Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ivana Blaženović"'
Autor:
Xianhui Liu, Ivana Blaženović, Adam J. Contreras, Thu M. Pham, Christine A. Tabuloc, Ying H. Li, Jian Ji, Oliver Fiehn, Joanna C. Chiu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Misalignment between lifestyle and the natural day-night cycle, such as mistimed eating, can negatively impact health. Here the authors show that mistimed feeding alters protein O-GlcNAcylation, a nutrient sensitive post-translational modification.
Externí odkaz:
https://doaj.org/article/7dd753e5c95d4a248376025b6e768033
Autor:
Peter C. Hart, Hilary A. Kenny, Niklas Grassl, Karen M. Watters, Lacey M. Litchfield, Fabian Coscia, Ivana Blaženović, Lisa Ploetzky, Oliver Fiehn, Matthias Mann, Ernst Lengyel, Iris L. Romero
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4086-4098.e6 (2019)
Summary: The tumor microenvironment (TME) plays a pivotal role in cancer progression, and, in ovarian cancer (OvCa), the primary TME is the omentum. Here, we show that the diabetes drug metformin alters mesothelial cells in the omental microenvironme
Externí odkaz:
https://doaj.org/article/0997e8ecfa2743a797aa257846e3877d
Autor:
Ivana Blaženović, Tobias Kind, Hrvoje Torbašinović, Slobodan Obrenović, Sajjan S. Mehta, Hiroshi Tsugawa, Tobias Wermuth, Nicolas Schauer, Martina Jahn, Rebekka Biedendieck, Dieter Jahn, Oliver Fiehn
Publikováno v:
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-12 (2017)
Abstract In mass spectrometry-based untargeted metabolomics, rarely more than 30% of the compounds are identified. Without the true identity of these molecules it is impossible to draw conclusions about the biological mechanisms, pathway relationship
Externí odkaz:
https://doaj.org/article/5dc498693f11454097890d3dedafa18d
Autor:
Jelle Zwaag, Rob ter Horst, Ivana Blaženović, Daniel Stoessel, Jacqueline Ratter, Josephine M. Worseck, Nicolas Schauer, Rinke Stienstra, Mihai G. Netea, Dieter Jahn, Peter Pickkers, Matthijs Kox
Publikováno v:
Metabolites, Vol 10, Iss 4, p 148 (2020)
We recently demonstrated that the sympathetic nervous system can be voluntarily activated following a training program consisting of cold exposure, breathing exercises, and meditation. This resulted in profound attenuation of the systemic inflammator
Externí odkaz:
https://doaj.org/article/95fcf8e25ebc4586b931098f2ac2f2f9
Publikováno v:
Toxins, Vol 10, Iss 11, p 441 (2018)
Lipopolysaccharide (LPS) is the main virulence factor of Gram-negative bacteria, which can incite inflammation in tissues by inducing cells to secrete a variety of proinflammatory mediators, including cytokines, chemokines, interleukins, and prostagl
Externí odkaz:
https://doaj.org/article/e5037122f8dd4bfa8948a86ff6401a4e
Publikováno v:
Metabolites, Vol 8, Iss 2, p 31 (2018)
The annotation of small molecules remains a major challenge in untargeted mass spectrometry-based metabolomics. We here critically discuss structured elucidation approaches and software that are designed to help during the annotation of unknown compo
Externí odkaz:
https://doaj.org/article/ab74ece87082453a86fe96b054ec1287
Autor:
Joanna C. Chiu, Ivana Blaženović, Xianhui Liu, Thu M. Pham, Oliver Fiehn, Ying H. Li, Adam Contreras, Jian Ji, Christine A. Tabuloc
Publikováno v:
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The integration of circadian and metabolic signals is essential for maintaining robust circadian rhythms and ensuring efficient metabolism and energy use. Using Drosophila as an animal model, we show that cellular protein O-GlcNAcylation exhibits rob
Autor:
Jun Wang, Jian Ji, Chunyang Xu, Shiying Xu, Xiulan Sun, Lu Gao, Tingwei Wang, Ivana Blaženović
Publikováno v:
Addiction biologyREFERENCES. 26(6)
Methamphetamine (METH) abuse has become a global public health problem. However, the potential mechanisms involving METH-induced metabolic disorders have thus far remained poorly understood. Metabolomics can provide a clue for the cause of apparent c
Publikováno v:
Toxicon. 168:49-57
Ozone plays an increasingly important role in food processing for its antimicrobial ability and degradation effects on mycotoxins. The mycotoxin deoxynivalenol (DON) was treated with saturated aqueous ozone for different amounts of time, and by-produ
Autor:
Ivana Blaženović, Yinzhi Zhang, Xiulan Sun, Jian Ji, Hongyan Guo, Shuang Xia, Qiuyun Wang, Hao Wu
Publikováno v:
Food and Chemical Toxicology. 126:106-112
Metabolic profiling in Caco-2 cells was studied for the combined toxic effects of deoxynivalenol (DON), zearalenone (ZEN), and Aflatoxin B1 (AFB1) through untargeted GC-MS. The GC-MS spectra of Caco-2 cells treated with individual 6.7 μM DON, 20 μM