Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ivana, William"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/fe5bd7606c7644c597ea6e11abacdc02
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 87-88 (2023)
OBJECTIVES/GOALS: Glioblastoma (GBM) is the most common and aggressive adult primary brain malignancy. Clinically, GBM is refractory to T cell immune checkpoint blockade (ICB), in part due to its dense immune suppressive myeloid stroma. Here we show
Externí odkaz:
https://doaj.org/article/89c4e6c3d6834889a60603820d02bb9b
Autor:
Blanca Martin-Burgos, Wanqi Wang, Ivana William, Selma Tir, Innus Mohammad, Reja Javed, Stormi Smith, Yilin Cui, Jessica Arzavala, Dalilah Mora, Ciearra B. Smith, Vincent van der Vinne, Penny C. Molyneux, Stephen C. Miller, David R. Weaver, Tanya L. Leise, Mary E. Harrington
Publikováno v:
J Biol Rhythms
Circadian rhythms are driven by daily oscillations of gene expression. An important tool for studying cellular and tissue circadian rhythms is the use of a gene reporter, such as bioluminescence from the reporter gene luciferase controlled by a rhyth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d541c72fc7e8db7a9f48313c00b1e96
https://europepmc.org/articles/PMC9282071/
https://europepmc.org/articles/PMC9282071/
Autor:
Jiawei Wang, Mursal Nader, Can Cui, Martina Damo, Achia Khatun, Ivana William, Julie F. Cheung, Nikhil S. Joshi, Eric Fagerberg, Smita Krishnaswamy, Amanda Hutchins, Gena G. Foster, Weiguo Cui, Isabel Monroy, Moujtaba Y. Kasmani, Aarthi Venkat, Brittany Fitzgerald, Hongyu Zhao, Manik Kuchroo, Kelli A. Connolly, Noah I. Hornick, Dylan L. Mariuzza
Publikováno v:
Science Immunology. 6
Tumor-specific CD8 + T cells in stable tumor-draining lymph node reservoir are clonally and developmentally related to those in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41f715a2520f1cb44ad2833c27cb0906
https://doi.org/10.1126/sciimmunol.abg7836
https://doi.org/10.1126/sciimmunol.abg7836
Autor:
Gena G. Foster, Ivana William, Julie F. Cheung, Brittany Fitzgerald, Nikhil S. Joshi, Can Cui, Kelli A. Connolly, Eric Fagerberg, Noah I. Hornick, Dylan L. Mariuzza
Publikováno v:
Cell reports methods
SUMMARY Kras-driven lung adenocarcinoma (LUAD) is the most common lung cancer. A significant fraction of patients with Kras-driven LUAD respond to immunotherapy, but mechanistic studies of immune responses against LUAD have been limited because of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388e697d2e0be1e21fb9e170b3ed3897
https://pubmed.ncbi.nlm.nih.gov/34632444
https://pubmed.ncbi.nlm.nih.gov/34632444
Autor:
Kelli A, Connolly, Manik, Kuchroo, Aarthi, Venkat, Achia, Khatun, Jiawei, Wang, Ivana, William, Noah I, Hornick, Brittany L, Fitzgerald, Martina, Damo, Moujtaba Y, Kasmani, Can, Cui, Eric, Fagerberg, Isabel, Monroy, Amanda, Hutchins, Julie F, Cheung, Gena G, Foster, Dylan L, Mariuzza, Mursal, Nader, Hongyu, Zhao, Weiguo, Cui, Smita, Krishnaswamy, Nikhil S, Joshi
Publikováno v:
Sci Immunol
“Stem-like” TCF1(+) CD8(+) T cells (T(SL)) are necessary for long-term maintenance of T cell responses and the efficacy of immunotherapy but, as tumors contain signals that should drive T-cell terminal-differentiation, how these cells are maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e6e92f53c1eaaa1f1c6306e7c6ecb7b
https://pubmed.ncbi.nlm.nih.gov/34597124
https://pubmed.ncbi.nlm.nih.gov/34597124
Autor:
Julie F. Cheung, Eric Fagerberg, Gena G. Foster, Noah I. Hornick, Dylan L. Mariuzza, Aarthi Venkat, Kelli A. Connolly, Ivana William, Amanda Hutchins, Weiguo Cui, Manik Kuchroo, Isabel Monroy, Jiawei Wang, Martina Damo, Achia Khatun, Moujtaba Y. Kasmani, Nikhil S. Joshi, Smita Krishnaswamy, Brittany Fitzgerald, Hongyu Zhao, Can Cui
“Stem-like” TCF1+CD8+T cells (TSL) are necessary for long-term maintenance of T cell responses and the efficacy of immunotherapy but, as tumors contain signals that should drive T-cell terminal-differentiation, how these cells are maintained in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a92da2441d764fae88781e256299859c
https://doi.org/10.1101/2021.01.27.428467
https://doi.org/10.1101/2021.01.27.428467
Autor:
Darwin Kwok, William Damsky, Kathryn Clulo, Can Cui, Martina Damo, Ivana William, Jonathan S. Leventhal, Noah I. Hornick, Nikhil S. Joshi
Publikováno v:
SSRN Electronic Journal.
SummaryPeripheral tolerance is thought to result from anergy or deletion of self-reactive T cells shortly after antigen encounter. However, the frequent occurrences of immune-related Adverse Events (irAEs) following checkpoint inhibitor (CPI) treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528d442e1d071299b2e358257f1502d7
https://doi.org/10.2139/ssrn.3883633
https://doi.org/10.2139/ssrn.3883633
Autor:
Noah I. Hornick, Dylan L. Mariuzza, Brittany Fitzgerald, Gena G. Foster, Can Cui, Kelli A. Connolly, Ivana William, Julie F. Cheung, Nikhil S. Joshi, Eric Fagerberg
Publikováno v:
SSRN Electronic Journal.
Kras-driven lung adenocarcinoma (LUAD) is one of the most common forms of lung cancer. A significant fraction of patients with Kras-driven LUAD respond to immunotherapy, but mechanistic studies of immune responses against LUAD have been limited becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::760e23e6aa83e9dd4bd4c141cfe8db87
https://doi.org/10.2139/ssrn.3835424
https://doi.org/10.2139/ssrn.3835424
Autor:
Elliot H. Akama-Garren, Da-Yae Lee, Vasilena Gocheva, Leah Marie Schmidt, Brittany Fitzgerald, Alice Boileve, Can Cui, Nikhil S. Joshi, Julie Cheung, Martina Damo, Gena G. Foster, Isabel Monroy, Peter Cabeceiras, Yisi Lu, Prashanth Gokare, Josephine H. Wilson, Kelli A. Connolly, Tyler Jacks, Mursal Nader, Ivana William, Greg P. Chang
Mouse models with inducible neoantigens have been historically difficult to generate because of leaky expression of antigens in the thymus, which causes central tolerance in developing CD8 and CD4 T cells. Attempts to resolve this problem using exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8a12dd9cc0c0c518a51a2d27e37af0
https://doi.org/10.1101/2020.01.09.900894
https://doi.org/10.1101/2020.01.09.900894