Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ivan Zahradnik"'
Autor:
Alexandra Zahradnikova Jr, Simona Kazmerova, Marta Novotova, Ivan Zahradnik, Alexandra Zahradnikova
Publikováno v:
Biophysical Journal. 118:407a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a1a237b7c356006cd2718584c08c251
https://doi.org/10.1016/j.bpj.2019.11.2306
https://doi.org/10.1016/j.bpj.2019.11.2306
Publikováno v:
Biophysical Journal. 110(3):261a-262a
In failing myocytes, impaired E-C coupling is often associated with loss of t-tubules and appearance of orphaned calcium release units. Impairment of communication between Ca-channels of sarcolemma and of sarcoplasmic reticulum (SR) has been observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71702bd554285aa688574155cfed2e8d
Autor:
Ivan Zahradnik, Mireille Giner, Michel Langlois, Sames Sicsic, Isabelle Berque-Bestel, Jeanne Mialet, Jean-Louis Soulier, Rodolphe Fischmeister, Frank Lezoualc'h, Sophie Curtet, Patrick Donzeau-Gouge
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2000, 43 (20), pp.3761-3769. ⟨10.1021/jm0009538⟩
Journal of Medicinal Chemistry, 2000, 43 (20), pp.3761-3769. ⟨10.1021/jm0009538⟩
International audience; New derivatives of arylpiperazine 9 were designed from ML 10302, a potent 5-HT 4 receptor agonist in the gastrointestinal system. Compounds were synthesized by condensation of a number of available arylpiperazines or heteroary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e623e3fa2d26bb562759e326bd87db
https://doi.org/10.1021/jm0009538
https://doi.org/10.1021/jm0009538
Publikováno v:
Biophysical Journal. 110:587a
During development, cardiac myocytes undergo rapid growth and structural remodeling. With increased cell size and increased requirements for calcium for contraction, excitation-contraction coupling becomes increasingly dependent on calcium-induced ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0362cbe0a5aef0d1b54ab8ee71cd5cfc
https://doi.org/10.1016/j.bpj.2015.11.3135
https://doi.org/10.1016/j.bpj.2015.11.3135
Publikováno v:
Biophysical Journal. 102(3)
Calcium signaling during cardiac excitation-contraction coupling is compromised after myocardial injury (MI). Myocytes of injured myocardium display reduced synchronization of calcium spikes at low calcium current density indicating worsened communic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e52b950c44d0001d1a93135ffc28d1
Publikováno v:
The Journal of General Physiology
We have used whole-cell and perforated patches to study ionic currents induced by hypotonic extracellular solutions (HTS, 185 mOsm instead of 290 mOsm) in endothelial cells from human umbilical veins. These currents activated within 30-50 s after app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e195625281314d82432a0a2bbeac2c0
http://europepmc.org/articles/PMC2219214
http://europepmc.org/articles/PMC2219214
Publikováno v:
Endocrine regulations. 39(2)
The aim of the present study was to characterise and compare alterations in the ultrastructure of the functionally identified isolated twitch skeletal muscle fibres of the frog after repeated tetanic stimulation and under experimental conditions whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40ba52263303859b6de187a4345179f3
https://pubmed.ncbi.nlm.nih.gov/16229154
https://pubmed.ncbi.nlm.nih.gov/16229154
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Ryanodine receptor channels at calcium release sites of cardiac myocytes operate on the principle of calcium-induced calcium release. In vitro experiments revealed competition of Ca2+ and Mg2+ in the activation of ryanodine receptors (RyRs) as well a
Externí odkaz:
https://doaj.org/article/ee4e7a86450b41e4bcf99af0bf52605d
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1535 (2022)
The coronavirus transforms the cytoplasm of susceptible cells to support virus replication. It also activates autophagy-like processes, the role of which is not well understood. Here, we studied SARS-CoV-2-infected Vero E6 cells using transmission el
Externí odkaz:
https://doaj.org/article/b26d04f451af426b8ebb431c9fd7c609
Publikováno v:
Biophysical Journal. 102:316a
Local character of calcium release in cardiac myocytes implies independent recruitment of calcium release units by triggering stimuli. Calcium release from individual CRUs also displays quantal character, interpreted either as recruitment of small co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaf4f9c7a06eeef7ff7cc46eeb7e721
https://doi.org/10.1016/j.bpj.2011.11.1739
https://doi.org/10.1016/j.bpj.2011.11.1739