Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ivana Cvetanovic"'
Publikováno v:
American Journal of Therapeutics. 12:328-336
Many drugs are proarrhythmic by inhibiting the cardiac rapid delayed rectifier potassium channel (IKr). In this study, we use quinidine as an example of highly proarrhythmic agent to investigate the risk factors that may facilitate the proarrhythmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9422aa9fcedc493eac2b706a28b4347e
https://doi.org/10.1097/01.mjt.0000143698.53038.1b
https://doi.org/10.1097/01.mjt.0000143698.53038.1b
Autor:
H. Caroline Gertzen, I. Blankoff, Christian Torp-Pedersen, Stephane Carlier, Vedat Davutoglu, Ozlem Soran, Judeen Camacho, Lisette Okkels Jensen, Janos Molnar, Liang-Yu Lin, Claudia Abletshauser, Meir Antopolsky, Gergana Stoschitzky, Giuseppe Tarantini, Tova Chajek-Shaul, Kirsten Tolstrup, Jens Haarbo, Paolo Bruzzi, Kemal Yeşilçimen, Sabino Iliceto, Helmut Brussee, S.E. Haine, Stephen D. Greenwood, C.J. Vrints, Bo E. Madsen, Ayşe Emre, Robert J. Siegel, Per Thayssen, Serdar Soydinc, Harald Dobnig, Gary S. Mintz, John C. Somberg, Peter A. Smars, V. Ranade, Yen-Wen Wu, Jai-Wun Park, Hubert Scharnagl, Ming-Fong Chen, Torben Haghfelt, Domenico Scrutinio, David Leibowitz, Monika Vogel, Juey-Jen Hwang, Jawdat Abdulla, Birsen Ersek, H.P. Miljoen, Jose A. Ruiz, Mehmet Aksoy, Lars Køber, Jiunn-Lee Lin, Ivana Cvetanovic, Knud Erik Pedersen, Tamer Akbulut, Tatjana Stojakovic, Luca Boni, Winfried März, Ayhan Dundar, Zita Molnar, Dilaver Oz, Claudia Bonell, Tal Hasin, Kurt Stoschitzky, Hsiang-Yiang Jui, Sait Terzi, Nurten Sayar, Franz Freisinger, Paolo Rizzon, Chii-Ming Lee, Yuan-Teh Lee, Tuba Bilsel, Jou-Wei Lin, Ekrem Ucer
Publikováno v:
Cardiology. 106:283-285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d89dd3c078cc5a2b31f61fa3e62110d
https://doi.org/10.1159/000097150
https://doi.org/10.1159/000097150
Publikováno v:
Journal of cardiovascular pharmacology and therapeutics. 17(1)
Females are more susceptible to drug-induced torsade de pointes (TdP), which is associated with excessive prolongation of the heart rate-corrected QT interval (QTc). Sotalol prolongs the cardiac action potential that can be observed as QT prolongatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08c6fdd524531ce42c4ab543959d422
https://pubmed.ncbi.nlm.nih.gov/21527783
https://pubmed.ncbi.nlm.nih.gov/21527783
Publikováno v:
American journal of therapeutics. 14(3)
Smooth-muscle erg 1 (erg1-sm) potassium channel has been recently reported to participate in the modulation of gastrointestinal contractility. Because quinidine inhibits cardiac potassium channel and as a result augments gastrointestinal contractilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da3244c3514f82305edec3c50faed3c
https://pubmed.ncbi.nlm.nih.gov/17515703
https://pubmed.ncbi.nlm.nih.gov/17515703
Publikováno v:
American journal of therapeutics. 14(1)
Background and objectives This study was design to compare the diuretic and natriuretic effects of the 2 parenteral formulations of metolazone and the combination of these 2 formulations of metolazone with the parenteral administration of furosemide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ae46857b0a53d4a6c7dfd5f4dcfe2f
https://pubmed.ncbi.nlm.nih.gov/17303972
https://pubmed.ncbi.nlm.nih.gov/17303972
Publikováno v:
Cardiology. 106(4)
Background: Drug induced QT prolongation may precipitate life threatening cardiac arrhythmias. Evaluation of the QT prolonging effect of new pharmaceutical agents in a ‘thorough QT/QTc study’ is being mandated by FDA. The purpose of this study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062917e9145589c83f087ced12c619e6
https://pubmed.ncbi.nlm.nih.gov/16685129
https://pubmed.ncbi.nlm.nih.gov/16685129
Publikováno v:
Cardiology. 108(1)
Background: Hyperkalemia is a potentially life-threatening disorder frequently occurring in hospitalized patients. The ischemic myocardium releases potassium into the extracellular space which can cause regional hyperkalemia. These changes may modify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8daeef82b293a49a484f645c1d96038d
https://pubmed.ncbi.nlm.nih.gov/16960444
https://pubmed.ncbi.nlm.nih.gov/16960444
Publikováno v:
American journal of therapeutics. 12(3)
To evaluate the electrophysiologic and antiarrhythmic effects, Mg was infused at 15 mg/h (n = 5) or an equal volume of saline (1.2 mL/h) (n = 5) and electrocardiogram and action potential duration (APD) recorded every 15 minutes. Rats were anesthetiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5753e78a5b40e1929cebe181805fa1a
https://pubmed.ncbi.nlm.nih.gov/15891264
https://pubmed.ncbi.nlm.nih.gov/15891264
Publikováno v:
Journal of cardiovascular pharmacology and therapeutics. 10(1)
Background: Myocardial infarction causes the acidification of the cellular environment and the resultant acidosis maybe arrhythmogenic. The effect of acidosis on the action of antiar-rhythmic drugs, an important issue in the antiarrhythmic drug thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d60f5143b5dd756bcc14b47a9c8cba
https://pubmed.ncbi.nlm.nih.gov/15821840
https://pubmed.ncbi.nlm.nih.gov/15821840
Publikováno v:
Cardiovascular drugs and therapy. 18(5)
Objective: This study was designed to test the hypothesis that rapid bolus administration of an aqueous formulation of intravenous amiodarone causes less hypotension than a 10-minute infusion of the standard formulation, Cordarone IV. Hypotension was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8177a16da8939fe721b4f39749ca7252
https://pubmed.ncbi.nlm.nih.gov/15717136
https://pubmed.ncbi.nlm.nih.gov/15717136