Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ivan T. Rebustini"'
Autor:
Sihan Li, Andrew Mecca, Jeewoo Kim, Giusy A. Caprara, Elizabeth L. Wagner, Ting-Ting Du, Leonid Petrov, Wenhao Xu, Runjia Cui, Ivan T. Rebustini, Bechara Kachar, Anthony W. Peng, Jung-Bum Shin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
How the ear achieves its remarkable sensitivity is still not fully understood. In this study, the authors demonstrate that the deafness protein myosin-VIIa and its isoforms are essential for tensioning the tip link, thereby sensitizing the auditory r
Externí odkaz:
https://doaj.org/article/1e1c4ebb707d4e36929a5c7886e6304d
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7745
The retinal pigment epithelium (RPE) expresses the Serpinf1 gene to produce pigment epithelium-derived factor (PEDF), a retinoprotective protein that is downregulated with cell senescence, aging and retinal degenerations. We determined the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e54b9eed1770b92d5e5c348082989f6
https://pubmed.ncbi.nlm.nih.gov/35887093
https://pubmed.ncbi.nlm.nih.gov/35887093
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b7f29adfd2125c6ceb3e0f76b12fa6
https://doi.org/10.1096/fasebj.2022.36.s1.r4747
https://doi.org/10.1096/fasebj.2022.36.s1.r4747
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a19b43683e996eeb915a631e1f035ece
https://doi.org/10.1096/fasebj.2022.36.s1.l7644
https://doi.org/10.1096/fasebj.2022.36.s1.l7644
Publikováno v:
Biochemical and biophysical research communications. 605
Pigment epithelium-derived factor (PEDF) is a secreted protein that is essential in tissue homeostasis and is involved in multiple functions in the eye, such as antiangiogenesis and neuroprotection. However, short retention in the retinal microenviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c21f63a551136575178b7bac90a4c13
https://pubmed.ncbi.nlm.nih.gov/35334413
https://pubmed.ncbi.nlm.nih.gov/35334413
Autor:
Longhua Hu, Bechara Kachar, Ivan T. Rebustini, Lenka Malec, Yeap Ng, Desu Chen, Peter W. Gunning, Roberto Weigert, Andrius Masedunskas, Seham Ebrahim, Max Weiss, Edna C. Hardeman, Jian Liu, Evan S. Krystofiak
Publikováno v:
Nat Cell Biol
Actomyosin networks, the cell’s major force production machineries, remodel cellular membranes during myriad dynamic processes(1,2) by assembling into various architectures with distinct force generation properties(3,4). While linear and branched a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a616f5c5a289b98a77d71b26f31b304
https://doi.org/10.1038/s41556-019-0365-7
https://doi.org/10.1038/s41556-019-0365-7
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5344, p 5344 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Retinoprotective proteins play important roles for retinal tissue integrity. They can directly affect the function and the survival of photoreceptors, and/or indirectly target the retinal pigment epithelium (RPE) and endothelial cells that support th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b83bda9800e5e27db499ab02613c2e
https://www.mdpi.com/1422-0067/22/10/5344
https://www.mdpi.com/1422-0067/22/10/5344
Autor:
Andrew A. Mecca, Jeewoo Kim, Giusy A. Caprara, Bechara Kachar, Ivan T. Rebustini, Sihan Li, Elizabeth L. Wagner, Anthony W. Peng, Runjia Cui, Wenhao Xu, Ting-Ting Du, Jung-Bum Shin, Leonid Petrov
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mutations in myosin-VIIa (MYO7A) cause Usher syndrome type 1, characterized by combined deafness and blindness. MYO7A is proposed to function as a motor that tensions the hair cell mechanotransduction (MET) complex, but conclusive evidence is lacking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9296fb013b77cbf7a208b50138fb9973
https://pubmed.ncbi.nlm.nih.gov/32350269
https://pubmed.ncbi.nlm.nih.gov/32350269
Autor:
Ivan T. Rebustini
Publikováno v:
Current Protocols in Cell Biology
The increasing repertoire of microRNAs expressed during organ development and their role in regulating organ morphogenesis provide a compelling need to develop methods to assess microRNA function using various in vitro and in vivo experimental models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3b15eccd83e5ae747a9596755bf0e5
https://doi.org/10.1002/cpcb.15
https://doi.org/10.1002/cpcb.15
Publikováno v:
Scientific Reports
The relative ease of identifying microRNAs and their increasing recognition as important regulators of organogenesis motivate the development of methods to efficiently assess microRNA function during organ morphogenesis. In this context, embryonic or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179b1f11fb9bb4ad47cd881c3da6d570