J Boor, Dwayne Carter, Zobeida Cruz-Monserrate, Cornelis J Elferink, Aditya D Joshi, Bhupendra Kaphalia, Craig D Logsdon, Karen Pereira de Castro, Lynn Soong, Xinrong Tao, Suimin Qiu, Lisa A Elferink
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165485 (2016)
Acinar cells represent the primary target in necroinflammatory diseases of the pancreas, including pancreatitis. The signaling pathways guiding acinar cell repair and regeneration following injury remain poorly understood. The purpose of this study w
Externí odkaz:
https://doaj.org/article/418a58ff5b974aa3a5e84a139e093f08
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1004050 (2013)
Guiding axon growth cones towards their targets is a fundamental process that occurs in a developing nervous system. Several major signaling systems are involved in axon-guidance, and disruption of these systems causes axon-guidance defects. However,
Externí odkaz:
https://doaj.org/article/d2fc6a5546b24a1ca3eb468b0e1498db
Autor:
Kristen S Hill, Ivana Gaziova, Lindsay Harrigal, Yvette A Guerra, Suimin Qiu, Sarita K Sastry, Thiruvengadam Arumugam, Craig D Logsdon, Lisa A Elferink
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40420 (2012)
At diagnosis, the majority of pancreatic cancer patients present with advanced disease when curative resection is no longer feasible and current therapeutic treatments are largely ineffective. An improved understanding of molecular targets for effect
Externí odkaz:
https://doaj.org/article/05aea845a3fc4e81a54e166dd30e808f
Autor:
John Miller, Taylor Moncrief, Guy M. Benian, Ivana Gaziova, Courtney J. Matheny, Hiroshi Qadota, Andres F. Oberhauser
Publikováno v:
Protein Sci
Proper muscle development and function depend on myosin being properly folded and integrated into the thick filament structure. For this to occur the myosin chaperone UNC-45, or UNC-45B, must be present and able to chaperone myosin. Here we use a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3eb522ca3933bdb14d2ca583defd991
https://doi.org/10.1002/pro.4180
https://doi.org/10.1002/pro.4180
Autor:
Guy M. Benian, Courtney J. Christian, Simon Powell, Taylor Moncrief, Hubert Lee, Michael Villarreal, Hiroshi Qadota, Andres F. Oberhauser, Ivana Gaziova, Mark A. White
Publikováno v:
Biophys J
UNC-45B is a multidomain molecular chaperone that is essential for the proper folding and assembly of myosin into muscle thick filaments in vivo. It has previously been demonstrated that the UCS domain is responsible for the chaperone-like properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68371da99cb44f6095d2bd3e534cb601
https://doi.org/10.1016/j.bpj.2020.07.012
https://doi.org/10.1016/j.bpj.2020.07.012
Autor:
Guy M. Benian, Courtney J. Matheny, Ivana Gaziova, Hiroshi Qadota, Andres F. Oberhauser, Taylor Moncrief, John Miller
Proper muscle development and function depends on myosin being properly folded and integrated into the thick filament structure. For this to occur the myosin chaperone UNC-45, or UNC-45B, must be present and able to chaperone myosin. Here we use a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e8644431c0d801ab36aa54fc884d34
https://doi.org/10.1101/2021.05.07.443121
https://doi.org/10.1101/2021.05.07.443121
Autor:
Mark A. White, Guy M. Benian, Courtney J. Christian, Taylor Moncrief, Simon Powell, Michael Villarreal, Andres F. Oberhauser, Hiroshi Qadota, Ivana Gaziova
UNC-45B is a multidomain molecular chaperone that is essential for the proper folding and assembly of myosin into muscle thick filamentsin vivo. We have previously demonstrated that its UCS domain is responsible for the chaperone-like properties of U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1e74cf4a9a4ff9f4345fe810ea6348
Autor:
Cornelis J. Elferink, Zobeida Cruz-Monserrate, Bhupendra S. Kaphalia, Karen Pereira de Castro, Lisa A. Elferink, Lynn Soong, Aditya D. Joshi, Dwayne Carter, Paul J. Boor, Daniel Jackson, Craig D. Logsdon, Xinrong Tao, Ivana Gaziova, Suimin Qiu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0165485 (2016)
PLoS ONE, Vol 11, Iss 10, p e0165485 (2016)
Acinar cells represent the primary target in necroinflammatory diseases of the pancreas, including pancreatitis. The signaling pathways guiding acinar cell repair and regeneration following injury remain poorly understood. The purpose of this study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e39b365b14ef66dcd51a240996d346
https://pubmed.ncbi.nlm.nih.gov/27798657
https://pubmed.ncbi.nlm.nih.gov/27798657
Publikováno v:
Developmental Biology. 351(1):186-198
In the CNS, the evolutionarily conserved Notch pathway regulates asymmetric cell fate specification to daughters of ganglion mother cells (GMCs). The E3 Ubiquitin ligase protein Neuralized (Neur) is thought to activate Notch-signaling by the endocyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54120720e44d256b9405ac145d8f6c18