Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Ivan Tarassov"'
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199258 (2018)
Mutations in mitochondrial DNA are an important source of severe and incurable human diseases. The vast majority of these mutations are heteroplasmic, meaning that mutant and wild-type genomes are present simultaneously in the same cell. Only a very
Externí odkaz:
https://doaj.org/article/c018c5d4637f488aa1ea3b1a1e1c327b
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 9354-9367 (2015)
In yeast Saccharomyces cerevisiae, ~3% of the lysine transfer RNA acceptor 1 (tRK1) pool is imported into mitochondria while the second isoacceptor, tRK2, fully remains in the cytosol. The mitochondrial function of tRK1 is suggested to boost mitochon
Externí odkaz:
https://doaj.org/article/34b445e28383443396c1bcd278d6da73
Publikováno v:
Cells, Vol 8, Iss 3, p 286 (2019)
Mitochondria harbor their own genetic system, yet critically depend on the import of a number of nuclear-encoded macromolecules to ensure their expression. In all eukaryotes, selected non-coding RNAs produced from the nuclear genome are partially red
Externí odkaz:
https://doaj.org/article/c707e982d4e44346914900321fa38b9a
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66228 (2013)
In human cell, a subset of small non-coding RNAs is imported into mitochondria from the cytosol. Analysis of the tRNA import pathway allowing targeting of the yeast tRNA(Lys)(CUU) into human mitochondria demonstrates a similarity between the RNA impo
Externí odkaz:
https://doaj.org/article/348b2bc3c8664ed19063e3e430d86332
Autor:
Sophie Kanga, Delphine Bernard, Anne-Marie Mager-Heckel, Zoi Erpapazoglou, Francesca Mattiroli, Titia K Sixma, Sébastien Léon, Danièle Urban-Grimal, Ivan Tarassov, Rosine Haguenauer-Tsapis
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38071 (2012)
The ubiquitin system is known to be involved in maintaining the integrity of mitochondria, but little is known about the role of deubiquitylating (DUB) enzymes in such functions. Budding yeast cells deleted for UBP13 and its close homolog UBP9 displa
Externí odkaz:
https://doaj.org/article/387af87ff8d3457880d96f9b75bb5b4d
Autor:
Regina Shebanova, Natalia Nikitchina, Nikita Shebanov, Vladimir Mekler, Konstantin Kuznedelov, Egor Ulashchik, Ruslan Vasilev, Olga Sharko, Vadim Shmanai, Ivan Tarassov, Konstantin Severinov, Nina Entelis, Ilya Mazunin
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, ⟨10.1093/nar/gkab1227⟩
Nucleic Acids Research, Oxford University Press, 2021, ⟨10.1093/nar/gkab1227⟩
CRISPR RNAs (crRNAs) that direct target DNA cleavage by Type V Cas12a nucleases consist of constant repeat-derived 5′-scaffold moiety and variable 3′-spacer moieties. Here, we demonstrate that removal of most of the 20-nucleotide scaffold has onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8552cd2be2eaf4c685f190b2cc7bcde
https://pubmed.ncbi.nlm.nih.gov/34951459
https://pubmed.ncbi.nlm.nih.gov/34951459
Autor:
Damien Jeandard, Anna Smirnova, Akinyemi Mandela Fasemore, Léna Coudray, Nina Entelis, Konrad U Förstner, Ivan Tarassov, Alexandre Smirnov
Publikováno v:
Nucleic Acids Research. 51:e16-e16
Proper RNA localisation is essential for physiological gene expression. Various kinds of genome-wide approaches permit to comprehensively profile subcellular transcriptomes. Among them, cell fractionation methods, that couple RNase treatment of isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958e309870e604d2108005d7dc818bb4
https://doi.org/10.1093/nar/gkac1183
https://doi.org/10.1093/nar/gkac1183
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c57072aec062eba58e12c5589b7468c4
https://pubmed.ncbi.nlm.nih.gov/34080151
https://pubmed.ncbi.nlm.nih.gov/34080151
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2277
Mitochondria have complex ultrastructure which includes continuous subcompartments, such as matrix, intermembrane space, and two membranes, as well as focal structures, such as nucleoids, RNA granules, and mitoribosomes. Comprehensive studies of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::700665bf54d597f5601c4e6220223d6a
https://pubmed.ncbi.nlm.nih.gov/34705262
https://pubmed.ncbi.nlm.nih.gov/34705262
Autor:
Ilya, Dovydenko, Mariya, Meschaninova, Anne-Marie, Heckel, Ivan, Tarassov, Alya, Venyaminova, Nina, Entelis
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2277
Defects in human mitochondrial genome can cause a wide range of clinical disorders that still do not have efficient therapies. The natural pathway of small noncoding RNA import can be exploited to address therapeutic RNAs into the mitochondria. To cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf2872f04dec723e5c9af0db001766a5
https://pubmed.ncbi.nlm.nih.gov/34080144
https://pubmed.ncbi.nlm.nih.gov/34080144