Výsledky vyhledávání - "Ivan V, Semenyuta"

Akademický článek

Theoretical and Experimental Studies of Phosphonium Ionic Liquids as Potential Antibacterials of MDR Acinetobacter baumannii

Autor: Larysa O. Metelytsia, Diana M. Hodyna, Ivan V. Semenyuta, Vasyl V. Kovalishyn, Sergiy P. Rogalsky, Kateryna Yu Derevianko, Volodymyr S. Brovarets, Igor V. Tetko

Publikováno v: Antibiotics, Vol 11, Iss 4, p 491 (2022)

A previously developed model to predict antibacterial activity of ionic liquids against a resistant A. baumannii strain was used to assess activity of phosphonium ionic liquids. Their antioxidant potential was additionally evaluated with newly develo

Externí odkaz: https://doaj.org/article/4d083075b2f14074aee1cc0dcc6bca4f

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Akademický článek

In silico study of 4-phosphorylated derivatives of 1,3-oxazole as inhibitors of Candida albicans fructose-1,6-bisphosphate aldolase II

Autor: Ivan V. Semenyuta, Oleksandr L. Kobzar, Diana M. Hodyna, Volodymyr S. Brovarets, Larysa O. Metelytsia

Publikováno v: Heliyon, Vol 5, Iss 4, Pp e01462- (2019)

In this study, the synthesis, in vitro anti-Candida activity and molecular modeling of 4-phosphorylated derivatives of 1,3-oxazole as inhibitors of Candida albicans fructose-1,6-bisphosphate aldolase (FBA-II) are demonstrated and discussed. Significa

Externí odkaz: https://doaj.org/article/a14d5559cd49475c9aa4a1f4889b6a40

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Synthesis, QSAR modeling, and molecular docking of novel fused 7‐deazaxanthine derivatives as adenosine A 2A receptor antagonists

Autor: Svitlana V. Shishkina, I. O. Yaremchuk, Vasyl Kovalishyn, Anna M. Zinchenko, Ivan V. Semenyuta, Diana Hodyna, L. V. Muzychka, Oleg B. Smolii, Larysa Metelytsia, Evgenii V. Verves

Publikováno v: Chemical Biology & Drug Design. 100:1025-1032

Predictive QSAR models for the search of new adenosine A2A receptor antagonists were developed by using OCHEM platform. The predictive ability of the regression models has coefficient of determination q2 = 0.65-0.71 with cross-validation and independ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71c7a320fedcf740fbd9c89ff7f82995
https://doi.org/10.1111/cbdd.13975

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In vitro and in silico study of 1,3-oxazol-4-yltriphenylphosphonium salts as potential inhibitors of Candida albicans transglycosylase

Autor: Ivan V. Semenyuta, Maryna V. Kachaeva, Larysa Metelytsia, Diana Hodyna, Maria M. Trush, Volodymyr Brovarets

Publikováno v: Ukr. Bioorg. Acta 2021, Vol. 16, N1. 16:25-33

The previously established in vitro high antimicrobial potential of triphenylphosphonium salts (TPPs) against bacterial (Staphylococcus aureus ATCC 25923 and multi-drug resistant (MDR)) and fungal (Candida albicans ATCC 10231 and MDR) strains made it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52bcd25f0bf14e87ee728559f57ed29a
https://doi.org/10.15407/bioorganica2021.01.025

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In silico and in vitro Studies of Imidazolium Ionic Liquids as Effective Antibacterial Agents against Multidrug Resistant Escherichia coli Strains

Autor: Sergiy Rogalsky, Volodymyr Blagodatny, Ivan V. Semenyuta, Larysa Metelytsia, Vasyl Kovalishyn, Diana Hodyna

Publikováno v: Current Bioactive Compounds. 17:130-144

Background: Escherichia coli especially its multiresistant strains as the common foodborne pathogens cause bloodstream infections, nosocomial pneumonia, infections of the skin and soft tissues. Therefore, the search for new effective biologically act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e858031df732de7934be0860957c0db8
https://doi.org/10.2174/1573407216999200422115655

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Ionic Liquids with Anti-Candida and Anticancer Dual Activity as Potential N-Myristoyltransferase Inhibitors

