Výsledky vyhledávání - "Ivan Yu. Golushko"

Hidden symmetry of the flavivirus protein shell and pH-controlled reconstruction of the viral surface

Autor: Olga V. Konevtsova, Ivan Yu. Golushko, Rudolf Podgornik, Sergei B. Rochal

Publikováno v: Biomaterials Science. 11:225-234

Using recent Zika virus structural data we reveal a hidden symmetry of protein order in immature and mature flavivirus shells, violating the Caspar-Klug paradigmatic model of capsid structures. We show that proteins of the outer immature shell layer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b3de2ccb1102be0d66bd8f6fc1b9e3
https://doi.org/10.1039/d2bm01562e

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Packing and trimer-to-dimer protein reconstruction in icosahedral viral shells with a single type of symmetrical structural unit

Autor: Sergei B. Rochal, Olga V. Konevtsova, Daria S. Roshal, Anže Božič, Ivan Yu. Golushko, Rudolf Podgornik

Publikováno v: Nanoscale advances. 4(21)

Understanding the principles of protein packing and the mechanisms driving morphological transformations in virus shells (capsids) during their maturation can be pivotal for the development of new antiviral strategies. Here, we study how these princi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62ea73f95a6f9acd39a7f927bde3dca
https://pubmed.ncbi.nlm.nih.gov/36341291

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