Výsledky vyhledávání - "Ivana Belén Alvarez"

Role Played by the Programmed Death‐1–Programmed Death Ligand Pathway during Innate Immunity againstMycobacterium tuberculosis

Autor: Ivana Belén Alvarez, Eduardo Abbate, Virginia Pasquinelli, Rosa M. Musella, Verónica E. García, Javier Oscar Jurado, Silvia de la Barrera

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Tuberculous pleurisy allows the study of specific cells at the site of Mycobacterium tuberculosis infection. Among pleural lymphocytes, natural killer (NK) cells are a major source of interferon γ (IFN-γ), and their functions are regulated by activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec38a70061c3c60dca5bd54915d059f4
https://doi.org/10.1086/654932

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IFN-γ Production during Active Tuberculosis Is Regulated by Mechanisms That Involve IL-17, SLAM, and CREB

Autor: María Florencia Quiroga, Peter F. Barnes, Virginia Pasquinelli, Ivana Belén Alvarez, Buka Samten, James C. Townsend, Javier Oscar Jurado, Verónica E. García

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Interferon-γ (IFN-γ) is crucial for protection against Mycobacterium tuberculosis, and the transcription factor cAMP response element binding protein (CREB) increases IFN-γ transcription. We determined whether the transmembrane receptor signaling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834ad1a55e33a6df8b0e3624bdfb9f00
https://doi.org/10.1086/596742

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Programmed Death (PD)-1:PD-Ligand 1/PD-Ligand 2 Pathway Inhibits T Cell Effector Functions during Human Tuberculosis

Autor: María Florencia Quiroga, Virginia Pasquinelli, Javier Oscar Jurado, Eduardo Abbate, Rosa M. Musella, H. Eduardo Chuluyan, Gustavo J. Martinez, Ivana Belén Alvarez, Verónica E. García

Publikováno v: The Journal of Immunology. 181:116-125

Protective immunity against Mycobacterium tuberculosis requires the generation of cell-mediated immunity. We investigated the expression and role of programmed death 1 (PD-1) and its ligands, molecules known to modulate T cell activation, in the regu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1add149c75cd569d714c3b7f07d6b045
https://doi.org/10.4049/jimmunol.181.1.116

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Phosphorylation of Mitogen-Activated Protein Kinases Contributes to Interferon γ Production in Response to Mycobacterium tuberculosis

Autor: Virginia Pasquinelli, Javier Oscar Jurado, Rosa M. Musella, Verónica E. García, Domingo Palmero, Ana Inés Rovetta, Ivana Belén Alvarez, Buka Samten, Peter F. Barnes, Alejandro Malbrán

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Immune control of Mycobacterium tuberculosis depends on interferon γ (IFN-γ)–producing CD4+ lymphocytes. Previous studies have shown that T cells from patients with tuberculosis produce less IFN-γ, compared with healthy donors, in response to my

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7297c391fb8cc64fc8bee526e9189ef
https://academic.oup.com/jid/article-lookup/doi/10.1093/infdis/jis672

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Early secreted antigenic target of 6-kDa protein of Mycobacterium tuberculosis primes dendritic cells to stimulate Th17 and inhibit Th1 immune responses

Autor: Pierre F. Neuenschwander, Xisheng Wang, Peter F. Barnes, Buka Samten, Fang-fang Huang, David R. Sherman, Ivana Belén Alvarez

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Early secreted antigenic target of 6 kDa (ESAT-6) of Mycobacterium tuberculosis is a T cell Ag that is a potential vaccine candidate, but it is also a virulence factor that mediates pathogenicity. To better understand the effects of ESAT-6 on the imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a9d3c5db47514933a1e8bfce5c272f
http://www.jimmunol.org/content/189/6/3092

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IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease

Autor: Nancy Liliana Tateosian, H. Eduardo Chuluyan, Ivana Belén Alvarez, Virginia Pasquinelli, Rosa M. Musella, Ana I. Rovetta, Horacio Eduardo Romeo, Domingo Palmero, Delfina Peña, Javier Oscar Jurado, Verónica E. García

Publikováno v: Journal of Leukocyte BiologyVol. 91. N° 6, 2012
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA

Fil: Jurado, Javier O. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina Fil: Pasquinelli, Virginia. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525ed02b7bc4e74d02ddfe7a047949e3
https://europepmc.org/articles/PMC3360475/

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CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis

Autor: Javier Oscar Jurado, Romina Haydeé Aspera, Virginia Pasquinelli, Rosa M. Musella, Ivana Belén Alvarez, Dario Fernandez Do Porto, Verónica E. García

Publikováno v: Immunology and Cell Biology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Protective immunity against Mycobacterium tuberculosis is primarily mediated by the interaction of antigen-specific T cells and antigen presenting cells, which often depends on the interplay of cytokines produced by these cells. Costimulatory signals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bb1e8de6a22631ed5859272a87d16c
Wiley Online Library

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