Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ivan T. Rebustini"'
Autor:
Sihan Li, Andrew Mecca, Jeewoo Kim, Giusy A. Caprara, Elizabeth L. Wagner, Ting-Ting Du, Leonid Petrov, Wenhao Xu, Runjia Cui, Ivan T. Rebustini, Bechara Kachar, Anthony W. Peng, Jung-Bum Shin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
How the ear achieves its remarkable sensitivity is still not fully understood. In this study, the authors demonstrate that the deafness protein myosin-VIIa and its isoforms are essential for tensioning the tip link, thereby sensitizing the auditory r
Externí odkaz:
https://doaj.org/article/1e1c4ebb707d4e36929a5c7886e6304d
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7745 (2022)
The retinal pigment epithelium (RPE) expresses the Serpinf1 gene to produce pigment epithelium-derived factor (PEDF), a retinoprotective protein that is downregulated with cell senescence, aging and retinal degenerations. We determined the expression
Externí odkaz:
https://doaj.org/article/c6cd5e8742bd47999bc1367020bf8b65
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5344 (2021)
Retinoprotective proteins play important roles for retinal tissue integrity. They can directly affect the function and the survival of photoreceptors, and/or indirectly target the retinal pigment epithelium (RPE) and endothelial cells that support th
Externí odkaz:
https://doaj.org/article/de8f0b4cc5be4287868cf385f4f9a48a
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Biochemical and biophysical research communications. 605
Pigment epithelium-derived factor (PEDF) is a secreted protein that is essential in tissue homeostasis and is involved in multiple functions in the eye, such as antiangiogenesis and neuroprotection. However, short retention in the retinal microenviro
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5344, p 5344 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Retinoprotective proteins play important roles for retinal tissue integrity. They can directly affect the function and the survival of photoreceptors, and/or indirectly target the retinal pigment epithelium (RPE) and endothelial cells that support th
Autor:
Longhua Hu, Bechara Kachar, Ivan T. Rebustini, Lenka Malec, Yeap Ng, Desu Chen, Peter W. Gunning, Roberto Weigert, Andrius Masedunskas, Seham Ebrahim, Max Weiss, Edna C. Hardeman, Jian Liu, Evan S. Krystofiak
Publikováno v:
Nat Cell Biol
Actomyosin networks, the cell’s major force production machineries, remodel cellular membranes during myriad dynamic processes(1,2) by assembling into various architectures with distinct force generation properties(3,4). While linear and branched a
Autor:
Andrew A. Mecca, Jeewoo Kim, Giusy A. Caprara, Bechara Kachar, Ivan T. Rebustini, Sihan Li, Elizabeth L. Wagner, Anthony W. Peng, Runjia Cui, Wenhao Xu, Ting-Ting Du, Jung-Bum Shin, Leonid Petrov
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mutations in myosin-VIIa (MYO7A) cause Usher syndrome type 1, characterized by combined deafness and blindness. MYO7A is proposed to function as a motor that tensions the hair cell mechanotransduction (MET) complex, but conclusive evidence is lacking
Autor:
Ivan T. Rebustini
Publikováno v:
Current Protocols in Cell Biology
The increasing repertoire of microRNAs expressed during organ development and their role in regulating organ morphogenesis provide a compelling need to develop methods to assess microRNA function using various in vitro and in vivo experimental models