Autor: Sergiy Rogalsky, Oleksandr L. Kobzar, Volodymyr Blagodatny, Larisa Kalashnikova, Diana Hodyna, Ivan V. Semenyuta, Maria M. Trush, Larysa Metelytsia

Publikováno v: Current Bioactive Compounds. 16:1036-1041

Background: Currently, a study on the relationship between candidiasis and cancer has been conducted. Until recent years, the opportunistic fungus C. albicans is mainly associated with cancer processes and is able to stimulate carcinogenesis and meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3be58273d42555ee3aa7b1b489f2afae
https://doi.org/10.2174/1573407215666191007120402

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Functionalized imidazolium-based ionic liquids: biological activity evaluation, toxicity screening, spectroscopic, and molecular docking studies

Autor: Alla D. Ocheretniuk, Larisa Kalashnikova, Ivan V. Semenyuta, Larisa O. Metelytsia, Sergiy Rogalsky, Maria M. Trush, Volodymyr Blagodatnyi, Oleksandr L. Kobzar, Diana Hodyna, Sergey I. Vdovenko

Publikováno v: Medicinal Chemistry Research. 29:2181-2191

A series of long-chain imidazolium-based ionic liquids (ILs) 1-dodecyl-3-methylimidazolium chloride (1), 1,3-bis(octyloxycarbonylmethyl)imidazolium chloride (2) and 1-dodecyloxycarbonylmethyl-3-methyloxycarbonylmethylimidazolium chloride (3), were sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cce2b2f971e1cf74d748f7cc90d9450a
https://doi.org/10.1007/s00044-020-02631-3

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Hybrid Design of Isonicotinic Acid Hydrazide Derivatives: Machine Learning Studies, Synthesis and Biological Evaluation of their Antituberculosis Activity

Autor: Larysa Metelytsia, Volodymyr Brovarets, Volodymyr Blagodatny, V. O. Sinenko, Ivan V. Semenyuta, Gennady Poda, S. R. Slivchuk, Diana Hodyna, Vasyl Kovalishyn

Publikováno v: Current Drug Discovery Technologies. 17:365-375

Background: Tuberculosis (TB) is an infection disease caused by Mycobacterium tuberculosis (Mtb) bacteria. One of the main causes of mortality from TB is the problem of Mtb resistance to known drugs. Objective: The goal of this work is to identify po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ca54fa40aa40730a0b254037ada067
https://doi.org/10.2174/1570163816666190411110331

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eDNA Inactivation and Biofilm Inhibition by the Polymeric Biocide Polyhexamethylene Guanidine Hydrochloride (PHMG-Cl)

Autor: Geert Potters, Larysa Metelytsia, Olga Iungin, Ivan V. Semenyuta, Sergiy Rogalsky, Andrew J. Spiers, Oksana Tarasyuk, Ianina Pokholenko, Nadiia P. Kysil, Svitlana Y. Rymar, Viktoria V Potochilova, Kateryna L. Rudnieva, Taras P. Baranovskyi, Olena Moshynets

The choice of effective biocides used for routine hospital practice should consider the role of disinfectants in the maintenance and development of local resistome and how they might affect antibiotic resistance gene transfer within the hospital micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1b432e039013868d1862c070987ffe

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eDNA Inactivation and Biofilm Inhibition by the PolymericBiocide Polyhexamethylene Guanidine Hydrochloride (PHMG-Cl)

Autor: Olena V. Moshynets, Taras P. Baranovskyi, Olga S. Iungin, Nadiia P. Kysil, Larysa O. Metelytsia, Ianina Pokholenko, Viktoria V. Potochilova, Geert Potters, Kateryna L. Rudnieva, Svitlana Y. Rymar, Ivan V. Semenyuta, Andrew J. Spiers, Oksana P. Tarasyuk, Sergiy P. Rogalsky

Publikováno v: International Journal of Molecular Sciences
International journal of molecular sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 731
International Journal of Molecular Sciences, Vol 23, Iss 731, p 731 (2022)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261811f49affe34d383b0db5518f1903
https://pubmed.ncbi.nlm.nih.gov/35054915

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