Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ivan W. F. Davidson"'
Autor:
Robert P. Beliles, Ivan W. F. Davidson
Publikováno v:
Drug Metabolism Reviews. 23:493-599
Trichloroethylene (TRI) is readily absorbed into the body through the lungs and gastrointestinal mucosa. Exposure to TRI can occur from contamination of air, water, and food; and this contamination may be sufficient to produce adverse effects in the
Publikováno v:
European Journal of Pharmacology. 31:29-37
Previous studies in man have shown pentaerythritol (PE) trinitrate, given either sublingually or orally, produces a prolonged hypotensive effect. The coronary vasodilator and systemic vasodepressor activities of PE trinitrate and its metabolites, PE
Autor:
W. L. Blackwell, Ivan W. F. Davidson
Publikováno v:
Experimental Biology and Medicine. 127:66-70
SummaryAdult squirrel monkeys maintained on a commercial chow demonstrated an impaired carbohydrate metabolism as evaluated by diagnostic tolbutamide and glucose tolerance tests. The possibility that the diet was deficient in trivalent chromium was i
Autor:
Richard L. Burt, Ivan W. F. Davidson
Publikováno v:
American Journal of Obstetrics and Gynecology. 116:601-608
Plasma chromium (Cr) concentrations were determined for healthy nonpregnant women and also for women in late pregnancy of similar ages. Plasma Cr was found to be significantly lower in the fasting fireanant subjects (2.97 ± 0.11 standard error of th
Publikováno v:
Experimental Biology and Medicine. 120:797-802
SummaryThe addition of nicotinamide adenylate compounds was found to maintain, to a significant extent, the glycolytic capacity of fresh human erythrocytes incubated in vitro for 20 hours. The compounds appeared to act also to restore the metabolism
Autor:
Richard L. Burt, Ivan W. F. Davidson
Publikováno v:
Acta Diabetologica Latina. 10:770-778
Normal human pregnancy is characterized by substantial changes in peripheral glucose utilization as well as homeostatic alterations in insulin release and response mechanisms. Recent observations we have made indicate a relative deficiency in plasma
Publikováno v:
Journal of Pharmaceutical Sciences. 60:274-277
The absorption, biotransformation, and excretion of pentaerythritol tetranitrate was studied after oral administration of two dosages, 20 and 40 mg., to patients. The drug was given as 14C-pentaerythritol tetranitrate incorporated into tablets of a t
Autor:
Jean C. Parker, Ivan W. F. Davidson
Publikováno v:
Drug metabolism reviews. 4(1)
(1975). Organic Nitrates in Perspective. Drug Metabolism Reviews: Vol. 4, No. 1, pp. 135-138.
Publikováno v:
Clinical pharmacology and therapeutics. 22(6)
The metabolism of l-bunolol, a new beta-blocking drug, was studied in man after single oral 3-mg doses of 3H-labeled compound. Absorption from the gut was rapid and virtually complete. Peak levels of bunolol and of dihydrobunolol, an active metabolit
Autor:
Ivan W. F. Davidson, Robert W. Watkins
Publikováno v:
European journal of pharmacology. 62(2-3)
Nitroprusside shares many of the pharmacological actions of nitroglycerin. We investigated the characteristics of the relaxant action of these two vasodilators on vascular smooth muscle. Both drugs completely reduced, in a dose-related fashion, the m