Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ivan V Zvyagin"'
Autor:
Artem Mikelov, Evgeniia I Alekseeva, Ekaterina A Komech, Dmitry B Staroverov, Maria A Turchaninova, Mikhail Shugay, Dmitriy M Chudakov, Georgii A Bazykin, Ivan V Zvyagin
Publikováno v:
eLife, Vol 11 (2022)
The stability and plasticity of B cell-mediated immune memory ensures the ability to respond to the repeated challenges. We have analyzed the longitudinal dynamics of immunoglobulin heavy chain repertoires from memory B cells, plasmablasts, and plasm
Externí odkaz:
https://doaj.org/article/abfef42b83a945a8a9be7f4644f92e8d
Autor:
Mikhail Shugay, Dmitriy V Bagaev, Maria A Turchaninova, Dmitriy A Bolotin, Olga V Britanova, Ekaterina V Putintseva, Mikhail V Pogorelyy, Vadim I Nazarov, Ivan V Zvyagin, Vitalina I Kirgizova, Kirill I Kirgizov, Elena V Skorobogatova, Dmitriy M Chudakov
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 11, p e1004503 (2015)
Despite the growing number of immune repertoire sequencing studies, the field still lacks software for analysis and comprehension of this high-dimensional data. Here we report VDJtools, a complementary software suite that solves a wide range of T cel
Externí odkaz:
https://doaj.org/article/450c0b60a1b045c1b9cda00e1a45601a
Autor:
Ilgar Z Mamedov, Olga V Britanova, Ivan V Zvyagin, Maria A Turchaninova, Dmitriy A Bolotin, Ekaterina V Putintseva, Yuriy B Lebedev, Dmitriy M Chudakov
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
High-throughput sequencing has the power to reveal the nature of adaptive immunity as represented by the full complexity of T cell receptor (TCR) and antibody (IG) repertoires, but is at present severely compromised by the quantitative bias, bottlene
Externí odkaz:
https://doaj.org/article/27992835311d4d9fb9b1fbf2f8374c66
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
An individual’s T-cell repertoire constantly changes under the influence of external and internal factors. Cells that do not receive a stimulatory signal die, while those that encounter and recognize a pathogen or receive a co-stimulatory signal di
Externí odkaz:
https://doaj.org/article/af5032eadcf744bdb530be0a40851f29
Autor:
Saveliy A. Sheetikov, Alexandra A. Khmelevskaya, Ksenia V. Zornikova, Ivan V. Zvyagin, Alina S. Shomuradova, Yana V. Serdyuk, Naina T. Shakirova, Iuliia O. Peshkova, Aleksei Titov, Dmitrii S. Romaniuk, Irina A. Shagina, Dmitry M. Chudakov, Dmitry O. Kiryukhin, Olga V. Shcherbakova, Ekaterina G. Khamaganova, Vitalina Dzutseva, Andrei Afanasiev, Apollinariya V. Bogolyubova, Grigory A. Efimov
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Adenovirus vaccines, particularly the COVID-19 Ad5-nCoV adenovirus vaccine, have emerged as promising tools in the fight against infectious diseases. In this study, we investigated the structure of the T cell response to the Spike protein of the SARS
Externí odkaz:
https://doaj.org/article/c8dda62480a240ed83d72a7ba8d1b3ca
Autor:
Dmitrii S. Shcherbinin, Vadim K. Karnaukhov, Ivan V. Zvyagin, Dmitriy M. Chudakov, Mikhail Shugay
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionT-cell receptor (TCR) recognition of foreign peptides presented by the major histocompatibility complex (MHC) initiates the adaptive immune response against pathogens. While a large number of TCR sequences specific to different antigenic
Externí odkaz:
https://doaj.org/article/049b3dfacefa45d383e8fc31bcba2959
Autor:
Xinbo Yang, Lee I. Garner, Ivan V. Zvyagin, Michael A. Paley, Ekaterina A. Komech, Kevin M. Jude, Xiang Zhao, Ricardo A. Fernandes, Lynn M. Hassman, Grace L. Paley, Christina S. Savvides, Simon Brackenridge, Max N. Quastel, Dmitriy M. Chudakov, Paul Bowness, Wayne M. Yokoyama, Andrew J. McMichael, Geraldine M. Gillespie, K. Christopher Garcia
Publikováno v:
Nature. 612:771-777
Human leucocyte antigen B*27 (HLA-B*27) is strongly associated with inflammatory diseases of the spine and pelvis (for example, ankylosing spondylitis (AS)) and the eye (that is, acute anterior uveitis (AAU))1. How HLA-B*27 facilitates disease remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80271848c224b3e07eeca9c4183c0f0d
https://doi.org/10.1038/s41586-022-05501-7
https://doi.org/10.1038/s41586-022-05501-7
Autor:
Ekaterina A. Komech, Anastasia D. Koltakova, Anna A. Barinova, Anastasia A. Minervina, Maria A. Salnikova, Evgenia I. Shmidt, Tatiana V. Korotaeva, Elena Y. Loginova, Shandor F. Erdes, Ekaterina A. Bogdanova, Mikhail Shugay, Sergey Lukyanov, Yury B. Lebedev, Ivan V. Zvyagin
Publikováno v:
Frontiers in Immunology. 13
Spondyloarthritis (SpA) comprises a number of inflammatory rheumatic diseases with overlapping clinical manifestations. Strong association with several HLA-I alleles and T cell infiltration into an inflamed joint suggest involvement of T cells in SpA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb39a3d75e9d9558da5b4c1b54608c6e
https://doi.org/10.3389/fimmu.2022.973243
https://doi.org/10.3389/fimmu.2022.973243
Autor:
Vadim Karnaukhov, Wayne Paes, Isaac B. Woodhouse, Thomas Partridge, Annalisa Nicastri, Simon Brackenridge, Dmitrii Shcherbinin, Dmitry M. Chudakov, Ivan V. Zvyagin, Nicola Ternette, Hashem Koohy, Persephone Borrow, Mikhail Shugay
Publikováno v:
Frontiers in immunology. 13
Human leukocyte antigen (HLA) genes are the most polymorphic loci in the human genome and code for proteins that play a key role in guiding adaptive immune responses by presenting foreign and self peptides (ligands) to T cells. Each person carries up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26c08e09ef1ac6f43ad5c05172373f3
https://pubmed.ncbi.nlm.nih.gov/36605212
https://pubmed.ncbi.nlm.nih.gov/36605212
Autor:
Evgeniia I Alekseeva, Artem Mikelov, Ekaterina A Komech, Dmitry B Staroverov, Maria A Turchaninova, Mikhail Shugay, Dmitriy M Chudakov, Georgii A Bazykin, Ivan V Zvyagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf5c3d38cbea1d9dd78e16c1ee608e35
https://doi.org/10.7554/elife.79254.sa2
https://doi.org/10.7554/elife.79254.sa2
