Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ivan V. Chernykh"'
Autor:
Aleksey V. Shchulkin, Pelageya D. Erokhina, Anna V. Goncharenko, Pavel Yu. Mylnikov, Ivan V. Chernykh, Yulia V. Abalenikhina, Maria S. Kotliarova, Elena N. Yakusheva
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1529 (2023)
2-Ethyl-6-methyl-3-hydroxypyridine succinate (EMHPS, Mexidol) is an original antioxidant and an anti-ischemic drug with the possibility of wide applications in the complex therapy of diseases, accompanied by the development of oxidative stress and is
Externí odkaz:
https://doaj.org/article/27e3a63a4f6246beacacfaa4b9efeea0
Autor:
Ivan V. Chernykh, Aleksey V. Shchulkin, Sergei K. Pravkin, Maria V. Gatsanoga, Elena N. Yakusheva
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 15, Iss 1, Pp 65-70 (2021)
Introduction. Despite the development of numerous drugs with neuroprotective activity, their efficacy in cerebrovascular disease remains low, which may partly be due to the efflux function of protein ABCB1 and insufficient penetration of the blood-br
Externí odkaz:
https://doaj.org/article/ab63bab3719e4a42ba93af3d72c684bf
Autor:
Ivan V. Chernykh, Alexey V. Shchulkin, Pavel Yu. Mylnikov, Ekaterina E. Kirichenko, Maria V. Gatsanoga, Elena N. Yakusheva
Publikováno v:
Annals of Clinical and Experimental Neurology. 16:47-52
Introduction. Increased functional activity of the P-glycoprotein transporter (ABCB1) in the blood-brain barrier (BBB) is a possible reason why neuroprotective pharmacotherapy is ineffective after ischaemic stroke. Study aim to develop a way to inhib
Autor:
Ivan V. Chernykh, Ekarina E. Kirichenko, Aleksey V. Shchulkin, Natalia M. Popova, Anna A. Kotlyarova
Publikováno v:
I.P. Pavlov Russian Medical Biological Herald. 26:305-316
Inhibition of Pglycoprotein transporter protein (ABCB1protein, Pgp) is a promising method to increase the effectiveness of pharmacotherapy in different pathologies: neoplastic diseases, epilepsy, cerebral circulation disorders. Pgp is a large transme