Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Ivan V, Kulakovskiy"'
Autor:
Matvei Khoroshkin, Andrey Buyan, Martin Dodel, Albertas Navickas, Johnny Yu, Fathima Trejo, Anthony Doty, Rithvik Baratam, Shaopu Zhou, Sean B. Lee, Tanvi Joshi, Kristle Garcia, Benedict Choi, Sohit Miglani, Vishvak Subramanyam, Hailey Modi, Christopher Carpenter, Daniel Markett, M. Ryan Corces, Faraz K. Mardakheh, Ivan V. Kulakovskiy, Hani Goodarzi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract In our cells, a limited number of RNA binding proteins (RBPs) are responsible for all aspects of RNA metabolism across the entire transcriptome. To accomplish this, RBPs form regulatory units that act on specific target regulons. However, th
Externí odkaz:
https://doaj.org/article/e0a9c0d9b7a0471c8ee72df7e5f560df
Autor:
Saumya Agrawal, Andrey Buyan, Jessica Severin, Masaru Koido, Tanvir Alam, Imad Abugessaisa, Howard Y Chang, Josée Dostie, Masayoshi Itoh, Juha Kere, Naoto Kondo, Yunjing Li, Vsevolod J Makeev, Mickaël Mendez, Yasushi Okazaki, Jordan A Ramilowski, Andrey I Sigorskikh, Lisa J Strug, Ken Yagi, Kayoko Yasuzawa, Chi Wai Yip, Chung Chau Hon, Michael M Hoffman, Chikashi Terao, Ivan V Kulakovskiy, Takeya Kasukawa, Jay W Shin, Piero Carninci, Michiel J L de Hoon
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0295971 (2024)
The human genome is pervasively transcribed and produces a wide variety of long non-coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types. Some specific nuclear lncRNAs have been shown to be important regulatory comp
Externí odkaz:
https://doaj.org/article/cd55b6045f20467eb83991410871c30d
Autor:
Irina A. Eliseeva, Andrey I. Buyan, Egor A. Smolin, Karina S. Kaliadzenka, Sergey Popov, Ivan V. Kulakovskiy, Dmitry N. Lyabin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1736 (2024)
Y-box-binding proteins (YB proteins) are multifunctional DNA- and RNA-binding proteins that play an important role in the regulation of gene expression. The high homology of their cold shock domains and the similarity between their long, unstructured
Externí odkaz:
https://doaj.org/article/2d0771e67f0a45bdaf1231c56698ae9c
Autor:
Aksinya N. Uvarova, Ekaterina M. Stasevich, Alina S. Ustiugova, Nikita A. Mitkin, Elina A. Zheremyan, Savely A. Sheetikov, Ksenia V. Zornikova, Apollinariya V. Bogolyubova, Mikhail A. Rubtsov, Ivan V. Kulakovskiy, Dmitry V. Kuprash, Kirill V. Korneev, Anton M. Schwartz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13790 (2023)
Single-nucleotide polymorphism rs71327024 located in the human 3p21.31 locus has been associated with an elevated risk of hospitalization upon SARS-CoV-2 infection. The 3p21.31 locus contains several genes encoding chemokine receptors potentially rel
Externí odkaz:
https://doaj.org/article/e24f6e1c27614680b34a6dea7a157abf
Autor:
Aleksandra S. Anisimova, Natalia M. Kolyupanova, Nadezhda E. Makarova, Artyom A. Egorov, Ivan V. Kulakovskiy, Sergey E. Dmitriev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8361 (2023)
While protein synthesis is vital for the majority of cell types of the human body, diversely differentiated cells require specific translation regulation. This suggests the specialization of translation machinery across tissues and organs. Using tran
Externí odkaz:
https://doaj.org/article/930fa60001e84ce5b96d851b0675ced9
Autor:
Sergey Abramov, Alexandr Boytsov, Daria Bykova, Dmitry D. Penzar, Ivan Yevshin, Semyon K. Kolmykov, Marina V. Fridman, Alexander V. Favorov, Ilya E. Vorontsov, Eugene Baulin, Fedor Kolpakov, Vsevolod J. Makeev, Ivan V. Kulakovskiy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Single-nucleotide variants in enhancers or promoters may affect gene transcription by altering transcription factor binding sites. Here the authors present a meta-analysis empowered by a new statistical method covering thousands of ChIP-Seq experimen
Externí odkaz:
https://doaj.org/article/fb8abbc7f0654d9bb7b8ee5f2d4d9a03
Publikováno v:
F1000Research, Vol 11 (2022)
The position weight matrix, also called the position-specific scoring matrix, is the commonly accepted model to quantify the specificity of transcription factor binding to DNA. Position weight matrices are used in thousands of projects and software t
Externí odkaz:
https://doaj.org/article/5175c98fcccf42fb8b8924bb53449468
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108187- (2022)
N6-methyladenosine (m6A) is the most abundant, highly dynamic mRNA modification that regulates mRNA splicing, stability, and translation. The m6A epigenetic mark is erased by RNA demethylases ALKBH5 (AlkB Homolog 5) and FTO (Fat mass and obesity-asso
Externí odkaz:
https://doaj.org/article/13308de39cd4420fb3072857a5b28ff9
Publikováno v:
F1000Research, Vol 11 (2022)
The position weight matrix, also called the position-specific scoring matrix, is the commonly accepted model to quantify the specificity of transcription factor binding to DNA. Position weight matrices are used in thousands of projects and software t
Externí odkaz:
https://doaj.org/article/150a5338ebdc41ca993e6108f48d44e0
Autor:
Siddharth Sethi, Ilya E. Vorontsov, Ivan V. Kulakovskiy, Simon Greenaway, John Williams, Vsevolod J. Makeev, Steve D. M. Brown, Michelle M. Simon, Ann-Marie Mallon
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-22 (2020)
Abstract Background Efforts to elucidate the function of enhancers in vivo are underway but their vast numbers alongside differing enhancer architectures make it difficult to determine their impact on gene activity. By systematically annotating multi
Externí odkaz:
https://doaj.org/article/8f2ec8dcd8714977b405ae138aae5824