Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ivan Trus"'
Autor:
Kristien Van Reeth, Anna Parys, José Carlos Mancera Gracia, Ivan Trus, Koen Chiers, Philip Meade, Sean Liu, Peter Palese, Florian Krammer, Elien Vandoorn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Vaccines that protect against any H1N1 influenza A virus strain would be advantageous for use in pigs and humans. Here, we try to induce a pan-H1N1 antibody response in pigs by sequential vaccination with antigenically divergent H1N1 strains
Externí odkaz:
https://doaj.org/article/3f2b82ff53d24547bc30298e3d7a0e1f
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
The Zika virus 2015 epidemic showed an unusual phenotype for human flaviviruses, specifically fetal infection. We previously showed that in utero inoculation with the Asian Zika virus isolated from the human sample causes persistent infection in porc
Externí odkaz:
https://doaj.org/article/da1698fa6c1941da87cef6cd1e7d58e3
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTCongenital virus infections, for example cytomegalovirus and rubella virus infections, commonly affect the central nervous and hematological systems in fetuses and offspring. However, interactions between emerging congenital Zika virus and he
Externí odkaz:
https://doaj.org/article/392c8522db8145698bdfad2a38265abe
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Increasing the number of CpG dinucleotides in RNA viral genomes, while preserving the original amino acid composition, leads to impaired infection which does not cause disease. Beneficially, impaired infection evokes antiviral host immune responses p
Externí odkaz:
https://doaj.org/article/2bdfc318cd4841d6b725eced963cbaae
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1098-1107 (2019)
ABSTRACTStudies in mice showed that African Zika virus (ZIKV) strains cause more damage in embryos. These studies, however, were limited to the mouse-adapted African MR766 strain or infection at early gestation. Here, we compared infection of Asian a
Externí odkaz:
https://doaj.org/article/de203b968a724a908af183e2e3929fe0
Autor:
Ivan Trus, Joseph Darbellay, Yanyun Huang, Matthew Gilmour, David Safronetz, Volker Gerdts, Uladzimir Karniychuk
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1338-1343 (2018)
Externí odkaz:
https://doaj.org/article/720befe396f84cd18ca0b96dc2a0d1dc
Autor:
Ivan Trus, Daniel Udenze, Nathalie Berube, Colette Wheler, Marie-Jocelyne Martel, Volker Gerdts, Uladzimir Karniychuk
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Experimental increase of CpG dinucleotides in an RNA virus genome impairs infection providing a promising approach for vaccine development. While CpG recoding is an emerging and promising vaccine approach, little is known about infection phenotypes c
Externí odkaz:
https://doaj.org/article/316895b5c1504667972404afd82bee00
Autor:
Ivan Trus, Daniel Udenze, Brian Cox, Nathalie Berube, Rebecca E Nordquist, Franz Josef van der Staay, Yanyun Huang, Gary Kobinger, David Safronetz, Volker Gerdts, Uladzimir Karniychuk
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1008038 (2019)
Zika virus (ZIKV) infection during human pregnancy may lead to severe fetal pathology and debilitating impairments in offspring. However, the majority of infections are subclinical and not associated with evident birth defects. Potentially detrimenta
Externí odkaz:
https://doaj.org/article/2670f2c96c49436889c52c21e2d316a0
Autor:
Jiexiong Xie, Isaura Christiaens, Bo Yang, Ivan Trus, Bert Devriendt, Tingting Cui, Ruifang Wei, Hans J. Nauwynck
Publikováno v:
Veterinary Research, Vol 49, Iss 1, Pp 1-13 (2018)
Abstract Cellular entry mediators define whether the cell is permissive to PRRSV infection. Porcine sialoadhesin (pSn, Siglec-1) and CD163 are main entry mediators facilitating infection of porcine macrophages by PRRSV. Recently, Siglec-10 was demons
Externí odkaz:
https://doaj.org/article/1bfe48dba6bc4f45963d1eac5d9147b9
Publikováno v:
Viruses, Vol 13, Iss 9, p 1827 (2021)
The host’s immune status may affect virus evolution. Little is known about how developing fetal and placental immune milieus affect virus heterogeneity. This knowledge will help us better understand intra-host virus evolution and how new virus vari
Externí odkaz:
https://doaj.org/article/95bfaf5e22ab4e31ac15e2e0d72c3a09