Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ivan Yudushkin"'
Autor:
Ivan Yudushkin
Publikováno v:
Biomolecules, Vol 9, Iss 2, p 67 (2019)
Intracellular signaling pathways mediate the rapid response of cells to environmental cues. To control the fidelity of these responses, cells coordinate the activities of signaling enzymes with the strength, timing, and localization of the upstream s
Externí odkaz:
https://doaj.org/article/9372de4dffa046ac8090e0c0cc517751
Autor:
Ivan, Yudushkin
Publikováno v:
The Journal of Cell Biology
A sensitive new genetically encoded lipid biosensor for PI(3,4)P2 has been developed, revealing the lipid is mainly produced via PIP3 after activation of class I PI3K signaling. The PI(3,4)P2 is also a direct substrate for the tumor suppressor lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::371e533abd89d96c1c8521a182a2876c
https://pubmed.ncbi.nlm.nih.gov/30591513
https://pubmed.ncbi.nlm.nih.gov/30591513
Publikováno v:
Molecular cell. 65(3)
Protein kinase B/Akt regulates cellular metabolism, survival, and proliferation in response to hormones and growth factors. Hyperactivation of Akt is frequently observed in cancer, while Akt inactivation is associated with severe diabetes. Here, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::210accf20e82cd8e22eec1d326d3bd24
https://pubmed.ncbi.nlm.nih.gov/28157504
https://pubmed.ncbi.nlm.nih.gov/28157504
Autor:
Ivan Yudushkin, Ronald D. Vale
Publikováno v:
Proceedings of the National Academy of Sciences. 107:22128-22133
Phosphorylation of the T-cell receptor complex (TcR/CD3) mediates the survival and antigen-induced activation of T cells. TcR/CD3 phosphorylation is usually monitored using phospho-specific antibodies, which precludes dynamic measurements. Here, we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4d8ad5e42117c8626aa8743479c063
https://doi.org/10.1073/pnas.1016388108
https://doi.org/10.1073/pnas.1016388108
Autor:
M. Yu. Bobrov, Vladimir V. Bezuglov, Natalia Gretskaya, N. F. Myasoedov, Ivan Yudushkin, V. P. Shevchenko, I. Yu. Nagaev
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 46:187-193
Tritium labelled arachidonic acid amides with dopamine, serotonin, vanillyl-amine and the ethyleneglycol ester moieties with high specific activity (120 Ci/mmol) and yield (70–90%) were prepared from tritiated arachidonic acid by condensation with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd0c1e0455cbf262e991c883f64cb5d1
https://doi.org/10.1002/jlcr.663
https://doi.org/10.1002/jlcr.663
Publikováno v:
Molecular Cell. 65:416-431.e6
Protein kinase B/Akt regulates cellular metabolism, survival, and proliferation in response to hormones and growth factors. Hyperactivation of Akt is frequently observed in cancer, while Akt inactivation is associated with severe diabetes. Here, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3380a2ddf2c5313629485024c6670bc
https://doi.org/10.1016/j.molcel.2016.12.028
https://doi.org/10.1016/j.molcel.2016.12.028
Autor:
Ivan Yudushkin, Benjamin G. Neel, Philippe I. H. Bastiaens, Carsten Schultz, Andreas Schleifenbaum, A. Kinkhabwala
Publikováno v:
Science (New York, N.Y.). 315(5808)
Endoplasmic reticulum–localized protein-tyrosine phosphatase PTP1B terminates growth factor signal transduction by dephosphorylation of receptor tyrosine kinases (RTKs). But how PTP1B allows for RTK signaling in the cytoplasm is unclear. In order t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8007dc362870818751c206956c04b2c3
https://pubmed.ncbi.nlm.nih.gov/17204654
https://pubmed.ncbi.nlm.nih.gov/17204654